Objective: the aim of this study was to evaluate the oral health impact profile (OHIP-14) of obes... more Objective: the aim of this study was to evaluate the oral health impact profile (OHIP-14) of obese patients and patients submitted to bariatric surgery. Methods: One hundred and twenty-five patients (mean age 38±10 years) were examined in a Public Hospital in São Luis-MA, Brazil. The sample was consisted of 42 volunteers that had been submitted to bariatric surgery at least six months previously, 41 obese patients on the waiting list for this surgery and 42 patients waiting for ambulatory medical care in other sectors (Control). The volunteers were submitted to anamnesis and answered the OHIP-14 questionnaire to assess the perceived impact of oral health on life in seven domains: functional limitation, physical pain, psychological discomfort, physical disability, psychological disability, social disability and Handicap. A final score was obtained for each volunteer and data from obese and bariatric patients were compared with control group by Mann-Whitney test (α=0.05). Results: The...
A single vaccination of Yellow Fever vaccines is believed to confer life-long protection. In this... more A single vaccination of Yellow Fever vaccines is believed to confer life-long protection. In this study, results of vaccinees who received a single dose of 17DD-YF immunization followed over 10 years challenge this premise. YF-neutralizing antibodies, subsets of memory T and B cells as well as cytokine-producing lymphocytes were evaluated in groups of adults before (NVday0) and after (PVday30-45, PVyear1-4, PVyear5-9, PVyear10-11, PVyear12-13) 17DD-YF primary vaccination. YF-neutralizing antibodies decrease significantly from PVyear1-4 to PVyear12-13 as compared to PVday30-45, and the seropositivity rates (PRNT≥2.9Log10mIU/mL) become critical (lower than 90%) beyond PVyear5-9. YF-specific memory phenotypes (effector T-cells and classical B-cells) significantly increase at PVday30-45 as compared to naïve baseline. Moreover, these phenotypes tend to decrease at PVyear10-11 as compared to PVday30-45. Decreasing levels of TNF-α(+) and IFN-γ(+) produced by CD4(+) and CD8(+) T-cells along...
Revista da Sociedade Brasileira de Medicina Tropical, 2002
Anticorpos antipromastigotas vivas de Leishmania (Viannia) braziliensis, detectados pela citometr... more Anticorpos antipromastigotas vivas de Leishmania (Viannia) braziliensis, detectados pela citometria de fluxo, para identificação da infecção ativa na leishmaniose tegumentar americana ... Anti-live Leishmania (Viannia) braziliensis promastigote antibodies, detected by flow ...
Veterinary immunology and immunopathology, Jan 15, 2011
In this study, we summarized the major phenotypic/functional aspects of circulating leukocytes fo... more In this study, we summarized the major phenotypic/functional aspects of circulating leukocytes following canine immunization with Leishvaccine and Leishmune®. Our findings showed that Leishvaccine triggered early changes in the innate immunity (neutrophils and eosinophils) with late alterations on monocytes. Conversely, Leishmune(®) induced early phenotypic changes in both, neutrophils and monocytes. Moreover, Leishvaccine triggered mixed activation-related phenotypic changes on T-cells (CD4+ and CD8+ and B-lymphocytes, whereas Leishmune(®) promoted a selective response, mainly associated with CD8+ T-cell activation. Mixed cytokine profile (IFN-γ/IL-4) was observed in Leishvaccine immunized dogs whereas a selective pro-inflammatory pattern (IFN-γ/NO) was induced by Leishmune® vaccination. The distinct immunological profile triggered by Leishvaccine and Leishmune® may be a direct consequence of the distinct biochemical composition of these immunobiological, i.e. complex versus purifi...
Few studies have been conducted to determine the prevalence of chronic diseases and its impact in... more Few studies have been conducted to determine the prevalence of chronic diseases and its impact in individuals aged 40 years or over in Brazil. The objective of this study is to evaluate the prevalence of some common chronic diseases in the Brazilian subgroup assessed by the PLATINO study using a self-reported survey. A total of 918 individuals (55% women) with a mean age of 54.6 ± 10.9 years were evaluated. The most prevalent diseases were obesity (62.5%), hypertension (39.2%) and gastritis (30.9%). We conclude from this study that there is a high prevalence of chronic diseases in the population over 40 years of age: 88% of the population suffers from a minimum of one disease and 26% of the sample suffers from at least three diseases. We also observed that the number of comorbidities increases with age.
