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- research-articleFebruary 2023
Fused deep learning paradigm for the prediction of o6-methylguanine-DNA methyltransferase genotype in glioblastoma patients: A neuro-oncological investigation
- Sanjay Saxena,
- Biswajit Jena,
- Bibhabasu Mohapatra,
- Neha Gupta,
- Manudeep Kalra,
- Mario Scartozzi,
- Luca Saba,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 153, Issue Chttps://doi.org/10.1016/j.compbiomed.2022.106492Abstract BackgroundThe O6-methylguanine-DNA methyltransferase (MGMT) is a deoxyribonucleic acid (DNA) repairing enzyme that has been established as an essential clinical brain tumor biomarker for Glioblastoma Multiforme (GBM). Knowing the status of MGMT ...
Highlights- The proposed study aims to provide solutions for building an efficient predictive model of MGMT for GBM patients using deep radiomics features obtained from mp-MRI with the end-to-end ResNet-18 3D and FDL imaging signatures.
- The hand-...
- research-articleNovember 2022
Deep learning artificial intelligence framework for multiclass coronary artery disease prediction using combination of conventional risk factors, carotid ultrasound, and intraplaque neovascularization
- Amer M. Johri,
- Krishna V. Singh,
- Laura E. Mantella,
- Luca Saba,
- Aditya Sharma,
- John R. Laird,
- Kumar Utkarsh,
- Inder M. Singh,
- Suneet Gupta,
- Manudeep S. Kalra,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 150, Issue Chttps://doi.org/10.1016/j.compbiomed.2022.106018Abstract ObjectiveCardiovascular disease (CVD) is a major healthcare challenge and therefore early risk assessment is vital. Previous assessment techniques use either “conventional CVD risk calculators (CCVRC)” or machine learning (ML) paradigms. These ...
- research-articleOctober 2022
Far wall plaque segmentation and area measurement in common and internal carotid artery ultrasound using U-series architectures: An unseen Artificial Intelligence paradigm for stroke risk assessment
Computers in Biology and Medicine (CBIM), Volume 149, Issue Chttps://doi.org/10.1016/j.compbiomed.2022.106017AbstractStroke risk assessment using deep learning (DL) requires automated, accurate, and real-time risk assessment while ensuring compact model size. Previous DL paradigms suffered from challenges like memory size, low speed, and complex in nature ...
Highlights- Stroke Risk assessment system in UNet-based segmentation.
- Three new HDL models: Inception-UNet, Squeeze-UNet, and Fractal-UNet.
- HDL is benchmarked against four SDL models: UNet, UNet+, UNet++ and UNet3P.
- HDL models show low ...
- research-articleAugust 2022
NeoAI 1.0: Machine learning-based paradigm for prediction of neonatal and infant risk of death
Computers in Biology and Medicine (CBIM), Volume 147, Issue Chttps://doi.org/10.1016/j.compbiomed.2022.105639Abstract BackgroundThe Neonatal mortality rate in the United States is 3.8 deaths per 1000 live births, which is comparably higher than other nations.
PurposeThe aim of the proposed study is to design and develop Artificial Intelligence (AI) models (...
Highlights
- Developed neonatal and infant risk of death prediction paradigm using artificial intelligence.
- Implemented machine learning on a dataset containing birth records of 15.8 million patients.
- Used four different machine learning ...
- research-articleJuly 2022
Eight pruning deep learning models for low storage and high-speed COVID-19 computed tomography lung segmentation and heatmap-based lesion localization: A multicenter study using COVLIAS 2.0
- Mohit Agarwal,
- Sushant Agarwal,
- Luca Saba,
- Gian Luca Chabert,
- Suneet Gupta,
- Alessandro Carriero,
- Alessio Pasche,
- Pietro Danna,
- Armin Mehmedovic,
- Gavino Faa,
- Saurabh Shrivastava,
- Kanishka Jain,
- Harsh Jain,
- Tanay Jujaray,
- Inder M. Singh,
- Monika Turk,
- Paramjit S. Chadha,
- Amer M. Johri,
- Narendra N. Khanna,
- Sophie Mavrogeni,
- John R. Laird,
- David W. Sobel,
- Martin Miner,
- Antonella Balestrieri,
- Petros P. Sfikakis,
- George Tsoulfas,
- Durga Prasanna Misra,
- Vikas Agarwal,
- George D. Kitas,
- Jagjit S. Teji,
- Mustafa Al-Maini,
- Surinder K. Dhanjil,
- Andrew Nicolaides,
- Aditya Sharma,
- Vijay Rathore,
- Mostafa Fatemi,
- Azra Alizad,
- Pudukode R. Krishnan,
- Rajanikant R. Yadav,
- Frence Nagy,
- Zsigmond Tamás Kincses,
- Zoltan Ruzsa,
- Subbaram Naidu,
- Klaudija Viskovic,
- Manudeep K. Kalra,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 146, Issue Chttps://doi.org/10.1016/j.compbiomed.2022.105571Abstract BackgroundCOVLIAS 1.0: an automated lung segmentation was designed for COVID-19 diagnosis. It has issues related to storage space and speed. This study shows that COVLIAS 2.0 uses pruned AI (PAI) networks for improving both storage and speed, ...
