The present manuscript summarizes the research, which is currently going on in our department regarding the interaction between negative energy balance (NEB) and fertility in modern high yielding dairy cows. In this work, it has been... more
The present manuscript summarizes the research, which is currently going on in our department regarding the interaction between negative energy balance (NEB) and fertility in modern high yielding dairy cows. In this work, it has been clearly demonstrated that nearly 50% of the recently calved dairy cows suffer from one or another ovarian dysfunc- tion during the preservice postpartum period. Both clinical signs of a significant negative energy balance as well as the occurrence of puerperal disorders were main risk factors to suffer from these ovarian problems. In the following research using repeated ovum pick sessions it was demonstrated that homeorhetic changes of metabo- lites known as typical indicators of the negative energy balance, were reflected in the follicular fluid of the dominant folli- cle during the immediate postpartum period. Based on in vitro experiments it was furthermore shown that these metabo- lites were able to affect bovine granulosa cells at concentrations, ...
Research Interests:
Research Interests:
Glucose is the molecule that drives milk production, and insulin plays a pivotal role in the glucose metabolism of dairy cows. The effect of insulin on the glucose metabolism is regulated by the secretion of insulin by the pancreas and... more
Glucose is the molecule that drives milk production, and insulin plays a pivotal role in the glucose metabolism of dairy cows. The effect of insulin on the glucose metabolism is regulated by the secretion of insulin by the pancreas and the insulin sensitivity of the skeletal muscles, the adipose tissue, and the liver. Insulin resistance may develop as part of physiologic (pregnancy and lactation) and pathologic processes, which may manifest as decreased insulin sensitivity or decreased insulin responsiveness. A good knowledge of the normal physiology of insulin is needed to measure the in vivo insulin resistance of dairy cows.
Research Interests:
Research Interests:
- Cystic ovarian follicles (COF) are an important ovarian dysfunction and a major cause of reproductive failure in dairy cattle. Due to the complexity of the disorder and the heterogeneity of the clinical signs, a clear definition is... more
- Cystic ovarian follicles (COF) are an important ovarian dysfunction and a major cause of reproductive failure in dairy cattle. Due to the complexity of the disorder and the heterogeneity of the clinical signs, a clear definition is lacking. A follicle becomes cystic when it fails to ...
Research Interests:
The respiratory burst activity of polymorphonuclear leucocytes (PMN) was evaluated in eight Holstein cows from 8 weeks before until 6 weeks after calving by chemiluminescence (CL). The CL response started to decrease 1 week before... more
The respiratory burst activity of polymorphonuclear leucocytes (PMN) was evaluated in eight Holstein cows from 8 weeks before until 6 weeks after calving by chemiluminescence (CL). The CL response started to decrease 1 week before parturition, reaching a minimum during ...