Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import (Q49486091)

20 February 2018

title

Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import (English)

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20 February 2018

2

Blobel G

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20 February 2018

Floer M

1

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20 February 2018

Rexach M

series ordinal

3

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20 February 2018

language of work or name

English

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publication date

1 August 1997

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20 February 2018

Journal of Biological Chemistry

published in

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20 February 2018

volume

272

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20 February 2018

issue

31

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20 February 2018

page(s)

19538-19546

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20 February 2018

The nuclear transport factor karyopherin beta binds stoichiometrically to Ran-GTP and inhibits the Ran GTPase activating protein

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

21 January 2018

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Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes

21 January 2018

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A karyophilic protein forms a stable complex with cytoplasmic components prior to nuclear pore binding

21 January 2018

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Isolation of a protein that is essential for the first step of nuclear protein import

21 January 2018

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Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

21 January 2018

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Distinct functions for the two importin subunits in nuclear protein import

21 January 2018

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Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Sequence and characterization of cytoplasmic nuclear protein import factor p97

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes

21 January 2018

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Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import

21 January 2018

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Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins

21 January 2018

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Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

The essential yeast nucleoporin NUP159 is located on the cytoplasmic side of the nuclear pore complex and serves in karyopherin-mediated binding of transport substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

The 1.6 angstroms resolution crystal structure of nuclear transport factor 2 (NTF2)

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Role of the nuclear transport factor p10 in nuclear import

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Nucleotide-specific interaction of Ran/TC4 with nuclear transport factors NTF2 and p97.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Molecular interactions between the importin alpha/beta heterodimer and proteins involved in vertebrate nuclear protein import

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

A yeast mutant which accumulates precursor tRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

RanGAP1 induces GTPase activity of nuclear Ras-related Ran

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Molecular analysis of zyg-11, a maternal-effect gene required for early embryogenesis of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

nup1 mutants exhibit pleiotropic defects in nuclear pore complex function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Dynamic localization of the nuclear import receptor and its interactions with transport factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

A family of Ran binding proteins that includes nucleoporins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Nuclear protein import: Ran-GTP dissociates the karyopherin alphabeta heterodimer by displacing alpha from an overlapping binding site on beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Expression in yeast of binding regions of karyopherins alpha and beta inhibits nuclear import and cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

The GTPase superfamily: a conserved switch for diverse cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Nucleus-associated pools of Rna1p, the Saccharomyces cerevisiae Ran/TC4 GTPse activating protein involved in nucleus/cytosol transit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Different binding domains for Ran-GTP and Ran-GDP/RanBP1 on nuclear import factor p97

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Ran binding domains promote the interaction of Ran with p97/beta-karyopherin, linking the docking and translocation steps of nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

A giant nucleopore protein that binds Ran/TC4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Kinetic and Concentration Analysis Using BIA Technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

The GLFG repetitive region of the nucleoporin Nup116p interacts with Kap95p, an essential yeast nuclear import factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Purification of a Ran-interacting protein that is required for protein import into the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces Ran GTPase-activating protein (RanGAP) inhibition by karyopherin beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

A Ran-binding motif in nuclear pore proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.31.19538

A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

21 January 2018

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.272.31.19538

Nuclear PRP20 protein is required for mRNA export

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.272.31.19538

Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.272.31.19538

Identifiers

DOI

10.1074/JBC.272.31.19538

1 reference

20 February 2018

1 reference

20 February 2018