- İstanbul Yeni Yüzyıl Üniversitesi
Amaç: Bu çalışmanın amacı sensörinöral işitme kaybı olan yetişkin hastalarda kümelenme analizi ile odyogram konfigürasyonlarının yaygınlığını araştırmaktır. Gereç ve Yöntem: Çalışmamıza özel bir hastanenin KBB polikliniğine işitme kaybı... more
Amaç: Bu çalışmanın amacı sensörinöral işitme kaybı olan yetişkin hastalarda kümelenme analizi ile odyogram konfigürasyonlarının yaygınlığını araştırmaktır. Gereç ve Yöntem: Çalışmamıza özel bir hastanenin KBB polikliniğine işitme kaybı ile başvuran ve saf ses odyometrisi sonucunda sensörinöral tipte işitme kaybı olan 97 yetişkin hasta dahil edildi. Çalışmaya dahil edilen hastaların sağ kulak hava iletim eşikleri esas alındı ve odyolojik veriler aynı cihaz ve aynı odyometrist tarafından ölçüldü. Saf ses işitme eşiklerine göre konfigürasyon türleri kategorize edildi. Bulgular: İncelenen 97 yetişkinin sağ kulak odyometri verileri küme analizi yapıldığında, 7 farklı konfigürasyon tipi bulundu. En sık görülen konfigürasyon slopping %35. 05 olarak bulundu. Bunu sırasıyla diğer, flat, ski-slope, notched, rising, corner tip konfigürasyonlu odyogramlar izledi. Tartışma ve Sonuç: Çalışmada sensörinöral işitme kaybı olan yetişkinler arasında kabul edilen 7 farklı konfigürasyon arasında en yaygın konfigürasyon tipinin ‘slopping’ olduğu görülmektedir. Klinik yararlılık açısından, işitme cihazı üreticilerinin konfigürasyon tipi seçeneğini işitme cihazı seçim programına eklemeleri önemli bir katkı olabilir.
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Vertigo kişinin veya çevresinin sanal bir hareket hissidir. Be- nign paroksismal pozisyonel vertigo (BPPV) yerçekimi ile ilgili olarak başın pozisyon değişiklikleri sonucu ortaya çıkar. BPPV’ye kulak, burun ve boğaz (KBB) kliniklerinde... more
Vertigo kişinin veya çevresinin sanal bir hareket hissidir. Be- nign paroksismal pozisyonel vertigo (BPPV) yerçekimi ile ilgili olarak başın pozisyon değişiklikleri sonucu ortaya çıkar. BPPV’ye kulak, burun ve boğaz (KBB) kliniklerinde sıkça karşılaşılır. BPPV’nin, utriküler makuladaki yerinden çıkmış serbest hareket eden otolit fragmanları tarafından oluşturuldu- ğu düşünülmektedir. BPPV’nin nistagmusa sebep olan diğer hastalıklardan en önemli farkı, başın karşı yöne çevrilmesine bağlı olarak nistagmus yönünün değişmesidir. BPPV için en yaygın tedaviler yeniden konumlandırma manevralarıdır. Etkilenen her kanala özgü manevralar vardır. Posterior kanal BPPV’sinde Epley veya Semont manevrası kullanılarak tedavi edilebilir. Lateral kanal BPPV’si için Lempert'in (barbekü) veya Gufoni'nin manevraları etkilidir. Anteriror kanal BPPV'si için Epley'leri (etkilenen taraftan başlayarak) veya Yacovino ma- nevrası yapılır. İlaç tedavisi ve ameliyat bu hastalarda nadiren kullanılmaktadır.
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Research Interests: Psychology and Tinnitus
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Taking medical history, physical examination, and performing some in vivo and in vitro tests are necessary for the diagnosis of allergy. Skin prick test (SPT) is considered as the standard method and first-line approach for the detection... more
Taking medical history, physical examination, and performing some in vivo and in vitro tests are necessary for the diagnosis of allergy. Skin prick test (SPT) is considered as the standard method and first-line approach for the detection of allergic sensitization. Although mainly SPT is used for the detection of allergic sensitization, intradermal skin test (IDST) may be necessary, especially in patients with a negative SPT result. IDST is quite safe; however, is nowadays seldom used for detection of inhalant allergy and its value remains controversial. We aimed to investigate whether IDST is useful and necessary in diagnosis of respiratory allergies or not. This study involved 4223 patients with allergic rhinitis (AR) and/or bronchial asthma (BA). SPT results were positive in 2419 patients (57%) and negative in 1804 (43%). IDST was applied to 344 patients with marked allergic symptoms and with negative SPT results. Out of 344 patients, 152 (44%) showed allergic sensitization to IDS...
