The scope of this work was to develop a technique based on the regression method and apply it on a real cooled geometry for measuring its internal heat transfer distribution. The proposed methodology is based upon an already available... more
The scope of this work was to develop a technique based on the regression method and apply it on a real cooled geometry for measuring its internal heat transfer distribution. The proposed methodology is based upon an already available literature approach. For implementation of the methodology, the geometry is initially heated to a known steady temperature, followed by thermal transient, induced by injection of ambient air to its internal cooling system. During the thermal transient, external surface temperature of the geometry is recorded with the help of infrared camera. Then, a numerical procedure based upon a series of transient finite element analyses of the geometry is applied by using the obtained experimental data. The total test duration is divided into time steps, during which the heat flux on the internal surface is iteratively updated to target the measured external surface temperature. The final procured heat flux and internal surface temperature data of each time step i...
Research Interests:
To ensure a passable life span of gas turbine hot gas path components the measurement of metal surface temperature is paramount. Experimental analyses on internally cooled devices are often performed on simplified or scaled up geometries,... more
To ensure a passable life span of gas turbine hot gas path components the measurement of metal surface temperature is paramount. Experimental analyses on internally cooled devices are often performed on simplified or scaled up geometries, which reduces the applicability of the results to the actual real hardware. A more reliable estimation of cooling performance could be obtained if the real engine component is directly studied. To achieve this goal, an experimental campaign is performed to investigate the internal heat transfer distribution of an industrial blade, cooled by means of an internal U-shaped channel. During the experiment the blade is heated to a known temperature, then a coolant is introduced through the internal channel to induce a thermal transient, during which the external surface temperature is measured with the help of an infrared camera. Then a transient thermal finite element simulation is performed with the same boundary and inlet conditions of the experiment....
Phosphorus (P) is an essential macroelement supporting maize productivity and low-P stress is a limiting factor of maize growth and yield. Improving maize plant tolerance to low P through molecular breeding is an effective alternative to... more
Phosphorus (P) is an essential macroelement supporting maize productivity and low-P stress is a limiting factor of maize growth and yield. Improving maize plant tolerance to low P through molecular breeding is an effective alternative to increase crop productivity. In this study, a total of 111 diverse maize inbred lines were used to identify the favorable alleles and nucleotide diversity of candidate ZmNAC9, which plays an important role in response to low P and regulation in root architecture. A significant difference was found under low- and sufficient-P conditions for each of the 22 seedling traits, and a total of 41 polymorphic sites including 32 single nucleotide polymorphisms (SNPs) and 9 insertion and deletions (InDels) were detected in ZmNAC9 among 111 inbred lines. Among the 41 polymorphic studied sites, a total of 39 polymorphic sites were associated with 20 traits except for the dry weight of shoots and forks, of which six sites were highly significantly associated with ...
Research Interests:
Organisations cannot put their efforts equally into all the best practices that impact operational performance, due to their limited resources, their ineffective usage, government policies, and inadequate strategic planning. In this... more
Organisations cannot put their efforts equally into all the best practices that impact operational performance, due to their limited resources, their ineffective usage, government policies, and inadequate strategic planning. In this contribution, we aim to identify and prioritise the practices with the most impact on operational performance. Twelve practices that steer operational performance were identified through a literature survey. Second, the identified practices were prioritised and evaluated, based on improving operational performance by using a hybrid approach. The analytical hierarchy process (AHP) and the technique for order performance by similarity to ideal solution (TOPSIS) method were used such that AHP was applied to determine the relative weights of alternatives, and then the final ranking was obtained by conducting a TOPSIS analysis. Empirical data were collected from eight experts and 417 users at operational-level. The results suggest that lean management, total quality management, six sigma, and supply chain management practices rank 1st, 2nd, 3rd, and 4th respectively, signifying the practices with the most influence and making the greatest contribution. This strategic understanding will help researchers and practitioners to frame competitive strategies in order to pay more attention to those practices that have a greater influence on operational performance.
Research Interests:
For achieving world-class performance and competitiveness in today’s global highly complex environment and competition, there is an immense pressure on manufacturing organizations having limited resources to pursue operational excellence... more
For achieving world-class performance and competitiveness in today’s global highly complex environment and competition, there is an immense pressure on manufacturing organizations having limited resources to pursue operational excellence in terms of productivity and quality, reduce cost, and provide high-quality products in shorter lead times. Identification of representative practices affecting operational performance (OP) and understanding of mutual dependence among those practices will improve the performance of manufacturing organizations with available resources. A sample of 10 experts of academicians and senior company managers from different functional areas of large-scale textile, sugar, and cement industries were surveyed to identify critical practices influencing OP and then to develop the relationships among them. It also identifies those practices that support other practices (driving practices) and also those that are most influenced by other practices (dependent practi...
Research Interests:
Research Interests:
... Following is a short proof of the result given by Laradji and Thaheem in [5]. Theorem 0.4. Let R be a semiprime ring and f be a centralizing au-tomorphism of R. Then D(f) ⊆ Z(R). Proof. ... i i i i 246 Asif Ali and Muhammad Yasen By... more
... Following is a short proof of the result given by Laradji and Thaheem in [5]. Theorem 0.4. Let R be a semiprime ring and f be a centralizing au-tomorphism of R. Then D(f) ⊆ Z(R). Proof. ... i i i i 246 Asif Ali and Muhammad Yasen By Theorem 0.1, a(f(x) − x)[y, z]=[y, z](f(x) − x)a = 0. ...
Research Interests:
Research Interests:
Research Interests:
Native calf thymus DNA was modified with furocoumarins and reactive oxygen species (ROS). The modifications were probed by UV & Fluorescence spectroscopy, thermal denaturation and hydroxyapatite chromatography. In... more
Native calf thymus DNA was modified with furocoumarins and reactive oxygen species (ROS). The modifications were probed by UV & Fluorescence spectroscopy, thermal denaturation and hydroxyapatite chromatography. In CD spectroscopy changes in the ellipticity of the DNA molecule were observed as a result of modification. The binding specificity of naturally occurring anti-DNA antibodies with modified DNA molecules was assessed by ELISA and quantitative precipitin titration. The affinity of anti-DNA antibodies for modified conformers was found to be quite high.
Research Interests:
The DNA-psoralen crosslink induced precipitating antibodies in rabbits with a titer of 1:102,400 by direct binding ELISA. The antiserum showed considerable binding with Z-DNA and calf thymus DNA brominated under high salt concentration... more
The DNA-psoralen crosslink induced precipitating antibodies in rabbits with a titer of 1:102,400 by direct binding ELISA. The antiserum showed considerable binding with Z-DNA and calf thymus DNA brominated under high salt concentration which has been shown to attain Z-/analogous conformation. Inhibition experiments substantiated the results of direct binding assay. However, the affinity purified IgG showed high degree of specificity for the immunogen and did not recognize nDNA, Z-DNA and brominated DNA as inhibitor. Poly(dG.dC).poly(dG.dC)-psoralen photoadduct was found to be inhibitory. These results indicate that the antibodies are probably recognizing the unique conformation at the site of psoralen crosslinking. The DNA-psoralen crosslink showed significant binding with SLE sera known to have high levels of anti-native DNA antibodies. Affinity purified SLE-IgG in a competition assay pointed out the autoantibody recognition of altered conformation of DNA-psoralen crosslink.
Research Interests:
... 1 , Brian Harding 1 , M Andrew Nesbit 1 , Rebecca Fairclough 1 , Elena Grigorieva 2 , Asif Ali 1 , Tertius Hough 5 , William ... 3 Royal Liverpool University Hospital, Liverpool, United Kingdom; 4 Erasmus University, Rotterdam,... more
... 1 , Brian Harding 1 , M Andrew Nesbit 1 , Rebecca Fairclough 1 , Elena Grigorieva 2 , Asif Ali 1 , Tertius Hough 5 , William ... 3 Royal Liverpool University Hospital, Liverpool, United Kingdom; 4 Erasmus University, Rotterdam, Rotterdam, Netherlands; 5 Mary Lyon Centre, Medical ...
Research Interests:
Research Interests: Morphogenesis, Capillaries, Sheep, Female, Animals, and 7 moreMale, Skin, Embryonic Development, Foetus, Blood Vessels, Fetus, and Gestational Age
Rabbits immunized with polylysine-polyglutamate complex induced high titer antibodies. The immune IgG exhibited high degree of specificity towards the immunogen. In a competition assay, nDNA, heat denatured DNA and total buffalo thymus... more
Rabbits immunized with polylysine-polyglutamate complex induced high titer antibodies. The immune IgG exhibited high degree of specificity towards the immunogen. In a competition assay, nDNA, heat denatured DNA and total buffalo thymus RNA were inhibitory. An appreciable binding with polyglutamate, poly(rG).poly(dC) poly(dG).poly(dC), cardiolipin, poly(dA-dU). Poly(dA-dU) and Z- or Z-like conformations demonstrates the polyspecificity of induced antibodies. The immunological specificity of induced antibodies was comparable to autoantibodies derived from SLE. The results might be of some help in understanding the etiology of autoimmune process.
Research Interests:
Hyperglycemia is the defining feature of diabetes mellitus. The persistently high levels of reducing sugars like glucose and fructose cause glycation of various macromolecules in the body. Human serum albumin (HSA), the most abundant... more
Hyperglycemia is the defining feature of diabetes mellitus. The persistently high levels of reducing sugars like glucose and fructose cause glycation of various macromolecules in the body. Human serum albumin (HSA), the most abundant serum protein with a myriad of functions, is prone to glycation and consequent alteration in its structural and biological properties. This study aimed to assess the role of fructose-modified human serum albumin as a marker of diabetic pathophysiology. We carried out modification of HSA with fructose and the changes induced were studied by various physicochemical studies. Fructose modified-HSA showed hyperchromicity in UV spectrum and increased AGE-specific fluorescence as well as quenching of tryptophan fluorescence. In SDS-PAGE protein aggregation was seen. Amadori products were detected by NBT. The fructose modified HSA had higher content of carbonyls along with perturbations in secondary structure as revealed by CD and FT-IR. A greater hydrodynamic radius of fructose-modified HSA was evident by DLS measurement. The fructose-modified HSA induced high titre antibodies in experimental animals exhibiting high specificity towards the immunogen. © 2015 IUBMB Life, 2015 67(5):338-347, 2015.
Research Interests:
ABSTRACT INTRODUCTION Pancreatic ductal adenocarcinoma (PDAC) is common and aggressive with a 5-year survival of 2-3%. Initial assessment of patients involves imaging and diagnostic cytology at endoscopy. Pre-treatment diagnosis on... more
ABSTRACT INTRODUCTION Pancreatic ductal adenocarcinoma (PDAC) is common and aggressive with a 5-year survival of 2-3%. Initial assessment of patients involves imaging and diagnostic cytology at endoscopy. Pre-treatment diagnosis on cytology samples can be difficult to establish, and may be improved with diagnostic biomarkers. KOC (k homology domain protein) is highly expressed in PDAC but less in normal ducts. Therefore, KOC could help to increase the diagnostic accuracy of pancreatic ductal adenocarcinoma (PDAC) versus benign or inflammatory tissue. Our aim was to validate the expression of KOC in a local surgical cohort. MATERIAL AND METHODS Optimised antibodies for KOC were applied to 3 Tissue Microarray (TMA) slides containing a total of 256 cores (149 PDAC, 107 Normal Ducts) from 89 patients. Afterwards, we analysed the immunohistochemical expression of KOC with the intension of differentiating PDAC from normal pancreatic ducts. We selected cores for comparison purposes as negative, weak, moderate and strong for staining. The expression was visualised as a cytoplasmic stain of varying intensity and proportion in distiller 2.1. Results were quantitatively measured as a “weighted histoscore”, taking into account both the intensity of staining and the proportion of cells being positive [Histoscore= (negative=0×%cells + weak=1×%cells + moderate=2×%cells + strong=3×%cells)]. RESULTS Immunohistochemical analysis of KOC expression showed heterogeneity of staining in PDAC but not in normal ductal tissues. Overall average percentage of KOC expressing cells across all cores in 3 TMAs for PDAC samples was 77.9% (range, 0%-100%), however in normal pancreatic ducts it was 0.32% (range, 0%-10%) [p <.0001, Independent sample t test]. Similarly, the average histoscore for PDAC samples was 153 (range, 0-300), while for normal ducts it was 0.52 (range, 0-18) [p <.0001, Independent sample t test]. Finally, with a cut-off of 12.5% positivity of cells and at least weak staining, a sensitivity of 83.9% and specificity of 100% was achieved. CONCLUSION The results of this study with 100% specificity and almost 84% sensitivity demonstrate that KOC expression is essentially restricted to PDAC in tissue samples. Thus it has the potential to increase the diagnostic accuracy of cytological samples of PDAC, but further studies on cytologic samples of PDAC and normal ducts are required. J Pathol Inform. 2011; 2: 43c. > Sub-article 2
The effect of gum Arabic oral treatment on the iron and protein status in chronic renal failure patients under regular hemodialysis in Central Sudan L'effet du traitement oral par de la gomme arabe sur le statut martial et de protéinémie chez les patients en insuffisance rénale chronique sous hém...more
Research Interests:
Research Interests:
Glyco-oxidation of proteins has implications in the progression of diabetes type 2. Human serum albumin is prone to glyco-oxidative attack by sugars and methylglyoxal being a strong glycating agent may have severe impact on its structure... more
Glyco-oxidation of proteins has implications in the progression of diabetes type 2. Human serum albumin is prone to glyco-oxidative attack by sugars and methylglyoxal being a strong glycating agent may have severe impact on its structure and consequent role in diabetes. This study has probed the methylglyoxal mediated modifications of HSA, the alterations in its immunological characteristics and possible role in autoantibody induction. We observed an exposure of chromophoric groups, loss in the fluorescence intensity, generation of AGEs, formation of cross-linked products, decrease in α-helical content, increase in hydrophobic clusters, FTIR band shift, attachment of methylglyoxal to HSA and the formation of N(ε)-(carboxyethyl) lysine in the modified HSA, when compared to the native albumin. MG-HSA was found to be highly immunogenic with additional immunogenicity invoking a highly specific immune response than its native counterpart. The binding characteristics of circulating autoan...
Research Interests:
Non-enzymatic lipid peroxidation of cellular membranes occurs during periods of sustained oxidative stress. 4-hydroxynonenal (HNE), the most reactive lipid peroxidation product, is capable of modifying and/or cross-linking proteins... more
Non-enzymatic lipid peroxidation of cellular membranes occurs during periods of sustained oxidative stress. 4-hydroxynonenal (HNE), the most reactive lipid peroxidation product, is capable of modifying and/or cross-linking proteins leading to impaired physiological functions. The formation of protein adducts produce structural modifications which generate neo-antigens and induce auto-antibodies. Enhanced oxidative stress and accumulation of HNE-modified proteins are associated with systemic lupus erythematosus (SLE) and other autoimmune diseases. This study has probed the role of lipid peroxidation derived aldehydes in SLE. We report the structural perturbations in human serum albumin (HSA) upon modification with HNE and the consequential enhanced immunogenicity. The induced antibodies were found to be highly specific for the immunogen and exhibited cross-reactivity with HNE-modified epitopes on proteins, amino acids and nucleic acid. The experimentally induced anti-HNE-HSA antibodies appreciably recognized HNE modified epitopes on the HSA obtained from SLE patients. These antibodies, therefore, from a good immunochemical probe to detect such damages in lupus patients. Possible role of anti-HNE-HSA antibodies as a marker for detection/progression of SLE has been discussed.
