An asymmetrical Schiff base ligand with two position for coordination to metal was obtained by co... more An asymmetrical Schiff base ligand with two position for coordination to metal was obtained by condensation reaction between propane-1,2-diamine and (E)-3-(4-(dimethylamino)phenyl)acrylaldehyde. Characterization of the ligand and its Zn(II) complexes were performed suitably by means of the elemental analysis, FTIR, 1H, 13C NMR, UV-visible, melting points, and molar conductance. Lowering of the iminic bond energy, red shifts of electronic transition bands, and down fielded azomethine proton signals well confirm coordination of ligand to zinc center. All compounds were stable at room temperature for the many long times. All complexes were suggested to be nonelectrolytes due to low molar conductivities. After characterization, antibacterial properties of all compounds have been studied against two Gram-negative bacteria, Escherichia coli (ATCC 25922) and Pseudomonas aeroginosa (ATCC 9027), and two Gram-positive bacteria, Staphylococcus aureus (ATCC 6538) and Bacillus subtilis. The ligand and Zn(II) coordination compounds demonstrated acceptable antibacterial activities. Zinc complexes showed higher activity than the parental ligand. The compounds inhibited the growth of Gram-negative more efficiently than Gram-positive bacterial strains. MIC and MBC of all compounds as alternative data for antibacterial activity were reported in μg/mL.
Five mercury (II) complexes of a recently synthesized bidentate Schiff base ligand were prepared.... more Five mercury (II) complexes of a recently synthesized bidentate Schiff base ligand were prepared. All mercury (II) coordinated compounds were characterized perfectly with the aid of elemental analysis, FTIR,1H NMR, 13C NMR, UV-Visible and molar conductance. Morphology of mercury bromide particles as typical one in the view point of shape and size were qualified by SEM. Electrochemical behaviors of Hg (II) complexes as compared with ligand were evaluated by using cyclic voltammetry method. The results showed a similar redox behavior for coordinated ligand in complexes with respect to free ligand. Antibacterial/antifungal properties of the compounds were checked against three Gram-negative bacterium Escherichia coli (ATCC 25922), Pseudomunase aeroginosa (ATCC 9027), Salmonella Spp., and two Gram-positive bacterium Staphylococcus aureus (ATCC 6538), Corynebacterium renale and three fungal strains (Aspergillus niger, Penicillium chrysogenum and Candida albicans). The results revealed acceptable antibacterial/antifungal activities for most of the compounds. HgL(N3)2 has shown remarkable activity against Penicillium chrysogenum. Furthermore theoretical investigation of ligand and mercury complexes was performed by Gaussian 98 at the UB3LYP/LANL2MB level of theory. Some structural and energetic data such as bond length, bond angle, torsional angle, dipole moment of compounds, Gibbs free energy, enthalpy and entropy of complex formation were evaluated.
A new symmetrical bidentate Schiff base ligand (L) was applied for
the synthesis of some new cad... more A new symmetrical bidentate Schiff base ligand (L) was applied for
the synthesis of some new cadmium coordination compounds with general formula of [Cd(L)X2] in which X is halide and pseudo-halide. The ligand and all cadmium complexes were characterized by some techniques such as elemental analysis, FT-IR, 1H, 13C NMR, UV-Visible and molar conductance.
Electrochemical behavior of ligand and Cd(II) complexes were investigated by cyclic voltammetry method. Morphology and shape of [Cd(L)Cl2] particles were depicted by SEM. Antimicrobial properties such as antibacterial and antifungal activities of the complexes as compared with ligand were checked against three Gram-negative bacteria; Escherichia coli (ATCC 25922), Pseudomunase aeroginosa (ATCC 9027) and Salmonella Spp. and two Grampositive bacteria; Staphylococcus aureus (ATCC 6538) and Corynebacterium renale and three fungal strains including Aspergillus Niger, Penicillium chrysogenum and Candida albicans. The results revealed appropriate antibacterial and antifungal activities for all compounds, and it was also found that the coordination of ligand to Cd (II) lead to an increase in the antimicrobial activities in most of cases.
