Background: This article investigates the genomic knowledge of oncology care physicians in the ad... more Background: This article investigates the genomic knowledge of oncology care physicians in the adoption of clinical genomics. We apply Rogers' knowledge framework from his diffusion of innovation theory to identify three types of knowledge in the process of translation and adoption: awareness, how-to, and principles knowledge. The objectives of this systematic review are to: (1) examine the level of knowledge among physicians in clinical cancer genomics, and (2) identify potential interventions or strategies for development of genomic education for oncology practice. Methods: We follow the PRIMSA statement protocol and conduct a search of five relevant electronic databases. Our review focuses on: (1) genomic knowledge of oncogenomics or genomic services in oncology practices among physicians, and (2) interventions or strategies to provide genomic education of oncogenomics for physicians. Results: We include twenty-one studies in our analysis. Nine focus on interventions to provide genomic education for cancer care. Overall, physicians' knowledge of oncogenomics among the three types is limited. The genomic literacy of physicians vary by their provider specialty, location, years of practice, and the type of genomic services. The three distinctions of knowledge offer a sophisticated and helpful tool to design effective strategies and interventions to provide genomic education for cancer treatment. In the nine educational intervention studies, the main intervention outcomes are changes in awareness, referral rates, genomic confidence, and genomic knowledge. Conclusion: Rogers' diffusion of innovation model allows us to differentiate three types of knowledge in the development and adoption of clinical genomics. This analytical lens can inform potential avenues to design more effective strategies and interventions to provide genomic education for oncology practice. We identified and synthesized a dearth of high quality studies that can inform the most effective educational outcomes of these interventions. Future research should attend to improving applications of genomic services in clinical practices, along with organizational change engendered by genomics in oncology practice.
Background: It has been over a decade since the completion of the Human Genome Project (HGP), gen... more Background: It has been over a decade since the completion of the Human Genome Project (HGP), genomic sequencing technologies have yet to become parts of standard of care in Canada. This study investigates medical oncologists' (MOs) genomic literacy and their experiences based on their participation in a cancer genomics trial in British Columbia, Canada.
Methods: The authors conducted a survey of MOs from British Columbia, Canada (n = 31, 52.5% response rate),who are actively involved in a clinical genomics trial called Personalized Onco-Genomics (POG). The authors also measured MOs’ level of genomic knowledge and attitudes about clinical genomics in cancer medicine.
Results: The findings show a low to moderate level of genomic literacy among MOs. MOs located outside theVancouver area (the major urban center) reported less knowledge about new genetics technologies compared to those located in the major metropolitan area (26.7 vs 73.3%, P < 0.07, Fisher exact test). Forty-two percent of all MOs thought medical training programs do not offer enough genomic training. The majority of the respondents thought genomics will have major impact on drug discovery (67.7%), and treatment selection (58%) in the next5 years. They also thought the major challenges are cost (61.3%), patient genomic literacy (48.3%), and clinical utility of genomics (42%).
Conclusions: The data suggest a high need to increase genomic literacy among MOs and other doctors in medical school training programs and beyond, especially to physicians in regional areas who may need more educational interventions. Initiatives like POG play a critical role in the education of MOs and the integration of big data clinical genomics into cancer care.
Big data has captured the interests of scholars across many disciplines over the last half a deca... more Big data has captured the interests of scholars across many disciplines over the last half a decade. Business scholars have increasingly turned their attention to the impact of this emerging phenomenon. Despite the rise in attention, our understanding of what big data is and what it means for organizations and institutional actors remains uncertain. In this study, we conduct a systematic review on " big data " across business scholarship over the past six years (2009–2014). We analyzed 219 peer-reviewed academic papers from 152 journals from the most comprehensive business literature database. We conducted the systematic review both quantitatively and qualitatively using the data analysis software NVivo10. Our results reveal several key insights about the scholarly investigation of big data, including its top benefits and challenges. Overall, we found that big data remains a fragmented, early-stage domain of research in terms of theoretical grounding, methodological diversity and empirically oriented work. These challenges serve to improve our understanding of the state of big data in contemporary research, and to further prompt scholars and decision-makers to advance future research in the most productive manner.
Background: This article investigates the genomic knowledge of oncology care physicians in the ad... more Background: This article investigates the genomic knowledge of oncology care physicians in the adoption of clinical genomics. We apply Rogers' knowledge framework from his diffusion of innovation theory to identify three types of knowledge in the process of translation and adoption: awareness, how-to, and principles knowledge. The objectives of this systematic review are to: (1) examine the level of knowledge among physicians in clinical cancer genomics, and (2) identify potential interventions or strategies for development of genomic education for oncology practice. Methods: We follow the PRIMSA statement protocol and conduct a search of five relevant electronic databases. Our review focuses on: (1) genomic knowledge of oncogenomics or genomic services in oncology practices among physicians, and (2) interventions or strategies to provide genomic education of oncogenomics for physicians. Results: We include twenty-one studies in our analysis. Nine focus on interventions to provide genomic education for cancer care. Overall, physicians' knowledge of oncogenomics among the three types is limited. The genomic literacy of physicians vary by their provider specialty, location, years of practice, and the type of genomic services. The three distinctions of knowledge offer a sophisticated and helpful tool to design effective strategies and interventions to provide genomic education for cancer treatment. In the nine educational intervention studies, the main intervention outcomes are changes in awareness, referral rates, genomic confidence, and genomic knowledge. Conclusion: Rogers' diffusion of innovation model allows us to differentiate three types of knowledge in the development and adoption of clinical genomics. This analytical lens can inform potential avenues to design more effective strategies and interventions to provide genomic education for oncology practice. We identified and synthesized a dearth of high quality studies that can inform the most effective educational outcomes of these interventions. Future research should attend to improving applications of genomic services in clinical practices, along with organizational change engendered by genomics in oncology practice.
