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Four cases of serious cardiac attacks by autochthonous Trypanosoma cruzi infection from the Brazilian Amazon are reported; three of them occurred in micro-epidemic episodes. The manifestations included sudden fever, myalgia, dyspnea and... more
Four cases of serious cardiac attacks by autochthonous Trypanosoma cruzi infection from the Brazilian Amazon are reported; three of them occurred in micro-epidemic episodes. The manifestations included sudden fever, myalgia, dyspnea and signs of heart failure. Diagnosis was confirmed by specific exams, especially QBC (Quantitative Buffy Coat) and natural xenodiagnosis. Despite treatment with benznidazol, three patients died with serious myocarditis, renal failure and cardiac tamponade. The authors call attention to the emergence of this disease and reveal a previously unknown pathogenicity of T. cruzi strains in this area, added to a non-usual transmission form.
Acute Chagas disease (ACD) is caused by Trypanosoma cruzi. ACD outbreaks due to probable oral transmission occur regularly in small family gatherings that are exposed to contaminated foods. We studied two cohorts of residents on islands... more
Acute Chagas disease (ACD) is caused by Trypanosoma cruzi. ACD outbreaks due to probable oral transmission occur regularly in small family gatherings that are exposed to contaminated foods. We studied two cohorts of residents on islands in the Breves and Bagre municipalities, in July and August 2007, to identify risk factors of transmission and to recommend preventative measures. Of the 25 cases identified in both cohorts, 13 (52%) were men, and the most frequent symptoms were fever (96%),asthenia (80%), myalgia (76%), abdominal pain (64%), retro-orbital pain, headaches and asthma (52%). We recommend detailed investigation of future outbreaks and other studies to better understand and control oral transmission of T. cruzi.
... Sebastião Aldo da Silva Valente + , Vera da Costa Valente, Habib Fraiha Neto. ... New serological studies for anti-T. cruzi antibodies should use more modern antigens, considering the past 20 years of human intervention in the region.... more
... Sebastião Aldo da Silva Valente + , Vera da Costa Valente, Habib Fraiha Neto. ... New serological studies for anti-T. cruzi antibodies should use more modern antigens, considering the past 20 years of human intervention in the region. ... [ Links ]; Naiff RD, Barret TV, Arias JA 1987. ...
... Adelson AA de Souza, Fernando Tobias Silveira, Michael A. Miles, Marinete M. Póvoa, José Aprígio Nunes Lima e Sebastião Aldo S. Valente ... Ao dr. Habib Fraiha Neto, entomologista da IEC pela identificação dos triatomíneos capturados.... more
... Adelson AA de Souza, Fernando Tobias Silveira, Michael A. Miles, Marinete M. Póvoa, José Aprígio Nunes Lima e Sebastião Aldo S. Valente ... Ao dr. Habib Fraiha Neto, entomologista da IEC pela identificação dos triatomíneos capturados. A Sra. ...
Research Interests:
Research Interests: