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The admission of a patient in intensive care justified by the severity of the disease, is a stressful situation for his heirs. A fair and understandable information is a major component of the process quality of care. Evaluate the... more
The admission of a patient in intensive care justified by the severity of the disease, is a stressful situation for his heirs. A fair and understandable information is a major component of the process quality of care. Evaluate the practice of informing families of patients and their satisfaction in intensive care unit. We conducted a prospective study of 90 families of patients. The demographics of family representatives, and satisfaction data were collected. The majority of parents were aged between 20-40. The sex ratio was 2.9 for men. The siblings had accounted for 23 parents whether 25,6%. In 46 cases whether 51%, the relatives of families were satisfied with information received. 57.8% did not have good information on the risks of treatment complications. The lack of explanation about the evolution of the disease remained a major concern for 36 families. 69 of parents whether 76.7% felt that the frequency of visits was satisfactory. In our series no contradiction has been recor...
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Describe the severity of bone lesion and evaluate the results of the treatment of osteomyelitis in patients with sickle cell disease. It was about a prospective study done from December 2005 to November 2006 in patients with confirmed... more
Describe the severity of bone lesion and evaluate the results of the treatment of osteomyelitis in patients with sickle cell disease. It was about a prospective study done from December 2005 to November 2006 in patients with confirmed sickle cell admitted for osteomyelitis. We gather together 62 cases of osteomyelitis in sickle cell disease among 120 cases, which was about 51.7%. The mean age has been 17 years. The diagnosis was made on biology and x rays. 46.78% of our patients were sickle cell homozygote. Bone pain was the 1st reason of consultation with 53.2% of cases. Staphylococcus aureus and salmonella were the most frequent germs, with 43.55% each. Complications were noted in 32.26% because of diagnosis delay (P 0.05). Delay in the management or incorrect treatment can result in a severe and definitive sequel for the functional future of those patients.
Research Interests: Sickle Cell Anemia, Adolescent, Mali, Prospective studies, Humans, and 6 moreChild, Female, Male, Young Adult, Osteomyelitis, and Adult
The purpose of our entomological survey was to estimate mosquito biodiversity, infectivity rates and insecticide resistance levels in Anopheles species in four study sites in a mining area with high malaria transmission in southeastern... more
The purpose of our entomological survey was to estimate mosquito biodiversity, infectivity rates and insecticide resistance levels in Anopheles species in four study sites in a mining area with high malaria transmission in southeastern Guinea. Anopheles gambiae s.l. (77%) was the most common Anopheles collected followed by An. funestus (20%). The specimens of the An. gambiae complex were predominantly An. gambiae S form (97.6%) with 1.4% of An. gambiae M form found in Kérouané only, and 1% of An. arabiensis which was present in all four study sites. Anopheles gambiae S form and An. funestus were found to be infected with Plasmodium falciparum, with infectivity rates of 4.1% and 4.4% and inoculation rates of 0.60 and 0.19 infected bite/person/night, respectively. In addition, a high level (79%) of the knockdown resistance (kdr) L1014F mutation was reported in the populations of An. gambiae S form. The high malaria transmission that occurs in the prospected area of Guinea requires a l...
Research Interests: Microbiology, Medical Microbiology, Malaria, Gene Silencing, Insecticides, and 16 moreInsecticide Resistance, Guinea, Humans, Mutation, Anopheles, Female, Animals, Male, Polymerase Chain Reaction, Culex, Anopheles gambiae, Vector control, Genotype, Public health systems and services research, Plasmodium falciparum, and Insect Vectors
Twenty-four percent of the Gabonese population has sickle cell trait, and 1-3% has sickle cell disease. Patients' management must follow well-defined protocols that take into account the debilitating effect of severe pain episodes. To... more
Twenty-four percent of the Gabonese population has sickle cell trait, and 1-3% has sickle cell disease. Patients' management must follow well-defined protocols that take into account the debilitating effect of severe pain episodes. To evaluate the three-step analgesic ladder for control of pain for sickle cell disease pain crises. This is a prospective and descriptive study based on surveys filled between February 2000 and March 2001. Surveys were restricted to sickle cell disease patients having developed pain crises before and during their stay at the hospital. The assessment of the pain was based on the DEGR and EVA scales. The treatment followed the World Health Organisation's analgesic ladder. The criteria used for estimate pain severity and sedation duration were measured before, 2 and 24 h after treatment administration began (H0, H2 and H24) to evaluate its effectiveness. Sixty children were included. All the social layers of the population were represented. The scho...