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Objective: The purpose of the present study was to investigate the relationship of sinonasal anatomic variations (SAVs) with maxillary sinus retention cysts (RCs) on paranasal sinus tomography. Methods: Our study included 202 patients who... more
Objective: The purpose of the present study was to investigate the relationship of sinonasal anatomic variations (SAVs) with maxillary sinus retention cysts (RCs) on paranasal sinus tomography. Methods: Our study included 202 patients who applied to the ENT outpatient clinic with fascial pain, nasal obstruction and postnasal drip complaints between September 2014 and February 2016 and underwent CT of paranasal sinus on coronal plane. The patients who had maxillary RCs in their CT scan comprised the study group while the patients who did not have RCs in their CT scan comprised the control group. The CT scans of these two groups were examined and recorded for the SAVs. The statistical analysis of the SAVs for these two groups was conducted using the Mann-Whitney U test. Results: The presence of septal deviation from SAVs and pneumatized uncinate in patients found to have maxillary sinus retention cyst was considered statistically significant (p<0.05). The sex in patients with right...
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BACKGROUND Osteoporosis is a disease characterized by an increase in bone fragility as a result of decreased bone mass and weakening of the bone structure. There are studies on the relationship between osteoporosis and hearing and balance... more
BACKGROUND Osteoporosis is a disease characterized by an increase in bone fragility as a result of decreased bone mass and weakening of the bone structure. There are studies on the relationship between osteoporosis and hearing and balance system. The goal of this study was to compare the proliferation and osteogenesis induction properties of mesenchymal stem cells derived from healthy and osteoporotic individuals to better understand the healing properties of Korean red ginseng (KRG) and Panax ginseng-Avena Sativa-Tribulus Terrestris mixture (PAT). MATERIALS AND METHODS Osteoporotic and healthy MSCs were isolated successfully in culture conditions. The proliferation levels of cells treated with different doses of KRG and PAT were compared by Water-Soluble Tetrazolium-1 (WST-1) assay. Alkaline phosphatase (ALP) assay was performed by selecting the most effective KRG dose in proliferation. RESULTS Morphology of isolated cells and the expression of cell surface antigens have been detec...
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Amaç: Bu çalışmada anestezi ve reanimasyon uzmanlarına; birlikte çalıştıkları anestezi teknisyen/teknikerlerinin klinik ve teknik açıdan olası eksikliklerini ortaya koymak, ameliyathane haricinde anestezi teknisyen/teknikerlerine ihtiyaç... more
Amaç: Bu çalışmada anestezi ve reanimasyon uzmanlarına; birlikte çalıştıkları anestezi teknisyen/teknikerlerinin klinik ve teknik açıdan olası eksikliklerini ortaya koymak, ameliyathane haricinde anestezi teknisyen/teknikerlerine ihtiyaç duyulan birimler ve verilebilecek sorumluluklar varsa tespit etmek amacıyla bir anket çalışması yapılmıştır. Yöntem: Üniversite hastanesi, eğitim ve araştırma hastanesi, devlet hastanesi ve özel hastaneler olmak üzere Türkiye’nin farklı illerindeki hastanelerde görev yapmakta olan 170 anestezi ve reanimasyon uzmanının görüşleri anket soruları aracılığıyla elektronik ortamda alınmıştır. Elde edilen verilerin analizinde IBM Microsoft SPSS 24.0 paket programı kullanılmıştır. Yapılan istatistiksel analizler; frekans, faktör, korelasyon, T-testi ve ANOVA analizleridir. Bulgular: Çalışmaya katılan anestezi hekimlerinin % 60‘ı kadın, % 40’ı ise erkektir. Katılımcıların % 42’si 28-38 yaş aralığında, % 44’ü 39-50 yaş aralığında, % 14’ü ise 51-73 yaş aralığın...