Highlights
- Eight evolutional algorithms (EA) based on Deep Learning for reduced storage and high speed.
- Multicenter study with 9,000 CT slices.
- COVID-19 based CT lung segmentation and lesion localization.
- Benchmarking against the EA ...
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- review-articleApril 2022
An artificial intelligence framework and its bias for brain tumor segmentation: A narrative review
Computers in Biology and Medicine (CBIM), Volume 143, Issue Chttps://doi.org/10.1016/j.compbiomed.2022.105273Abstract BackgroundArtificial intelligence (AI) has become a prominent technique for medical diagnosis and represents an essential role in detecting brain tumors. Although AI-based models are widely used in brain lesion segmentation (BLS), understanding ...
Highlights- PRISMA search strategy and statistical distributions for brain tumor segmentation (BTS).
- Comparison between different AI models, its qualitative and quantitative analysis.
- Ranking Score Method for Risk-of-bias (RoB) estimation in ...
- review-articleMarch 2022
Understanding the bias in machine learning systems for cardiovascular disease risk assessment: The first of its kind review
- Jasjit S. Suri,
- Mrinalini Bhagawati,
- Sudip Paul,
- Athanasios Protogeron,
- Petros P. Sfikakis,
- George D. Kitas,
- Narendra N. Khanna,
- Zoltan Ruzsa,
- Aditya M. Sharma,
- Sanjay Saxena,
- Gavino Faa,
- Kosmas I. Paraskevas,
- John R. Laird,
- Amer M. Johri,
- Luca Saba,
- Manudeep Kalra
Computers in Biology and Medicine (CBIM), Volume 142, Issue Chttps://doi.org/10.1016/j.compbiomed.2021.105204Abstract BackgroundArtificial Intelligence (AI), in particular, machine learning (ML) has shown promising results in coronary artery disease (CAD) or cardiovascular disease (CVD) risk prediction. Bias in ML systems is of great interest due to its over-...
Highlights
- Risk-of-Bias (RoB) in Machine Learning (ML) studies for cardiovascular disease (CVD) risk prediction using 46 AI attributes.
- Mean score computed, ranked, plotted using slope method, and two cutoffs established, and evaluating the three ...
- research-articleFebruary 2022
A hybrid deep learning paradigm for carotid plaque tissue characterization and its validation in multicenter cohorts using a supercomputer framework
- Sanagala S. Skandha,
- Andrew Nicolaides,
- Suneet K. Gupta,
- Vijaya K. Koppula,
- Luca Saba,
- Amer M. Johri,
- Manudeep S. Kalra,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 141, Issue Chttps://doi.org/10.1016/j.compbiomed.2021.105131Abstract BackgroundEarly and automated detection of carotid plaques prevents strokes, which are the second leading cause of death worldwide according to the World Health Organization. Artificial intelligence (AI) offers automated solutions for plaque ...
Highlights
- Fusion of deep learning with ten kinds of machine learning classifiers.
- Fusion of Inception and ResNet.
- Three kinds of loss functions such as cross-entropy loss, hinge loss, or mean-squared-error loss, and hypothesis was validated.
- research-articleJanuary 2022
A machine learning framework for risk prediction of multi-label cardiovascular events based on focused carotid plaque B-Mode ultrasound: A Canadian study
Computers in Biology and Medicine (CBIM), Volume 140, Issue Chttps://doi.org/10.1016/j.compbiomed.2021.105102Abstract MotivationMachine learning (ML) algorithms can provide better cardiovascular event (CVE) prediction. However, ML algorithms are mostly explored for predicting a single CVE at a time. The objective of this study is to design ...
Highlights- The first study, which predicts multi-label cardiovascular events using the machine learning (ML) paradigm.
- review-articleOctober 2021
Artificial intelligence-based hybrid deep learning models for image classification: The first narrative review
Computers in Biology and Medicine (CBIM), Volume 137, Issue Chttps://doi.org/10.1016/j.compbiomed.2021.104803Abstract BackgroundArtificial intelligence (AI) has served humanity in many applications since its inception. Currently, it dominates the imaging field—in particular, image classification. The task of image classification became ...