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ABSTRACT Objectives To assess the prevalence of exercise-induced bronchospasm in athletes living in humid tropical environment. Methods This prospective investigation, carried out in Abidjan in september 2001, have concerned 108 athletes... more
ABSTRACT Objectives To assess the prevalence of exercise-induced bronchospasm in athletes living in humid tropical environment. Methods This prospective investigation, carried out in Abidjan in september 2001, have concerned 108 athletes of competition. After a questionnaire relative to asthma and atopie, each athlete underwent an exercise challenge. The temperature and the humidity were recorded. Criteria for exercise-induced bronchospasm was a decrease of the forced expiratory volume in one second greater or equal to 10% and/or a decrease of the peak expiratory flow greater or equal to 15%. Results The averages of ambient temperature and relative humidity were respectively 30.1 ± 1.6 °C et 82.6 ± 6.3%. According to the questionnaire, 13% of athletes were asthmatics or had symptoms of asthma and 36.1% had symptoms of atopie. According to the fall of the forced expiratory volume in 1 second, the fall of the peak expiratory flow and the fall of forced expiratory volume in 1 second and/or peak expiratory flow, the prevalences of exercise-induced bronchospasm were respectively 22.2%, 35.2% and 42.6%. These falls occured especially between the 1st and the 15th minute after exercise. Conclusion The results of this study were not in favour of the hypothesis according to which inhalation of warm and wet air protected from bronchospasm.
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According to WHO estimates, every year 4 millions of newborns die during the first four weeks of life. In Mali, neonatal mortality rate is 57.1‰ (DHS 2001). The aim of this work was to determine the importance as well as factors of... more
According to WHO estimates, every year 4 millions of newborns die during the first four weeks of life. In Mali, neonatal mortality rate is 57.1‰ (DHS 2001). The aim of this work was to determine the importance as well as factors of neonatal mortality risk in rural area. The cross-sectional survey took place on September 1st to October 4th, 2004 in Kolokani located in the region of Koulikoro in Mali. The authors led an exhaustive investigation of women having delivered one year before the investigation. The rate of birth waited to Kolokani being 5%, they foresaw to interrogate 10,015 womens. The living births represented 97.1% (8242/8486) and stillborns 2.9% (244/8486). Neonatal mortality rate was 24‰ (199/8242) of which 17‰ (140/8486) for early neonatal death and 7‰ (59/8242) for late neonatal mortality. Perinatal mortality rate was 45‰ (384/8242). According to the logistic regression modal, twin pregnancy, mictional itching, low birth weight, feet edema and non cephalic presentation were the risks factors significantly associated with neonatal mortality. The neonatal mortality rate of 24‰ in Kolokani was lower than those reported by DHS 2001 (57.1‰). Factors identified for neonatal mortality were associated with the mother health, the conditions of pregnancy and the childbirth. The authors recommend setting up identification and monitoring system for pregnant women, to train the health staff and to organize the frame of reference between villages and health centers.
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Burkitt's lymphoma was first described in Africa where it remains one of the most common malignant tumors in children. To our knowledge there have been no large series describing Burkitt's lymphoma involving the maxillofacial area... more
Burkitt's lymphoma was first described in Africa where it remains one of the most common malignant tumors in children. To our knowledge there have been no large series describing Burkitt's lymphoma involving the maxillofacial area or any other location in Malian children. The purpose of this retrospective single-center study was to describe clinical, laboratory, and therapeutic findings in children treated for maxillofacial Burkitt's lymphoma in the Oncology Unit of the Gabriel Touré Pediatric Hospital in Bamako, Mali from January to December 2006. A total of 38 cases of Burkitt's lymphoma were diagnosed during the study period. This series includes 24 children (63.2%) under the age of 15 years in whom diagnosis of previously untreated maxillofacial Burkitt's lymphoma was confirmed by cytology. All patients were treated using the GFA 2005 protocol for Burkitt's lymphoma. There were 17 boys and 7 girls (sex ratio of 2.4). In all cases the disease was advanced,...