Research Interests:
Two experiments were conducted to investigate whether mental practice can serve as an effective intervention strategy for decreasing interference effects of distracting noise at the time of executing open (badminton service return) and... more
Two experiments were conducted to investigate whether mental practice can serve as an effective intervention strategy for decreasing interference effects of distracting noise at the time of executing open (badminton service return) and closed (badminton serve) skills. In Experiment 1, 44 male students participated and in Experiment 2, 36 students participated. In both experiments, students were randomly assigned to one of three groups: (a) mental practice, (b) mental practice plus noise distraction (MPD), and (c) control. All participants performed 40 trials in the acquisition phase and 20 trials in the retention phase. Absolute error and adjusted variable error were recorded to measure performance. Experiment 1 showed that for a closed skill, the MPD group served with greater accuracy than did the control group in both acquisition and retention phases. Experiment 2 showed that for the open skill, the MP group performed with less error than did the control group, but only in the acquisition trials. Results indicate that mental practice may function to block out noise disturbances and that mental practice may work differently with different skill sets.
Research Interests:
Research Interests:
ABSTRACT
In the recent scenario, Polymer concrete has been developed as an innovative architectural material due to its high performance as compare to conventional materials. Polymer concrete has many advantages over conventional Portland Cement... more
In the recent scenario, Polymer concrete has been developed as an innovative architectural material due to its high performance as compare to conventional materials. Polymer concrete has many advantages over conventional Portland Cement Concrete, such as high mechanical properties, rapid hardening, durability, and resistant to chemical and biological effects. Sufficiently large amount of research work has been carried out during the last few years and reported that Polymer concrete has ability of application in the advancement of construction industries. In this paper, authors reviewed the status of Polymer concrete and its application as sustainable building material.
Research Interests:
The present study describes the anti-leukemic potential of a novel stereo bioactive secondary metabolite, (R)-5-hydroxy-2-methylchroman-4-one (HMC) isolated from a novel endophytic fungus source (Cryptosporiopsis sp. H2-1, NFCCI-2856),... more
The present study describes the anti-leukemic potential of a novel stereo bioactive secondary metabolite, (R)-5-hydroxy-2-methylchroman-4-one (HMC) isolated from a novel endophytic fungus source (Cryptosporiopsis sp. H2-1, NFCCI-2856), associated with Clidemia hirta. HMC inhibited cell proliferation of different cancer cell lines with IC50 values in the range of 8-55µg/ml. The cytotoxicity window of HMC was 6-12 times lower in normal cells as compared to susceptible leukemic HL-60, MOLT-4 and K-562 cells. It persuades apoptosis through both intrinsic and extrinsic pathways in above leukemic cell lines, which was evident through Hoechst staining, Annexin-V binding, cell cycle analysis, loss of mitochondrial membrane potential (Δψm), release of cytochrome c, Bax, Bid, over-expression of apical death receptors, activation of caspase-3,-8,-9 and PARP (poly ADP ribose polymerase) cleavage. HMC induced caspase dependent apoptosis and robustly attenuate transcription factor, p-STAT-3 in myeloid and lymphoid leukemia cells. The mechanism of HMC arbitrated inhibition of p-STAT-3 was due to the activation of ubiquitin dependent degradation of p-STAT-3. Therefore, our study not only describes the anti-leukemic potential of HMC but also provides insights into how endophytes can be useful in discovery and development of novel anticancer therapeutics.
Research Interests:
This is an investigation in the tradition of Fujita et al (IJCAI 1993), Zhang et al (JSC 1996), Dubois and Dequen (CP 2001) in which CP or SAT techniques are used to answer existence questions concerning small algebras. In this paper, we... more
This is an investigation in the tradition of Fujita et al (IJCAI 1993), Zhang et al (JSC 1996), Dubois and Dequen (CP 2001) in which CP or SAT techniques are used to answer existence questions concerning small algebras. In this paper, we open the attack on IP loops, an interesting and under- investigated variety intermediate between loops and groups.
Research Interests:
A spectrophotometric method was developed based on the microwave assisted synthesis of Maillard product. Various conditions of the reaction were optimized by varying the relative concentration of the reagents, operating temperature and... more
A spectrophotometric method was developed based on the microwave assisted synthesis of Maillard product. Various conditions of the reaction were optimized by varying the relative concentration of the reagents, operating temperature and volume of solutions used in the reaction in the microwave synthesizer. The absorbance of the microwave synthesized Maillard product was measured in the range of 360-740nm using UV-Visible spectrophotometer. Based on the maximum absorbance, 370nm was selected as the optimum wave length for further studies. The LOD and LOQ of glucose was found 3.08μgmL(-1) and 9.33μgmL(-1) with standard deviation of ±0.05. The developed method was also applicable to urine sample.
Research Interests:
Research Interests:
Research Interests:
ABSTRACT This paper presents the summary of a recently completed dissertation by the author keeping in view the objectives viz. 1) to study and identify the essential elements of the mosque, their meanings and their functions, 2) to study... more
ABSTRACT This paper presents the summary of a recently completed dissertation by the author keeping in view the objectives viz. 1) to study and identify the essential elements of the mosque, their meanings and their functions, 2) to study the evolution of the mosque architecture in Delhi from early Islamic period to present time and 3) to identify and establish the continuity and the change in the morphology of the mosque in Delhi and the factors which influenced its development through time. To answer the research question and to accomplish the objectives mentioned above, following methodologies were adopted. In order to view the continuity and changes in the mosque architecture in Delhi, it seemed essential to study their historical enquiry. It was not only the survey of the historical mosque but the approach was to understand the future of mosque architecture through their past. This enquiry allowed us to observe the evolution of the mosque architecture and the study of its diffe...
Research Interests:
Mosque is a social and religious centre for the Muslims and it is a place of assembly for the Muslims five times a day. Being an essential structure of Muslim societies and being a place of worship, mosques have extraordinarily been... more
Mosque is a social and religious centre for the Muslims and it is a place of assembly for the Muslims five times a day. Being an essential structure of Muslim societies and being a place of worship, mosques have extraordinarily been outstanding examples of architectural beauty throughout. The first mosque built by prophet was austere, strictly functional and sober, but with the spread of Islam, mosque architecture with regional accents in different countries reflected diversity in its design as well as style. In India the early mosques were built in the south, on Malabar Coast and in the west, the Indus region. However the prolific development of mosque architecture was started only after the arrival of Muslims as rulers in North India. Delhi, being the first confronter and epicenter of Muslims rule throughout ages, reflects the continuity in the development of mosque architecture in North India. This paper reveals the architectural development of mosques in Delhi which consequently...
-Self-controlled feedback on a variety of tasks are well established as effective means of facilitating motor skill learning. This study assessed the effects of self-controlled feedback on the performance of a serial motor skill. The task... more
-Self-controlled feedback on a variety of tasks are well established as effective means of facilitating motor skill learning. This study assessed the effects of self-controlled feedback on the performance of a serial motor skill. The task was to learn the sequence of 18 movements that make up the Taekwondo Poomsae Taegeuk first, which is the first beginner's practice form learned in this martial art. Twenty-four novice female participants (M age = 27.2 yr., SD = 1.8) were divided into two groups. All participants performed 16 trials in 4 blocks of the acquisition phase and 20 hr. later, 8 trials in 2 blocks of the retention phase. The self-controlled feedback group had significantly higher performance compared to the yoked-feedback group with regard to acquisition and retention. The results of this study may contribute to the literature regarding feedback by extending the usefulness of self-controlled feedback for learning a serial skill.
Research Interests:
DESCRIPTION High temperature corrosion on SS in different environments. Graduate research work. Working Paper.