A novel symmetrical Schiff base ligand was prepared by condensation reaction of 2,2-dimethyl-1.3-... more A novel symmetrical Schiff base ligand was prepared by condensation reaction of 2,2-dimethyl-1.3-diaminopropane and (E)3-(2nitrophenyl)acrylaldehyde. The ligand and its Zn(II) coordination compounds were well characterized by the elemental analysis, FTIR, 1H, 13C NMR, UV–vis spectra and molar conductance. Thermal behaviors of all compounds were investigated from the room temperature to 600 °C with a heating rate of 10 °C/min. Furthermore some decomposition thermo-kinetic parameters were evaluated by Coats–Redfern equation at each decomposition step. Electrochemical properties of ligand and its complexes were studied by cyclic voltammetry technique. Also antibacterial/antifungal activities of the ligand and its complexes were tested against three Gram-negative bacteria Escherichia coli (ATCC 25922), Salmonella spp. and Pseudomonas aeruginosa (ATCC 9027) and two Gram-positive bacteria Staphylococcus aureus (ATCC 6538) and Corynebacterium renale and also three fungi (Aspergillus niger, Penicillium chrysogenum and Candida albicans). The results exhibited suitable antibacterial/antifungal properties for ligand and Zn(II) complexes. The study has shown that the complexation of ligand to zinc center lead to enhancement of antibacterial/antifungal activity.
An asymmetrical Schiff base ligand with two position for coordination to metal was obtained by co... more An asymmetrical Schiff base ligand with two position for coordination to metal was obtained by condensation reaction between propane-1,2-diamine and (E)-3-(4-(dimethylamino)phenyl)acrylaldehyde. Characterization of the ligand and its Zn(II) complexes were performed suitably by means of the elemental analysis, FTIR, 1H, 13C NMR, UV-visible, melting points, and molar conductance. Lowering of the iminic bond energy, red shifts of electronic transition bands, and down fielded azomethine proton signals well confirm coordination of ligand to zinc center. All compounds were stable at room temperature for the many long times. All complexes were suggested to be nonelectrolytes due to low molar conductivities. After characterization, antibacterial properties of all compounds have been studied against two Gram-negative bacteria, Escherichia coli (ATCC 25922) and Pseudomonas aeroginosa (ATCC 9027), and two Gram-positive bacteria, Staphylococcus aureus (ATCC 6538) and Bacillus subtilis. The ligand and Zn(II) coordination compounds demonstrated acceptable antibacterial activities. Zinc complexes showed higher activity than the parental ligand. The compounds inhibited the growth of Gram-negative more efficiently than Gram-positive bacterial strains. MIC and MBC of all compounds as alternative data for antibacterial activity were reported in μg/mL.
Five mercury (II) complexes of a recently synthesized bidentate Schiff base ligand were prepared.... more Five mercury (II) complexes of a recently synthesized bidentate Schiff base ligand were prepared. All mercury (II) coordinated compounds were characterized perfectly with the aid of elemental analysis, FTIR,1H NMR, 13C NMR, UV-Visible and molar conductance. Morphology of mercury bromide particles as typical one in the view point of shape and size were qualified by SEM. Electrochemical behaviors of Hg (II) complexes as compared with ligand were evaluated by using cyclic voltammetry method. The results showed a similar redox behavior for coordinated ligand in complexes with respect to free ligand. Antibacterial/antifungal properties of the compounds were checked against three Gram-negative bacterium Escherichia coli (ATCC 25922), Pseudomunase aeroginosa (ATCC 9027), Salmonella Spp., and two Gram-positive bacterium Staphylococcus aureus (ATCC 6538), Corynebacterium renale and three fungal strains (Aspergillus niger, Penicillium chrysogenum and Candida albicans). The results revealed acceptable antibacterial/antifungal activities for most of the compounds. HgL(N3)2 has shown remarkable activity against Penicillium chrysogenum. Furthermore theoretical investigation of ligand and mercury complexes was performed by Gaussian 98 at the UB3LYP/LANL2MB level of theory. Some structural and energetic data such as bond length, bond angle, torsional angle, dipole moment of compounds, Gibbs free energy, enthalpy and entropy of complex formation were evaluated.
A new symmetrical bidentate Schiff base ligand (L) was applied for
the synthesis of some new cad... more A new symmetrical bidentate Schiff base ligand (L) was applied for
the synthesis of some new cadmium coordination compounds with general formula of [Cd(L)X2] in which X is halide and pseudo-halide. The ligand and all cadmium complexes were characterized by some techniques such as elemental analysis, FT-IR, 1H, 13C NMR, UV-Visible and molar conductance.