Background: It has been over a decade since the completion of the Human Genome Project (HGP), gen... more Background: It has been over a decade since the completion of the Human Genome Project (HGP), genomic sequencing technologies have yet to become parts of standard of care in Canada. This study investigates medical oncologists' (MOs) genomic literacy and their experiences based on their participation in a cancer genomics trial in British Columbia, Canada.
Methods: The authors conducted a survey of MOs from British Columbia, Canada (n = 31, 52.5% response rate),who are actively involved in a clinical genomics trial called Personalized Onco-Genomics (POG). The authors also measured MOs’ level of genomic knowledge and attitudes about clinical genomics in cancer medicine.
Results: The findings show a low to moderate level of genomic literacy among MOs. MOs located outside theVancouver area (the major urban center) reported less knowledge about new genetics technologies compared to those located in the major metropolitan area (26.7 vs 73.3%, P < 0.07, Fisher exact test). Forty-two percent of all MOs thought medical training programs do not offer enough genomic training. The majority of the respondents thought genomics will have major impact on drug discovery (67.7%), and treatment selection (58%) in the next5 years. They also thought the major challenges are cost (61.3%), patient genomic literacy (48.3%), and clinical utility of genomics (42%).
Conclusions: The data suggest a high need to increase genomic literacy among MOs and other doctors in medical school training programs and beyond, especially to physicians in regional areas who may need more educational interventions. Initiatives like POG play a critical role in the education of MOs and the integration of big data clinical genomics into cancer care.
Big data has captured the interests of scholars across many disciplines over the last half a deca... more Big data has captured the interests of scholars across many disciplines over the last half a decade. Business scholars have increasingly turned their attention to the impact of this emerging phenomenon. Despite the rise in attention, our understanding of what big data is and what it means for organizations and institutional actors remains uncertain. In this study, we conduct a systematic review on " big data " across business scholarship over the past six years (2009–2014). We analyzed 219 peer-reviewed academic papers from 152 journals from the most comprehensive business literature database. We conducted the systematic review both quantitatively and qualitatively using the data analysis software NVivo10. Our results reveal several key insights about the scholarly investigation of big data, including its top benefits and challenges. Overall, we found that big data remains a fragmented, early-stage domain of research in terms of theoretical grounding, methodological diversity and empirically oriented work. These challenges serve to improve our understanding of the state of big data in contemporary research, and to further prompt scholars and decision-makers to advance future research in the most productive manner.
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Methods: The authors conducted a survey of MOs from British Columbia, Canada (n = 31, 52.5% response rate),who are actively involved in a clinical genomics trial called Personalized Onco-Genomics (POG). The authors also measured MOs’ level of genomic knowledge and attitudes about clinical genomics in cancer medicine.
Results: The findings show a low to moderate level of genomic literacy among MOs. MOs located outside theVancouver area (the major urban center) reported less knowledge about new genetics technologies compared to those located in the major metropolitan area (26.7 vs 73.3%, P < 0.07, Fisher exact test). Forty-two percent of all MOs thought medical training programs do not offer enough genomic training. The majority of the respondents thought genomics will have major impact on drug discovery (67.7%), and treatment selection (58%) in the next5 years. They also thought the major challenges are cost (61.3%), patient genomic literacy (48.3%), and clinical utility of genomics (42%).
Conclusions: The data suggest a high need to increase genomic literacy among MOs and other doctors in medical school training programs and beyond, especially to physicians in regional areas who may need more educational interventions. Initiatives like POG play a critical role in the education of MOs and the integration of big data clinical genomics into cancer care.
Methods: The authors conducted a survey of MOs from British Columbia, Canada (n = 31, 52.5% response rate),who are actively involved in a clinical genomics trial called Personalized Onco-Genomics (POG). The authors also measured MOs’ level of genomic knowledge and attitudes about clinical genomics in cancer medicine.
Results: The findings show a low to moderate level of genomic literacy among MOs. MOs located outside theVancouver area (the major urban center) reported less knowledge about new genetics technologies compared to those located in the major metropolitan area (26.7 vs 73.3%, P < 0.07, Fisher exact test). Forty-two percent of all MOs thought medical training programs do not offer enough genomic training. The majority of the respondents thought genomics will have major impact on drug discovery (67.7%), and treatment selection (58%) in the next5 years. They also thought the major challenges are cost (61.3%), patient genomic literacy (48.3%), and clinical utility of genomics (42%).
Conclusions: The data suggest a high need to increase genomic literacy among MOs and other doctors in medical school training programs and beyond, especially to physicians in regional areas who may need more educational interventions. Initiatives like POG play a critical role in the education of MOs and the integration of big data clinical genomics into cancer care.