Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice (Q48242315)

9 February 2018

title

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice (English)

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9 February 2018

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Chapman PF

1

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White GL

2

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Jones MW

3

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Cooper-Blacketer D

4

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Marshall VJ

5

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Irizarry M

6

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Younkin L

7

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Good MA

8

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Bliss TV

9

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Hyman BT

10

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Younkin SG

11

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Hsiao KK

12

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language of work or name

English

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publication date

1 March 1999

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9 February 2018

published in

Nature Neuroscience

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9 February 2018

volume

2

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issue

3

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page(s)

271-276

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9 February 2018

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

cites work

1 reference

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

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A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

21 January 2018

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Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

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Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

21 January 2018

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Amyloid, the presenilins and Alzheimer's disease

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

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A synaptic model of memory: long-term potentiation in the hippocampus

21 January 2018

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Long-term potentiation in awake mutant mice

21 January 2018

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Short-term synaptic plasticity

21 January 2018

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Perforant pathway changes and the memory impairment of Alzheimer's disease

21 January 2018

1 reference

Neuron atrophy during aging: programmed or sporadic?

21 January 2018

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Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches

21 January 2018

1 reference

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein

21 January 2018

1 reference

The synaptic vesicle cycle: a cascade of protein-protein interactions

21 January 2018

1 reference

A role for immediate-early transcription factors in learning and memory

21 January 2018

1 reference

Rab3A is essential for mossy fibre long-term potentiation in the hippocampus.

21 January 2018

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Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation

21 January 2018

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Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning

21 January 2018

1 reference

Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin

21 January 2018

1 reference

Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAM

21 January 2018

1 reference

A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43)

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/6374

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9 February 2018

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9 February 2018