Research Interests: Greenwich and Gynecology
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Objective: The purpose of the present study was to investigate whether high platelet distribution width (PDW) levels correlated with nasal polyps or not. Methods: The study was performed retrospectively in 99 patients who underwent... more
Objective: The purpose of the present study was to investigate whether high platelet distribution width (PDW) levels correlated with nasal polyps or not. Methods: The study was performed retrospectively in 99 patients who underwent endoscopic sinus surgery for nasal polyposis. Data were collected from the routine preoperative hemograms of the patients. The study group was compared with an age- and sex-matched control group including 150 healthy subjects. The Mann-Whitney U test was used to compare the results of the two groups. Results: The PDW level for the study group was 14.49±2.08, while for the control group it was 13.76±2.14. The PDW levels of the study group were higher than those of the control group, and this difference was statistically significant (p<0.05). Conclusion: The rise of the PDW levels in patients with nasal polyposis should be investigated for the diagnostic value, and the rise of PDW levels in patients with nasal polyposis may be used for its diagnostic eva...
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AMAC:Sadece burun tikanikligi sikayeti olan hastalarda yapilan septoplasti operasyonundan once burun tikanikligina yol acabilen anatomik varyasyondan suphe duyulan her hastaya paranazal sinus bilgisayarli tomografi (BT) cekilmesinin... more
AMAC:Sadece burun tikanikligi sikayeti olan hastalarda yapilan septoplasti operasyonundan once burun tikanikligina yol acabilen anatomik varyasyondan suphe duyulan her hastaya paranazal sinus bilgisayarli tomografi (BT) cekilmesinin onemi, bir vaka uzerinde gosterildi. Birden cok sinonazal anatomik varyasyonu bir arada bulunduran bu olgumuzda, hem anatomik varyasyonlari gostermek istedik; hem de septum deviasyonu operasyonlarindan once suphe duyulan vakalarda paranazal sinus tomografisinin cekilmesinin onemine vurgu yaptik. OLGUNUN OZELLIKLERI:23 yasinda erkek hasta, cocukluk yillarindan beri burun tikanikligi sikayeti ile Şubat 2015 de klinigimize basvurdu. Hastanin sinuzite dair bas agrisi, geniz akintisi sikâyeti yoktu. Muayenede anterior rinoskopide septum deviasyonu (SD) ve sagda orta konka buyuk olarak goruldu. Dekonjestana ragmen konka kuculmeyince, goruntulenen paranazal sinus BT tetkikinde sol maksiller sinuste 2 cm boyutunda retansiyon kisti goruldu. Etmoid, frontal, sag m...
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一、引言 二十世纪七十年代末、八十年代初，美国著名语言学家克拉申（Krashen）提出的“监控理论”是第二语言习得研究中“最全面，最可接受的一种理论”。克拉申“监控理论”的核心是五项基本假说：语言习得与学习假说、监控假说、自然顺序假说、语言输入假说和情感过滤假说。
The aim of the present study was to investigate inhalant allergen sensitivity in adult patients with allergic rhinitis (AR) and to compare allergen sensitization based on age and sex under ecological conditions of urban areas
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Research Interests: Medicine and Biomedical
Amaç: Bu çalışma ile ülkemizdeki Kulak Burun Boğaz (KBB) uzman ve asistanlarının sağladığı geri bildirim (anket) üzerinden kök hücre kullanımına ilişkin düşüncelerini ve yaklaşımlarını öğrenmek amaçlanmıştır. Gereç ve Yöntem: KBB... more
Amaç: Bu çalışma ile ülkemizdeki Kulak Burun Boğaz (KBB) uzman ve asistanlarının sağladığı geri bildirim (anket) üzerinden kök hücre kullanımına ilişkin düşüncelerini ve yaklaşımlarını öğrenmek amaçlanmıştır. Gereç ve Yöntem: KBB uzmanları ve asistanların kök hücre konusunda bilgi ve görüşlerini öğrenmek amacıyla bir anket çalışması planlandı. Çalışma için gerekli izin Türk Kulak Burun Boğaz ve Baş Boyun Cerrahisi Derneği (kbbbbcder) bilimsel kurulundan alındı ve anket formu derneğe kayıtlı olan 5500 üyeye e-posta yoluyla gönderildi. Ankete, çevrimiçi olarak 74 KBB uzmanı ve 48 KBB asistanı toplam 122 kişi geri dönüş yaparak katılmıştır. Bulgular: Araştırmada uzman ve yardımcı katılımcı, KBB hekimlerinin %90'dan fazlasının kök hücre tedavilerinin kan hastalıklarında kullanımı konusunda bilgi sahibi olduğunu belirtti. Bununla birlikte, işitme kaybı ve diğer KBB uygulamalarındaki kök hücre kullanımına ilişkin yeterli bilgiye sahip olmadıklarını ve eğitim programlarına katılmadıkla...
