Research Interests:
Chlorophytum borivilianum Santapau & Fernandes (Liliaceae) also known as 'Safed Musli' is a traditional rare Indian medicinal herb which has many therapeutic applications in Ayurvedic, Unani, Homeopathic and Allopathic system of... more
Chlorophytum borivilianum Santapau & Fernandes (Liliaceae) also known as 'Safed Musli' is a traditional rare Indian medicinal herb which has many therapeutic applications in Ayurvedic, Unani, Homeopathic and Allopathic system of medicine. Its roots (tubers) are widely used for various therapeutic applications. It is used to cure physical illness and weakness, as an aphrodisiac agent and revitalizer, as general sex tonic, remedy for diabetes, arthritis and increasing body immunity, curative for natal and postnatal problems, for rheumatism and joint pains, increase lactation in feeding mothers, as antimicrobial, anti-inflammatory, antitumor agent, also used in diarrhea, dysentery, gonorrhea, leucorrhea etc. It has spermatogenic property and is found useful in curing impotency, now it is considered as an alternative 'Viagra'. Its root contains steroidal and triterpenoidal saponins, sapogenins and fructans which act as therapeutic agents and play vital role in many thera...
Research Interests:
Saponins are imperative non-volatile chemical compounds valued for several medicinal properties. The pharmaceutical use of saponins for semi-synthesis of steroidal drugs makes it an essential element of life with a diverse range of... more
Saponins are imperative non-volatile chemical compounds valued for several medicinal properties. The pharmaceutical use of saponins for semi-synthesis of steroidal drugs makes it an essential element of life with a diverse range of properties including antimicrobial, insecticidal, haemolytic, aphrodisiac, foaming and emulsification. The tuberous roots of Chlorophytum borivilianum always remains a major source for isolation of saponin. A conventional efficient method was developed for saponin isolation from in-vivo and in-vitro samples of C. borivilianum by delipidization and deproteinization with petroleum ether and chloroform leading to development of a whole new process for saponin isolation. Protocol was tested with saponin confirmatory test followed by thin layer chromatography.
Research Interests:
Ganoderma lucidum (Ling Zhi) is a basidiomycete white rot macrofungus which has been used extensively as "the mushroom of immortality" in China, Japan,... more
Ganoderma lucidum (Ling Zhi) is a basidiomycete white rot macrofungus which has been used extensively as "the mushroom of immortality" in China, Japan, Korea and other Asian countries for 2000 years. A great deal of work has been carried out on therapeutic potential of Ganoderma lucidum. The basidiocarp, mycelia and spores of Ganoderma lucidum contain approximately 400 different bioactive compounds, which mainly include triterpenoids, polysaccharides, nucleotides, sterols, steroids, fatty acids, proteins/peptides and trace elements which has been reported to have a number of pharmacological effects including immunomodulation, anti-atherosclerotic, anti-inflammatory, analgesic, chemo-preventive, antitumor, chemo and radio protective, sleep promoting, antibacterial, antiviral (including anti-HIV), hypolipidemic, anti-fibrotic, hepatoprotective, anti-diabetic, anti-androgenic, anti-angiogenic, anti-herpetic, antioxidative and radical-scavenging, anti-aging, hypoglycemic, estrogenic activity and anti-ulcer properties. Ganoderma lucidum has now become recognized as an alternative adjuvant in the treatment of leukemia, carcinoma, hepatitis and diabetes. The macrofungus is very rare in nature rather not sufficient for commercial exploitation for vital therapeutic emergencies, therefore, the cultivation on solid substrates, stationary liquid medium or by submerged cultivation has become an essential aspect to meet the driving force towards the increasing demands in the international market. Present review focuses on the pharmacological aspects, cultivation methods and bioactive metabolites playing a significant role in various therapeutic applications.
Research Interests: Bioengineering, Pharmacology, Biochemistry, Bioinformatics, Microbiology, and 19 morePharmacy, Food Science, Immunology, Nutrition, Molecular Biology, Computational Biology, Toxicology, Biotechnology, Cancer, Food and Nutrition, Cancer Biology, Polysaccharides, Traditional Chinese Medicine, Humans, Medical Biotechnology, Animals, Ganoderma Lucidum, Current, and Reishi
ABSTRACT The authors expressed a lot of enthusiasm towards the application of M. balsamina proteins for combating HIV/ AIDS but problems associated with toxicities and bioavailability of these proteins limit potential usefulness in such... more
ABSTRACT The authors expressed a lot of enthusiasm towards the application of M. balsamina proteins for combating HIV/ AIDS but problems associated with toxicities and bioavailability of these proteins limit potential usefulness in such therapies. A number of critical animal toxicological and human clinical studies should be carried out. Most of the studies that have been carried so far are inconclusive and requires further authentication before advocating this plant as a “hidden gift of nature”.