Objective: the aim of this study was to evaluate the oral health impact profile (OHIP-14) of obes... more Objective: the aim of this study was to evaluate the oral health impact profile (OHIP-14) of obese patients and patients submitted to bariatric surgery. Methods: One hundred and twenty-five patients (mean age 38±10 years) were examined in a Public Hospital in São Luis-MA, Brazil. The sample was consisted of 42 volunteers that had been submitted to bariatric surgery at least six months previously, 41 obese patients on the waiting list for this surgery and 42 patients waiting for ambulatory medical care in other sectors (Control). The volunteers were submitted to anamnesis and answered the OHIP-14 questionnaire to assess the perceived impact of oral health on life in seven domains: functional limitation, physical pain, psychological discomfort, physical disability, psychological disability, social disability and Handicap. A final score was obtained for each volunteer and data from obese and bariatric patients were compared with control group by Mann-Whitney test (α=0.05). Results: The...
A single vaccination of Yellow Fever vaccines is believed to confer life-long protection. In this... more A single vaccination of Yellow Fever vaccines is believed to confer life-long protection. In this study, results of vaccinees who received a single dose of 17DD-YF immunization followed over 10 years challenge this premise. YF-neutralizing antibodies, subsets of memory T and B cells as well as cytokine-producing lymphocytes were evaluated in groups of adults before (NVday0) and after (PVday30-45, PVyear1-4, PVyear5-9, PVyear10-11, PVyear12-13) 17DD-YF primary vaccination. YF-neutralizing antibodies decrease significantly from PVyear1-4 to PVyear12-13 as compared to PVday30-45, and the seropositivity rates (PRNT≥2.9Log10mIU/mL) become critical (lower than 90%) beyond PVyear5-9. YF-specific memory phenotypes (effector T-cells and classical B-cells) significantly increase at PVday30-45 as compared to naïve baseline. Moreover, these phenotypes tend to decrease at PVyear10-11 as compared to PVday30-45. Decreasing levels of TNF-α(+) and IFN-γ(+) produced by CD4(+) and CD8(+) T-cells along...
Revista da Sociedade Brasileira de Medicina Tropical, 2002
Anticorpos antipromastigotas vivas de Leishmania (Viannia) braziliensis, detectados pela citometr... more Anticorpos antipromastigotas vivas de Leishmania (Viannia) braziliensis, detectados pela citometria de fluxo, para identificação da infecção ativa na leishmaniose tegumentar americana ... Anti-live Leishmania (Viannia) braziliensis promastigote antibodies, detected by flow ...
Veterinary immunology and immunopathology, Jan 15, 2011
In this study, we summarized the major phenotypic/functional aspects of circulating leukocytes fo... more In this study, we summarized the major phenotypic/functional aspects of circulating leukocytes following canine immunization with Leishvaccine and Leishmune®. Our findings showed that Leishvaccine triggered early changes in the innate immunity (neutrophils and eosinophils) with late alterations on monocytes. Conversely, Leishmune(®) induced early phenotypic changes in both, neutrophils and monocytes. Moreover, Leishvaccine triggered mixed activation-related phenotypic changes on T-cells (CD4+ and CD8+ and B-lymphocytes, whereas Leishmune(®) promoted a selective response, mainly associated with CD8+ T-cell activation. Mixed cytokine profile (IFN-γ/IL-4) was observed in Leishvaccine immunized dogs whereas a selective pro-inflammatory pattern (IFN-γ/NO) was induced by Leishmune® vaccination. The distinct immunological profile triggered by Leishvaccine and Leishmune® may be a direct consequence of the distinct biochemical composition of these immunobiological, i.e. complex versus purifi...
Few studies have been conducted to determine the prevalence of chronic diseases and its impact in... more Few studies have been conducted to determine the prevalence of chronic diseases and its impact in individuals aged 40 years or over in Brazil. The objective of this study is to evaluate the prevalence of some common chronic diseases in the Brazilian subgroup assessed by the PLATINO study using a self-reported survey. A total of 918 individuals (55% women) with a mean age of 54.6 ± 10.9 years were evaluated. The most prevalent diseases were obesity (62.5%), hypertension (39.2%) and gastritis (30.9%). We conclude from this study that there is a high prevalence of chronic diseases in the population over 40 years of age: 88% of the population suffers from a minimum of one disease and 26% of the sample suffers from at least three diseases. We also observed that the number of comorbidities increases with age.
Uploads