puromycin (Q424696)

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chemical compound

3'-(L-alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine
(S)-3'-((2-Amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyladenosine
9-{3-deoxy-3-[(O-methyl-L-tyrosyl)amino]-beta-D-xylofuranosyl}-N,N-dimethyl-9H-purin-6-amine
Achromycin
Puromycin

Language	Label	Description	Also known as
English	puromycin	chemical compound	3'-(L-alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine (S)-3'-((2-Amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyladenosine 9-{3-deoxy-3-[(O-methyl-L-tyrosyl)amino]-beta-D-xylofuranosyl}-N,N-dimethyl-9H-purin-6-amine Achromycin Puromycin

Statements

type of chemical entity

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(2S)-2-amino-N-[(2S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanimidic acid

1 reference

based on heuristic

inferred from SMILES

biological research

1 reference

imported from Wikimedia project

English Wikipedia

chemical structure

Puromycin skeletal.svg
620 × 999; 20 KB

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471.223 dalton

1 reference

language of work or name

puromycin (English)

18 November 2016

stereoisomer of

2-amino-N-[5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide

1 reference

based on heuristic

inferred from InChI

chemical formula

C₂₂H₂₉N₇O₅

1 reference

language of work or name

puromycin (English)

18 November 2016

canonical SMILES

CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O

1 reference

language of work or name

puromycin (English)

18 November 2016

isomeric SMILES

CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O

1 reference

language of work or name

puromycin (English)

18 November 2016

World Health Organisation international non-proprietary name

puromycin (English)

1 reference

language of work or name

puromycin (English)

19 October 2016

Streptomyces lividans

1 reference

Expression of the Streptomyces alboniger pur cluster in Streptomyces lividans is dependent on the bldA-encoded tRNALeu

Acronychia pubescens

1 reference

Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens

Streptomyces alboniger

8 references

The pur8 gene from the pur cluster of Streptomyces alboniger encodes a highly hydrophobic polypeptide which confers resistance to puromycin

Biosynthesis of puromycin by Streptomyces alboniger: characterization of puromycin N-acetyltransferase.

Expression of the Streptomyces alboniger pur cluster in Streptomyces lividans is dependent on the bldA-encoded tRNALeu

Identification of the gene encoding an N-acetylpuromycin N-acetylhydrolase in the puromycin biosynthetic gene cluster from Streptomyces alboniger

The biosynthetic pathway of the aminonucleoside antibiotic puromycin, as deduced from the molecular analysis of the pur cluster of Streptomyces alboniger

Biosynthesis of Puromycin in Streptomyces alboniger : Regulation and Properties of O -Demethylpuromycin O -Methyltransferase

Isolation and properties of a puromycin acetyltransferase from puromycin-producing Streptomyces alboniger

The Pur10 protein encoded in the gene cluster for puromycin biosynthesis of Streptomyces alboniger is an NAD-dependent ATP dehydrogenase

1 reference

Herbicidins from Streptomyces sp. CB01388 Showing Anti- Cryptosporidium Activity.

subject has role

protein synthesis inhibitor

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

antineoplastic antimetabolite

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

trypanocidal agent

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

antimicrobial agent

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Commons category

Puromycin

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Identifiers

InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1

1 reference

language of work or name

puromycin (English)

18 November 2016

RXWNCPJZOCPEPQ-NVWDDTSBSA-N

2 references

language of work or name

puromycin (English)

18 November 2016

ChEBI release 2020-09-01

CAS Registry Number

2 references

Global Substance Registration System

language of work or name

puromycin (English)

18 November 2016

RXWNCPJZOCPEPQ-NVWDDTSBSA-N

CAS Common Chemistry

8 April 2021

https://commonchemistry.cas.org/detail?cas_rn=53-79-2

1 reference

language of work or name

PUROMYCIN (English)

18 November 2016

2 references

language of work or name

puromycin (English)

18 November 2016

matched by identifier from

RXWNCPJZOCPEPQ-NVWDDTSBSA-N

Reaxys registry number

70234

1 reference

language of work or name

puromycin (English)

19 October 2016

mapping relation type

2 references

language of work or name

PUROMYCIN (English)

18 November 2016

matched by identifier from

International Chemical Identifier

InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1

1 reference

language of work or name

PUROMYCIN (English)

18 November 2016

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

RXWNCPJZOCPEPQ-NVWDDTSBSA-N

UniChem compound ID

1 reference

MassBank accession ID

MSBNK-Keio_Univ-KO003828

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MSBNK-Keio_Univ-KO003829

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MSBNK-Keio_Univ-KO003830

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MSBNK-Keio_Univ-KO003831

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MSBNK-Keio_Univ-KO003832

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MSBNK-Keio_Univ-KO009213

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MSBNK-Keio_Univ-KO009214

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MSBNK-Keio_Univ-KO009215

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MSBNK-Keio_Univ-KO001686

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MSBNK-Keio_Univ-KO001687

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MSBNK-Keio_Univ-KO001688

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MSBNK-Keio_Univ-KO001689

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MSBNK-Keio_Univ-KO001690

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splash10-03k9-0900500000-0d48aed0c9497b5ab8f3

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splash10-03di-0900000000-af8be24075f803a58153

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splash10-03di-0900000000-571b6483dc540c02d098

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splash10-03di-0900000000-08775f201fb11e558b53

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splash10-00di-0000900000-6133e2c60106f3437756

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splash10-05fr-0005900000-a760a4943250cd5405b9

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splash10-0a4i-0809000000-eb619283ee6c689551e3

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splash10-0w29-0900000000-ca39c6d95b7bd8fba81b

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splash10-0udi-0900000000-253fadebaa39d03e1cd1

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splash10-0a4i-0219000000-6595a051c26ce2ee007b

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splash10-0udi-0920000000-cd34e8642bc7ea51cdb6

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splash10-00xr-0900000000-9100159b1a36c2984a3b

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DSSTox substance ID

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

matched by identifier from

RXWNCPJZOCPEPQ-NVWDDTSBSA-N

DSSTOX compound identifier

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MeSH descriptor ID

subject named as

Puromycin

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D02.241.223.200.380

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D03.633.100.759.590.138.711

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D09.408.051.788

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D13.570.583.138.711

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1 reference

matched by identifier from

RXWNCPJZOCPEPQ-NVWDDTSBSA-N

1 reference

language of work or name

puromycin (English)

19 October 2016

2 references

Global Substance Registration System

language of work or name

puromycin (English)

18 November 2016

matched by identifier from

RXWNCPJZOCPEPQ-NVWDDTSBSA-N

Probes And Drugs ID

0 references

1 reference

language of work or name

puromycin (English)

19 October 2016

IEDB Epitope ID

1 reference

Immune Epitope Database and Analysis Resource

IEDB Epitope ID

1 March 2022

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0 references

Encyclopædia Britannica Online ID

technology/puromycin

subject named as

puromycin

0 references

1 reference

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

Protein Data Bank

PDB structure ID

language of work or name

2DPT (English)

19 October 2016

1 reference

Protein Data Bank

PDB structure ID

language of work or name

4TVA (English)

19 October 2016

1 reference

Protein Data Bank

PDB structure ID

language of work or name

1Q7Y (English)

19 October 2016

1 reference

Protein Data Bank

PDB structure ID

language of work or name

3Q3D (English)

19 October 2016

Sitelinks

Wikipedia(19 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:Puromycin

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