Highlights- Use of PRISMA model for search strategy.
- Three types of hybrid deep learning ...
- research-articleSeptember 2021
Hybrid deep learning segmentation models for atherosclerotic plaque in internal carotid artery B-mode ultrasound
Computers in Biology and Medicine (CBIM), Volume 136, Issue Chttps://doi.org/10.1016/j.compbiomed.2021.104721AbstractThe automated and accurate carotid plaque segmentation in B-mode ultrasound (US) is an essential part of stroke risk stratification. Previous segmented methods used AtheroEdge™ 2.0 (AtheroPoint™, Roseville, CA) for the common carotid ...
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Highlights- Carotid plaque and wall segmentation and quantification using ten types of solo and hybrid deep learning models.
- review-articleApril 2024
A narrative review on characterization of acute respiratory distress syndrome in COVID-19-infected lungs using artificial intelligence
- Jasjit S. Suri,
- Sushant Agarwal,
- Suneet K. Gupta,
- Anudeep Puvvula,
- Mainak Biswas,
- Luca Saba,
- Arindam Bit,
- Gopal S. Tandel,
- Mohit Agarwal,
- Anubhav Patrick,
- Gavino Faa,
- Inder M. Singh,
- Ronald Oberleitner,
- Monika Turk,
- Paramjit S. Chadha,
- Amer M. Johri,
- J. Miguel Sanches,
- Narendra N. Khanna,
- Klaudija Viskovic,
- Sophie Mavrogeni,
- John R. Laird,
- Gyan Pareek,
- Martin Miner,
- David W. Sobel,
- Antonella Balestrieri,
- Petros P. Sfikakis,
- George Tsoulfas,
- Athanasios Protogerou,
- Durga Prasanna Misra,
- Vikas Agarwal,
- George D. Kitas,
- Puneet Ahluwalia,
- Jagjit Teji,
- Mustafa Al-Maini,
- Surinder K. Dhanjil,
- Meyypan Sockalingam,
- Ajit Saxena,
- Andrew Nicolaides,
- Aditya Sharma,
- Vijay Rathore,
- Janet N.A. Ajuluchukwu,
- Mostafa Fatemi,
- Azra Alizad,
- Vijay Viswanathan,
- P.K. Krishnan,
- Subbaram Naidu
Computers in Biology and Medicine (CBIM), Volume 130, Issue Chttps://doi.org/10.1016/j.compbiomed.2021.104210AbstractCOVID-19 has infected 77.4 million people worldwide and has caused 1.7 million fatalities as of December 21, 2020. The primary cause of death due to COVID-19 is Acute Respiratory Distress Syndrome (ARDS). According to the World Health ...
Highlights- The review presents the PRISMA model for ARDS-based studies and eight stages of pathophysiology in ARDS due to COVID-19.
- Selection of comorbidity studies, and their statistical distribution in ARDS framework.
- Classification of the ...
- review-articleNovember 2020
Artificial intelligence framework for predictive cardiovascular and stroke risk assessment models: A narrative review of integrated approaches using carotid ultrasound
- Ankush D. Jamthikar,
- Deep Gupta,
- Luca Saba,
- Narendra N. Khanna,
- Klaudija Viskovic,
- Sophie Mavrogeni,
- John R. Laird,
- Naveed Sattar,
- Amer M. Johri,
- Gyan Pareek,
- Martin Miner,
- Petros P. Sfikakis,
- Athanasios Protogerou,
- Vijay Viswanathan,
- Aditya Sharma,
- George D. Kitas,
- Andrew Nicolaides,
- Raghu Kolluri,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 126, Issue Chttps://doi.org/10.1016/j.compbiomed.2020.104043Abstract Recent findingsCardiovascular disease (CVD) is the leading cause of mortality and poses challenges for healthcare providers globally. Risk-based approaches for the management of CVD are becoming popular for recommending ...
Highlights- Cardiovascular disease (CVD) risk prediction algorithms are becoming popular for recommending treatment plans for asymptomatic individuals.
- research-articleMay 2019
Ranking of stroke and cardiovascular risk factors for an optimal risk calculator design: Logistic regression approach
- Elisa Cuadrado-Godia,
- Ankush D. Jamthikar,
- Deep Gupta,
- Narendra N. Khanna,
- Tadashi Araki,
- Md Maniruzzaman,
- Luca Saba,
- Andrew Nicolaides,
- Aditya Sharma,
- Tomaz Omerzu,
- Harman S. Suri,
- Ajay Gupta,
- Sophie Mavrogeni,
- Monika Turk,
- John R. Laird,
- Athanasios Protogerou,
- Petros Sfikakis,
- George D. Kitas,
- Vijay Viswanathan,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 108, Issue CPages 182–195https://doi.org/10.1016/j.compbiomed.2019.03.020Abstract PurposeConventional cardiovascular risk factors (CCVRFs) and carotid ultrasound image-based phenotypes (CUSIP) are independently associated with long-term risk of cardiovascular (CV) disease. In this study, 26 ...