Malignant mucosal melanoma is an uncommon disease with a low rate of survival. Malignancies of nasal mucosa which usually presents with nasal obstruction, epistaxis and back drip are difficult to treat and often have poor prognosis. The... more
Malignant mucosal melanoma is an uncommon disease with a low rate of survival. Malignancies of nasal mucosa which usually presents with nasal obstruction, epistaxis and back drip are difficult to treat and often have poor prognosis. The present case had presented to our clinic with classic symptoms and diagnostic findings of nasal polyposis. Consistently, the patient had previously been diagnosed with and treated for nasal polyposis in another ENT clinic. Physical examination, rhinoscopic examination, computed tomography (CT) scan of the head did not reveal any findings which might imply malignant formations. The operation had been planned for nasal polypectomy and taking deep biopsy specimens. The incised mass showed characteristic features of malignant tissues and the pathology report of the biopsy samples revealed that the specimen showed the histological signs of malignancy. Based on physical examination, CT findings and pathology reports the case was diagnosed as nasal mucosal ...
Objectives: We evaluated the results of hearing screening tests performed at our center during the study. Methods: In this descriptive study, 1808 newborns at our center between October 2015 and November 2017 were examined. Hearing... more
Objectives: We evaluated the results of hearing screening tests performed at our center during the study. Methods: In this descriptive study, 1808 newborns at our center between October 2015 and November 2017 were examined. Hearing screening tests were done according to the National Hearing Screening Protocol without discharge from the baby hospital. Results: In this study totally 1808 babies were designated for hearing screening test. According to the hearing screening tests, the percentage of babies who are suspected of hearing loss and referred to the reference center is 0.11%. Conclusion: Early detection of hearing the loss in newborns is important for early treatment. All newborns should be assessed in terms of their risk factors and all those involved in the risk group should be screened. In this respect, treatment of hearing loss children can be started for language and speech development can be achieved.
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Objectives: The purpose of the present study was to investigate whether high platelet distribution width (PDW) levels correlated with nasal polyps. Methods: The study was performed retrospectively in 99 patients who underwent endoscopic... more
Objectives: The purpose of the present study was to investigate whether high platelet distribution width (PDW) levels correlated with nasal polyps. Methods: The study was performed retrospectively in 99 patients who underwent endoscopic sinus surgery for nasal polyposis. Data were collected from the routine preoperative hemograms of the patients. The study group was compared with an ageand sex-matched control group including 99 healthy subjects. The Mann–Whitney U test was used to compare the results of the two groups. Results: The PDW levels of the study group were statistically higher than those of the control group (p=0.041). Conclusion: The rise in the PDW levels in the nasal polyposis group may be explained by allergic inflammation. More detailed studies are needed to confirm this.
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Aim: Since tonsillectomies and/or adenoidectomies performed in the pediatric age group under general anesthesia have a high rate of postoperative nausea and vomiting (PONV), the practice of using prophylactic antiemetic drugs is common.... more
Aim: Since tonsillectomies and/or adenoidectomies performed in the pediatric age group under general anesthesia have a high rate of postoperative nausea and vomiting (PONV), the practice of using prophylactic antiemetic drugs is common. This study aimed to compare the benefits of systemic administration of a low dose of inj. methylprednisolone 1 mg/kg with inj. metoclopramide 0.15 mg/kg IV for the prevention of PONV in children undergoing adenotonsillectomy. Methodology: In this study, the files of children undergone adenotonsillectomy from August 2015 to January 2018 in our hospital were analyzed retrospectively. 408 children aged 4-12 years were included in the study. Patients who were given methylprednisolone 1 mg/kg IV as premedication were placed in Group P, and patients who received metoclopramide 0.15 mg/kg were grouped as Group M. Effects on PONV, vomiting episodes, oral intake time, postoperative analgesic requirement, postoperative respiratory complications, and drug side ...