Research Interests:
Research Interests: Microcirculation, Medicine, Video microscopy, Humans, Capillaries, and 15 moreSeptic Shock, Shock, Female, Animals, Male, Clinical Sciences, Middle Aged, Observer Variation, Adult, Reproducibility of Results, Sensitivity and Specificity, Observational Study, Sus Scrofa, Cross Sectional Studies, and Multicenter Study
Research Interests:
Research Interests: Biomedical Engineering, Microscopy, Rheology, Microcirculation, Near Infrared, and 15 moreMedicine, Microvascular Physiology, Humans, Lasers, Arm, Perfusion, Clinical Sciences, Red blood cell, Reperfusion injury, Linear Regression, Blood Flow Velocity, Nails, Microvessels, Laser Speckle Imaging, and Microvascular
Research Interests: Carbon Dioxide, Medicine, Humans, Child, Hemodynamics, and 15 moreNear Infrared Spectroscopy, INTENSIVE CARE, Perfusion, Body Temperature, Clinical Sciences, Intensive Care Unit, Adult, Blood Flow, Intensive Care Medicine, Oximetry, Indexation, Clinical Signs, Peripheral, Laser Doppler Flowmetry, and Laser Doppler Velocimetry
Aim: To determine whether external leg compression (ELC) around the legs could prevent and restore central hypovolemia induced by head-up tilt (HUT) maneuver. Materials & methods: The dynamic effect of ELC was determined using 50 cm H2O... more
Aim: To determine whether external leg compression (ELC) around the legs could prevent and restore central hypovolemia induced by head-up tilt (HUT) maneuver. Materials & methods: The dynamic effect of ELC was determined using 50 cm H2O inflation pressure. HUT was performed without ELC (control model), with ELC inflated before HUT (prevention model) and after HUT (restore model). Results: The decrease in stroke volume (SV) during the prevention model versus control model was 17 ± 3% versus 27 ± 3%. The restore model increased SV by 24 ± 2%. Similarly, peripheral perfusion measured by perfusion index (PI) and tissue oxygen saturation (STO2) was smaller in the prevention model than in the control model (PI: 65 ± 3% vs 79 ± 2%; STO2: 4 ± 1% vs 9 ± 1%). In the restore model, PI increased by 117 ± 24% and STO2 increased by 3 ± 1%. Conclusion: In this study, inflatable ELC around the legs was able to prevent and restore SV and peripheral perfusion in a model of acute central hypovolemia.