Research Interests:
Hyperglycemia is the defining feature of diabetes mellitus. The persistently high levels of reducing sugars like glucose and fructose cause glycation of various macromolecules in the body. Human serum albumin (HSA), the most abundant... more
Hyperglycemia is the defining feature of diabetes mellitus. The persistently high levels of reducing sugars like glucose and fructose cause glycation of various macromolecules in the body. Human serum albumin (HSA), the most abundant serum protein with a myriad of functions, is prone to glycation and consequent alteration in its structural and biological properties. This study aimed to assess the role of fructose-modified human serum albumin as a marker of diabetic pathophysiology. We carried out modification of HSA with fructose and the changes induced were studied by various physicochemical studies. Fructose modified-HSA showed hyperchromicity in UV spectrum and increased AGE-specific fluorescence as well as quenching of tryptophan fluorescence. In SDS-PAGE protein aggregation was seen. Amadori products were detected by NBT. The fructose modified HSA had higher content of carbonyls along with perturbations in secondary structure as revealed by CD and FT-IR. A greater hydrodynamic radius of fructose-modified HSA was evident by DLS measurement. The fructose-modified HSA induced high titre antibodies in experimental animals exhibiting high specificity towards the immunogen. © 2015 IUBMB Life, 2015 67(5):338-347, 2015.
Research Interests:
Research Interests:
ABSTRACT An analysis is performed for flow and heat transfer of a non-Newtonian fluid known as Casson fluid over a permeable stretching surface through a porous medium. Lie Group analysis is used to reduce the governing partial... more
ABSTRACT An analysis is performed for flow and heat transfer of a non-Newtonian fluid known as Casson fluid over a permeable stretching surface through a porous medium. Lie Group analysis is used to reduce the governing partial differential equations to non-linear ordinary differential equations. These equations are then solved and solutions are obtained in terms of Kummer’s function. A comprehensive study of the problem is made for various parameters.
To evaluate the blood ordering practice and blood transfusion for Caesarean sections at our institution and to compare the estimated blood loss between anaesthetists and obstetricians. A review of 126 patients undergoing both elective and... more
To evaluate the blood ordering practice and blood transfusion for Caesarean sections at our institution and to compare the estimated blood loss between anaesthetists and obstetricians. A review of 126 patients undergoing both elective and emergency Caesarean section was undertaken in 2002. Information collected included the number of blood units cross-matched preoperatively, type of surgery (emergency or elective), type of anaesthesia, parity of the patient, estimated blood loss by both anaesthetists and obstetricians, intraoperative and postoperative transfusion within 48 hours and pre and post operative haemoglobin (Hb) and haemocrit (Hct). A total of 215 units were cross-matched for 126 patients undergoing Caesarean section delivery. A small amount (9.5%) were transfused intraoperatively and 5.5% postoperatively. The average blood loss estimated by anaesthetists was 498 +/- 176 ml and that by obstetricians was 592 +/- 222 ml. The calculated blood loss based on patients blood volu...
Research Interests:
Research Interests:
In prospective study, the various reasons for conversion in laparoscopic cholecystectomy were shown and recommended various measures to decrease the incidence of conversion and associated complications with this procedure. Fifty cases of... more
In prospective study, the various reasons for conversion in laparoscopic cholecystectomy were shown and recommended various measures to decrease the incidence of conversion and associated complications with this procedure. Fifty cases of conversion in laparoscopic cholecystectomy were studied in Dhaka Medical College Hospital & Bangabandhu Sheikh Mujib Medical University from July 2002 to July 2004. The commonest cause of conversion was dense pericholecystic adhesion or unclear anatomy (24%). Next common cause was accidental injury to surrounding structures (18%) and uncontrolled bleeding (14%) and thick fibrosed gall bladder (14%). Other causes were gall bladder wall perforation (6%), carcinoma gall bladder (6%) and choledocholithiasis (6%), anatomic variation (4%), equipment failure (4%), cholecystoduodenal fistula (2%) and choledochal cyst (2%). Proper case selection, good laparoscopic skill and adequate experience of the surgeon are the prerequisites for safe laparoscopic cholec...