- research-articleDecember 2017
Web-based accurate measurements of carotid lumen diameter and stenosis severity
- Luca Saba,
- Sumit K. Banchhor,
- Narendra D. Londhe,
- Tadashi Araki,
- John R. Laird,
- Ajay Gupta,
- Andrew Nicolaides,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 91, Issue CPages 306–317https://doi.org/10.1016/j.compbiomed.2017.10.022BackgroundThis pilot study presents a completely automated, novel, smart, cloud-based, point-of-care system for (a) carotid lumen diameter (LD); (b) stenosis severity index (SSI) and (c) total lumen area (TLA) measurement using B-mode ultrasound. The ...
- research-articleDecember 2017
Wall-based measurement features provides an improved IVUS coronary artery risk assessment when fused with plaque texture-based features during machine learning paradigm
- Sumit K. Banchhor,
- Narendra D. Londhe,
- Tadashi Araki,
- Luca Saba,
- Petia Radeva,
- John R. Laird,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 91, Issue CPages 198–212https://doi.org/10.1016/j.compbiomed.2017.10.019BackgroundPlanning of percutaneous interventional procedures involves a pre-screening and risk stratification of the coronary artery disease. Current screening tools use stand-alone plaque texture-based features and therefore lack the ability to ...
- research-articleOctober 2017
Lung disease stratification using amalgamation of Riesz and Gabor transforms in machine learning framework
- Joel C.M. Than,
- Luca Saba,
- Norliza M. Noor,
- Omar M. Rijal,
- Rosminah M. Kassim,
- Ashari Yunus,
- Harman S. Suri,
- Michele Porcu,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 89, Issue CPages 197–211https://doi.org/10.1016/j.compbiomed.2017.08.014Lung disease risk stratification is important for both diagnosis and treatment planning, particularly in biopsies and radiation therapy. Manual lung disease risk stratification is challenging because of: (a) large lung data sizes, (b) inter- and intra-...
- research-articleMay 2017
Well-balanced system for coronary calcium detection and volume measurement in a low resolution intravascular ultrasound videos
- Sumit K. Banchhor,
- Narendra D. Londhe,
- Tadashi Araki,
- Luca Saba,
- Petia Radeva,
- John R. Laird,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 84, Issue CPages 168–181https://doi.org/10.1016/j.compbiomed.2017.03.026BackgroundAccurate and fast quantitative assessment of calcium volume is required during the planning of percutaneous coronary interventions procedures. Low resolution in intravascular ultrasound (IVUS) coronary videos poses a threat to calcium ...
- research-articleJanuary 2017
Stroke Risk Stratification and its Validation using Ultrasonic Echolucent Carotid Wall Plaque Morphology
- Tadashi Araki,
- Pankaj K. Jain,
- Harman S. Suri,
- Narendra D. Londhe,
- Nobutaka Ikeda,
- Ayman El-Baz,
- Vimal K. Shrivastava,
- Luca Saba,
- Andrew Nicolaides,
- Shoaib Shafique,
- John R. Laird,
- Ajay Gupta,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 80, Issue CPages 77–96https://doi.org/10.1016/j.compbiomed.2016.11.011Stroke risk stratification based on grayscale morphology of the ultrasound carotid wall has recently been shown to have a promise in classification of high risk versus low risk plaque or symptomatic versus asymptomatic plaques. In previous studies, this ...
- research-articleAugust 2016
Accurate cloud-based smart IMT measurement, its validation and stroke risk stratification in carotid ultrasound
- Luca Saba,
- Sumit K. Banchhor,
- Harman S. Suri,
- Narendra D. Londhe,
- Tadashi Araki,
- Nobutaka Ikeda,
- Klaudija Viskovic,
- Shoaib Shafique,
- John R. Laird,
- Ajay Gupta,
- Andrew Nicolaides,
- Jasjit S. Suri
Computers in Biology and Medicine (CBIM), Volume 75, Issue CPages 217–234https://doi.org/10.1016/j.compbiomed.2016.06.010This study presents AtheroCloudź - a novel cloud-based smart carotid intima-media thickness (cIMT) measurement tool using B-mode ultrasound for stroke/cardiovascular risk assessment and its stratification. This is an anytime-anywhere clinical tool for ...