CACNG1

CACNG1
识别号
别名	CACNG1；, CACNLG, calcium voltage-gated channel auxiliary subunit gamma 1
外部ID	OMIM：114209 MGI：1206582 HomoloGene：582 GeneCards：CACNG1
为以下药物的标靶
	bepridil hydrochloride monohydrate
基因位置（人类）
染色体	17号染色体
终止	67,056,797 bp
基因位置（小鼠）
染色体	小鼠11号染色体
终止	107,607,348 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• voltage-gated calcium channel activity; • 血浆蛋白结合; • voltage-gated ion channel activity; • calcium channel activity; • calcium channel regulator activity;
细胞组分	• 电压依赖性钙通道; • integral component of membrane; • 细胞膜; • 膜; • integral component of plasma membrane; • 横小管; • 肌膜; • L-type voltage-gated calcium channel complex;
生物学过程	• regulation of ion transmembrane transport; • 肌肉收缩; • ion transport; • calcium ion transmembrane transport; • sarcoplasmic reticulum calcium ion transport; • calcium ion transport; • regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; • cardiac conduction;
	Sources:Amigo / QuickGO
直系同源
	786
	12299
	ENSG00000108878
	ENSMUSG00000020722
	Q06432
	O70578
	NM_000727
	NM_007582
	NP_000718
	NP_031608
	维基数据
查看/编辑人类	查看/编辑小鼠

电压依赖性钙通道γ1亚基是一种由CACNG1基因编码的蛋白质。^[6]^[7]

L型钙通道由五个亚基组成。由该基因编码的蛋白质代表γ亚基之一，是几种γ亚基蛋白质之一。这种特殊的γ亚基是骨骼肌1,4-二氢吡啶敏感性钙通道的一部分，是一种在激发 - 收缩偶联中起作用的完整膜蛋白。该基因是PMP-22 / EMP / MP20家族的神经元钙通道γ亚基基因亚家族的成员，并且位于具有两个相似的γ亚基编码基因的簇中。^[7]

参考文献

^ 對Calcium voltage-gated channel auxiliary subunit gamma 1起作用的藥物；在維基數據上查看/編輯參考.
^ ^2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000108878 - Ensembl, May 2017
^ ^3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000020722 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Iles, D. E.; Segers, B.; Sengers, R. C.; Monsieurs, K.; Heytens, L.; Halsall, P. J.; Hopkins, P. M.; Ellis, F. R.; Hall-Curran, J. L. Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility. Human Molecular Genetics. 1993-7, 2 (7): 863–868 [2018-08-15]. ISSN 0964-6906. PMID 8395940. （原始内容存档于2018-08-15）. 请检查|date=中的日期值 (帮助)
^ ^7.0 ^7.1 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 [Homo sapiens (human)] - Gene - NCBI. www.ncbi.nlm.nih.gov. [2018-08-15]. （原始内容存档于2019-02-15）.

这是一篇与生物学相关的小作品。您可以通过编辑或修订扩充其内容。

[1] 對Calcium voltage-gated channel auxiliary subunit gamma 1起作用的藥物；在維基數據上查看/編輯參考.

[refGRCh38Ensembl-2] 2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000108878 - Ensembl, May 2017

[refGRCm38Ensembl-3] 3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000020722 - Ensembl, May 2017

[4] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[6] Iles, D. E.; Segers, B.; Sengers, R. C.; Monsieurs, K.; Heytens, L.; Halsall, P. J.; Hopkins, P. M.; Ellis, F. R.; Hall-Curran, J. L. Genetic mapping of the beta 1- and gamma-subunits of the human skeletal muscle L-type voltage-dependent calcium channel on chromosome 17q and exclusion as candidate genes for malignant hyperthermia susceptibility. Human Molecular Genetics. 1993-7, 2 (7): 863–868 [2018-08-15]. ISSN 0964-6906. PMID 8395940. （原始内容存档于2018-08-15）. 请检查|date=中的日期值 (帮助)

[:0-7] 7.0 ^7.1 CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 [Homo sapiens (human)] - Gene - NCBI. www.ncbi.nlm.nih.gov. [2018-08-15]. （原始内容存档于2019-02-15）.

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