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Become almost non-existent in the developed countries, the hospital-borne tetanus always stays of current events in our country in spite of the forensic problem which it puts. The objectives of this study were to determine prevalence of... more
Become almost non-existent in the developed countries, the hospital-borne tetanus always stays of current events in our country in spite of the forensic problem which it puts. The objectives of this study were to determine prevalence of this affection, to describe its clinical picture and to determine its lethality. It is about a retrospective study of a duration of 11 years realized in the service of the infectious diseases of Conakry. Among 8649 hospitalizations from 2001 till 2012 we brought together 239 cases of tetanus (2.7%) among which 60 hospital-borne tetanus (0.7%). Men represented 73% of these cases, with a sex-ratio M/F of 2.7. The age bracket of 20-40 years was the most affected with 32 cases (53.3%). A single patient had begun his vaccinal calendar which had remained incomplete. Both national hospitals of the CHU of Conakry and private hospitals were the biggest suppliers of this hospital-borne tetanus with respectively 22 and 27 cases (36.6 and 45%). Tetanus related t...
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Establish the frequency of osteoarthritis in our service an establish an adequate therapeutic protocol. It is about a retro and prospective study realised from January 2001 till January 2004 on all the 0 to 15 years old children treated... more
Establish the frequency of osteoarthritis in our service an establish an adequate therapeutic protocol. It is about a retro and prospective study realised from January 2001 till January 2004 on all the 0 to 15 years old children treated and followed in the service for osteoarthritis. Ten patients having no complete file or having disappeared during the study were excluded. 41 cases of osteoarthritis brought together in 26 boys and 15 girls. It occupied 0.8% of the hospitalization and 1.14% of the surgical activities. The average age of our patients was of 4.58 years+/-4.41 with extremes going from 0 to 15 years old. The noted facilitating factor was sickle cell disease (70.7%). The hip was the most affected articulation (48.8%). The staphylococcus was the most met germ (48.8%). A meticulous examination of a child presenting an articular pain and its management within a better time are necessary to avoid the frequent invalidating sequel in our country.
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This work presents the results of the behavioural and serologic survey on HIV/AIDS conducted from December 2007 to December 2008 among the group of STD (sexually transmitted disease) patients, supposed to be at HIV infection risk. In... more
This work presents the results of the behavioural and serologic survey on HIV/AIDS conducted from December 2007 to December 2008 among the group of STD (sexually transmitted disease) patients, supposed to be at HIV infection risk. In Mauritania, the last survey of HIV seroprevalence among the STD patients goes up to the year 1995 (the prevalence was estimated then to be 0.9%). The goal was to determine the seroprevalence of HIV and syphilis and to gather information on the knowledge, the sexual behaviours on a risk concerning the HIV/AIDS, and the sexually transmitted disease among these patients. The census has been made on over 224 STD patients during the period of the study, without predominance of sex and with a majority of young adults. The prevalence for HIV is 9% and for the syphilis it is 10%. Actually, the condom is widely underused by this group, even in occasional intercourse. The STD patients are a group of risk towards HIV, because of their risk behaviours and low level of knowledge.