Electrochemical behavior of ligand and Cd(II) complexes were investigated by cyclic voltammetry method. Morphology and shape of [Cd(L)Cl2] particles were depicted by SEM. Antimicrobial properties such as antibacterial and antifungal activities of the complexes as compared with ligand were checked against three Gram-negative bacteria; Escherichia coli (ATCC 25922), Pseudomunase aeroginosa (ATCC 9027) and Salmonella Spp. and two Grampositive bacteria; Staphylococcus aureus (ATCC 6538) and Corynebacterium renale and three fungal strains including Aspergillus Niger, Penicillium chrysogenum and Candida albicans. The results revealed appropriate antibacterial and antifungal activities for all compounds, and it was also found that the coordination of ligand to Cd (II) lead to an increase in the antimicrobial activities in most of cases.
A novel symmetrical Schiff base ligand was prepared by condensation reaction of 2,2-dimethyl-1.3-... more A novel symmetrical Schiff base ligand was prepared by condensation reaction of 2,2-dimethyl-1.3-diaminopropane and (E)3-(2nitrophenyl)acrylaldehyde. The ligand and its Zn(II) coordination compounds were well characterized by the elemental analysis, FTIR, 1H, 13C NMR, UV–vis spectra and molar conductance. Thermal behaviors of all compounds were investigated from the room temperature to 600 °C with a heating rate of 10 °C/min. Furthermore some decomposition thermo-kinetic parameters were evaluated by Coats–Redfern equation at each decomposition step. Electrochemical properties of ligand and its complexes were studied by cyclic voltammetry technique. Also antibacterial/antifungal activities of the ligand and its complexes were tested against three Gram-negative bacteria Escherichia coli (ATCC 25922), Salmonella spp. and Pseudomonas aeruginosa (ATCC 9027) and two Gram-positive bacteria Staphylococcus aureus (ATCC 6538) and Corynebacterium renale and also three fungi (Aspergillus niger, Penicillium chrysogenum and Candida albicans). The results exhibited suitable antibacterial/antifungal properties for ligand and Zn(II) complexes. The study has shown that the complexation of ligand to zinc center lead to enhancement of antibacterial/antifungal activity.
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Papers by sahar yadegari
the synthesis of some new cadmium coordination compounds with general formula of [Cd(L)X2] in which X is halide and pseudo-halide. The ligand and all cadmium complexes were characterized by some techniques such as elemental analysis, FT-IR, 1H, 13C NMR, UV-Visible and molar conductance.
Electrochemical behavior of ligand and Cd(II) complexes were investigated by cyclic voltammetry method. Morphology and shape of [Cd(L)Cl2] particles were depicted by SEM. Antimicrobial properties such as antibacterial and antifungal activities of the complexes as compared with ligand were checked against three Gram-negative bacteria; Escherichia coli (ATCC 25922), Pseudomunase aeroginosa (ATCC 9027) and Salmonella Spp. and two Grampositive bacteria; Staphylococcus aureus (ATCC 6538) and Corynebacterium renale and three fungal strains including Aspergillus Niger, Penicillium chrysogenum and Candida albicans. The results revealed appropriate antibacterial and antifungal activities for all compounds, and it was also found that the coordination of ligand to Cd (II) lead to an increase in the antimicrobial activities in most of cases.
the synthesis of some new cadmium coordination compounds with general formula of [Cd(L)X2] in which X is halide and pseudo-halide. The ligand and all cadmium complexes were characterized by some techniques such as elemental analysis, FT-IR, 1H, 13C NMR, UV-Visible and molar conductance.
Electrochemical behavior of ligand and Cd(II) complexes were investigated by cyclic voltammetry method. Morphology and shape of [Cd(L)Cl2] particles were depicted by SEM. Antimicrobial properties such as antibacterial and antifungal activities of the complexes as compared with ligand were checked against three Gram-negative bacteria; Escherichia coli (ATCC 25922), Pseudomunase aeroginosa (ATCC 9027) and Salmonella Spp. and two Grampositive bacteria; Staphylococcus aureus (ATCC 6538) and Corynebacterium renale and three fungal strains including Aspergillus Niger, Penicillium chrysogenum and Candida albicans. The results revealed appropriate antibacterial and antifungal activities for all compounds, and it was also found that the coordination of ligand to Cd (II) lead to an increase in the antimicrobial activities in most of cases.