Research Interests:
Research Interests:
Research Interests:
We investigate changes in macular choroidal thickness in eyes without diabetic retinopathy of patients with various durations of diabetes, using enhanced depth imaging optical coherence tomography (EDI OCT). The 134 Type-2 diabetic... more
We investigate changes in macular choroidal thickness in eyes without diabetic retinopathy of patients with various durations of diabetes, using enhanced depth imaging optical coherence tomography (EDI OCT). The 134 Type-2 diabetic patients who presented without diabetic retinopathy were prospectively imaged using EDI OCT on Heidelberg Spectralis (Heidelberg Engineering, Heidelberg, Germany) sd-OCT. The patients with diabetes were classified into three groups, according to the duration of diabetes: Group I (5-9 years, n = 63); Group II (10-14 years, n = 37); Group III (15-40 years, n = 34). The retinal and choroidal thickness was evaluated between these groups at central fovea and at the regions at 500-mm intervals up to 1500 mm temporal and nasal to the fovea. The central foveal retinal thickness was significantly different between groups (group I: 273.05 ± 19.51 µ, group II: 267.12 ± 20.78 µ, group III: 261.34 ± 22.27 µ; p = 0.04). The choroidal thickness measurements at central fovea, at 500, 1000, and 1500 micron intervals temporal and nasal to the center of the fovea were not significantly different between groups. The duration of diabetes was weakly correlated with choroidal thickness in all measured distances and they were not statistically significant. The central foveal choroidal thickness was weakly correlated with serum creatinine (r = -0.18, p = 0.03). Foveal retinal thickness was significantly decreased in patients with longer duration of diabetes. Duration of diabetes does not seem to be related to foveal chorodial thickness. On the other hand, the weak relation between creatinine and choroidal thickness may be evaluated further. The choroidal thickness changes that may be an early sign of nephropathy can be submitted to an easy, noninvasive scanning test at the same time.
Research Interests:
Research Interests:
Research Interests:
Research Interests:
Laser in situ keratomileusis (LASIK) retreatments are now commonly performed surgeries as LASIK is increasingly used to correct refractive errors. The most important criterion to select the retreatment technique is residual stromal bed... more
Laser in situ keratomileusis (LASIK) retreatments are now commonly performed surgeries as LASIK is increasingly used to correct refractive errors. The most important criterion to select the retreatment technique is residual stromal bed thickness. If there is enough stromal bed, ...
Research Interests:
To evaluate the effect of long-term application of bimatoprost and latanoprost on the anterior chamber depth of primary open-angle glaucoma patients. The anterior chamber depth (ACD) and axial length (AL) of patients using prostaglandin... more
To evaluate the effect of long-term application of bimatoprost and latanoprost on the anterior chamber depth of primary open-angle glaucoma patients. The anterior chamber depth (ACD) and axial length (AL) of patients using prostaglandin analogues for open-angle glaucoma (group I) and an age- and gender-adjusted control group (group II) were measured by ultrasonography. Patients using bimatoprost and those using latanoprost were also compared in terms of ACD and AL. The mean ACD of group I (27 eyes of 27 subjects) was significantly lower than that of group II (30 eyes of 30 subjects) (p = .012). Similarly, the ratio of ACD to AL was significantly lower in group I compared with group II (p = .001). The ACDs of patients using bimatoprost or latanoprost and the control group were not significantly different by Kruskal-Wallis test (p = .056), but the differences of these 3 groups in ACD/AL ratios were significant (p = .004). When the Mann Whitney U test was used for pairwise comparison, there was a significant difference between the control group and the patients using latanoprost or bimatoprost in terms of the ACD/AL ratio (p = .008 for each). There was no difference between the patients using latanoprost and those using bimatoprost in terms of the ACD/AL ratio (p = .4). The ACD of patients on prolonged therapy with prostaglandin analogues seems to be lower than than that of the control group. However, prospective long-term studies on large number of subjects are needed to evaluate the effect of each type of prostaglandin on ocular structures.
Research Interests:
We aimed to evaluate the dynamic function of iris muscle in asymmetric pseudoexfoliation patients by videonystagmography. 15 patients with asymmetric pseudoexfoliation and 15 control subjects were included. The function of iris muscle was... more
We aimed to evaluate the dynamic function of iris muscle in asymmetric pseudoexfoliation patients by videonystagmography. 15 patients with asymmetric pseudoexfoliation and 15 control subjects were included. The function of iris muscle was assessed by the pupillometry test of the videonystagmography by calculating the percent of change in pupillary diameter in unit time during fixation to an accommodative target, light reaction, convergence, and divergence. There were significant differences between groups in the reaction during fixation (p: 0.01), in light reaction (p: 0.014), and in divergence-induced mydriasis (p: 0.003). In all of these, the difference between control eyes and pseudoexfoliative eyes of patients with PXS was significant. Pupillometry seems to be a promising noninvasive method to detect the clinical signs of PXS and may be useful for an accurate diagnosis.
Research Interests: Multidisciplinary, Humans, Smooth muscle, Female, Male, and 6 moreLight, Aged, Middle Aged, Iris, Pupil, and Video Recording
Although neurotrophic ulcers due to herpes zoster are seldom, there may be challenging cases. Especially neurotrophic corneal ulcers after cataract operations should arise the possibility of a previous herpes zoster attack and the... more
Although neurotrophic ulcers due to herpes zoster are seldom, there may be challenging cases. Especially neurotrophic corneal ulcers after cataract operations should arise the possibility of a previous herpes zoster attack and the treatment plan should be prepared accordingly. This case highlights the importance of thorough evaluation of cataract patients in order not to miss a previous diagnosis of herpes.
Research Interests:
Investigating the relationship between the serum levels of zinc and copper with blepharitis. Twenty seven patients with blepharitis and 24 control group patients were evaluated for Schirmer, fluorescein break up time (FBUT) scores and... more
Investigating the relationship between the serum levels of zinc and copper with blepharitis. Twenty seven patients with blepharitis and 24 control group patients were evaluated for Schirmer, fluorescein break up time (FBUT) scores and serum levels of zinc and copper. Symptoms and clinical examination scores of blepharitis patients were also assessed. The serum level of zinc (65.78+/-15.51 in patients with blepharitis and 65.71+/-10.43 in patients without blepharitis, normal values in the laboratory: 70-127 microg/dl) and copper (67.17+/-22.24 in patients with blepharitis and 69.35+/-14.44 in patients without blepharitis, normal values in the laboratory: 70-150 microg/dl) were not different between the two groups. The symptom and clinical examination scores of blephraritis patients were not correlated with the serum levels of either zinc or copper. The zinc and copper levels in serum do not seem to be related to blepharitis. Their tear levels and sensory status of cornea should also be evaluated to better evaluate a possible relation.