Article

Learning context cues for synapse segmentation in EM volumes

Authors:

Carlos Becker,

Karim Ali,

Graham Knott,

Pascal FuaAuthors Info & Claims

MICCAI'12: Proceedings of the 15th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part I

Pages 585 - 592

https://doi.org/10.1007/978-3-642-33415-3_72

Published: 01 October 2012 Publication History

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Abstract

We present a new approach for the automated segmentation of excitatory synapses in image stacks acquired by electron microscopy. We rely on a large set of image features specifically designed to take spatial context into account and train a classifier that can effectively utilize cues such as the presence of a nearby post-synaptic region. As a result, our algorithm successfully distinguishes synapses from the numerous other organelles that appear within an EM volume, including those whose local textural properties are relatively similar. This enables us to achieve very high detection rates with very few false positives.

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Cited By

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Heinrich LFunke JPape CNunez-Iglesias JSaalfeld S(2018)Synaptic Cleft Segmentation in Non-isotropic Volume Electron Microscopy of the Complete Drosophila BrainMedical Image Computing and Computer Assisted Intervention – MICCAI 201810.1007/978-3-030-00934-2_36(317-325)Online publication date: 16-Sep-2018
https://dl.acm.org/doi/10.1007/978-3-030-00934-2_36
Kreshuk AFunke JCardona AHamprecht F(2015)Who Is Talking to WhomProceedings of the 18th International Conference on Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2015 - Volume 934910.1007/978-3-319-24553-9_81(661-668)Online publication date: 5-Oct-2015
https://dl.acm.org/doi/10.1007/978-3-319-24553-9_81

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Published In

MICCAI'12: Proceedings of the 15th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part I

October 2012

746 pages

ISBN:9783642334146

Editors:
Nicholas Ayache
Inria Sophia Antipolis, Project Team Asclepios, Sophia-Antipolis, France
,
Hervé Delingette
Inria Sophia Antipolis, Project Team Asclepios, Sophia-Antipolis, France
,
Polina Golland
MIT, CSAIL, Cambridge,, MA, France
,
Kensaku Mori
Information and Communication, Nagoya University, Headquarters, Nagoya, Japan

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Springer-Verlag

Berlin, Heidelberg

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Published: 01 October 2012

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Heinrich LFunke JPape CNunez-Iglesias JSaalfeld S(2018)Synaptic Cleft Segmentation in Non-isotropic Volume Electron Microscopy of the Complete Drosophila BrainMedical Image Computing and Computer Assisted Intervention – MICCAI 201810.1007/978-3-030-00934-2_36(317-325)Online publication date: 16-Sep-2018
https://dl.acm.org/doi/10.1007/978-3-030-00934-2_36
Kreshuk AFunke JCardona AHamprecht F(2015)Who Is Talking to WhomProceedings of the 18th International Conference on Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2015 - Volume 934910.1007/978-3-319-24553-9_81(661-668)Online publication date: 5-Oct-2015
https://dl.acm.org/doi/10.1007/978-3-319-24553-9_81

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