Protopone is an extinct genus of ants in the formicid subfamily Ponerinae described from fossils found in Europe and Asia. There are seven described species placed into the genus, Protopone? dubia, Protopone germanica, Protopone magna, Protopone oculata, Protopone primigena, Protopone sepulta, and Protopone vetula. Protopone is one several Lutetian Ponerinae genera.