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Introduction Approximately 20 000 new cases of Hodgkin lymphoma are diagnosed each year in North America and Europe. However in Africa, the incidence of this condition is almost unknown. While publications from western countries and the... more
Introduction Approximately 20 000 new cases of Hodgkin lymphoma are diagnosed each year in North America and Europe. However in Africa, the incidence of this condition is almost unknown. While publications from western countries and the rest of world are numerous in the literature, few data from Africa about this malignancy are available. The aim of this retro and prospective, unicentric
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Research Interests: Microbiology, Immunology, Medical Microbiology, Malaria, Adolescent, and 23 moreMaternal Health, Mali, Humans, Child, Microbes, Yellow fever, Female, Male, Regression Analysis, Infant, Anemia, Risk factors, Logistic Regression Analysis, Analysis of Variance, Breast feeding, Plasmodium falciparum, Educational Status, Disease Progression, Risk Factors, Case Control Study, Cerebral Malaria, Confidence Interval, and Case Control Studies
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RESUME : Il s'agit d'une étude rétrospective de type descriptif sur une période de 4 ans, allant du 01Avril 1999 au 31 Mars 2003. L'objectif était de déterminer les facteurs liés à la morbidité et à la mortalité des affections rénales... more
RESUME : Il s'agit d'une étude rétrospective de type descriptif sur une période de 4 ans, allant du 01Avril 1999 au 31 Mars 2003. L'objectif était de déterminer les facteurs liés à la morbidité et à la mortalité des affections rénales dans le service de Néphrologie du CHU de Conakry. L'étude a porté sur 606 patients hospitalisés dont 21 dialysés. Les paramètres de l'étude étaient l'âge, le sexe, la fréquence des affections rénales, la mortalité, les pathologies associées, le délai de consultation, la prise en charge, le traitement reçu avant l'hospitalisation, la durée d'hospitalisation, les horaires de décès et certains facteurs de risque cardio-vasculaires (tabac, alcool). Les malades ayant répondu aux critères de sélection étaient 365 hommes (60,23%) et 241 femmes (39,77%) avec un sex-ratio de 1,51. La moyenne d'âge était de 44 ± 17 ans avec des extrêmes de 15 et 95 ans ; 16,34% des patients étaient âgés de moins de 25 ans et 14,03% avaient plus de 65 ans. Selon la prise en charge, 462 (76,24%) étaient à la charge de leur entourage, seuls 144 (23,76%) pouvaient se prendre en charge pour les soins. Selon le traitement reçu avant l'hospitalisation, 357 avaient consommé des décoctions de feuilles et de racines, 86 avaient consulté un centre de santé. La durée moyenne d'hospitalisation a été de 13 ± 9 jours avec des extrêmes de 1 et 80 jours. Le tabagisme avait été observé chez 183 malades dont 181 hommes et l'alcoolisme chez 134 malades dont 122 hommes. Les affections rénales étaient l'insuffisance rénale chronique (51%), l'hypertension artérielle (30,36%), les glomérulonéphrites chroniques (8,09%), l'insuffisance rénale aiguë (7,59%), les infections urinaires (1,65%) les glomérulonéphrites aiguës (0,99%) et le cancer du rein (0,33%). Parmi eux, 130 décès avaient été observés soit 21,45%. Selon le délai écoulé avant la consultation, 24 décès étaient survenus 2 semaines après le premier symptôme et 106 après plus d'un mois. Suivant les horaires, 33 décès (25,38%) étaient survenus entre 8h et 16h et 63 décès (48,47%) entre 16h et 8h ; dans 34 cas, l'heure n'était pas précisée. La mortalité était due à l'insuffisance rénale chronique dans 97 cas, soit 74,61%, à l'hypertension artérielle dans 19 cas, soit 14,62% et aux autres affections dans 14 cas, soit 0,77%. Les infections, le diabète, l'hypertension artérielle et la drépanocytose étaient les facteurs de risque rénal. Les facteurs de morbidité et de mortalité étaient nombreux et variés à savoir : le retard à la consultation, le traitement traditionnel, le faible revenu des malades, l'absence de couverture sanitaire, le manque de prise en charge correct au cours des gardes, le manque d'équipement adéquat et l'absence d'éducation sanitaire populaire. Summary: It is a retrospective study of descriptive type on a 4 years period, from April 1, 1999 to march 31, 2003. The aim was to determine factors bound to morbidity and mortality of renal affections in the Conakry University Hospital Canter Nephrology Unit. The study was based on 606 hospitalized patients of whom 21 dialysed. The study's references were age, sex, renal affections frequence, mortality, associated pathologies, hospitalization period, death hours and other factors of cardio-vascular risks (tobacco, alcohol). Patients having answered to the selection criteria were 365 men (60, 23%) and 241 women (39,77%) with a sex ratio of 1,51. The average age was 44 ± 17 years old with extremes of 15 and 95 years old; 16,34% of the patients were aged less than 25 years and 14,03% were more than 65 years old. According to the charge taking, 462 (76, 24%) were at their neighbors'charge, only 144 (23,76%) could take themselves in charge for their medical care. According to the received treatement before hospitalization, 357 had consumed decoctions of leaves and roots, 86 consulted a health center. The average period of hospitalization was 13 ± 9 days with extremes of 1 and 80 days. Nicotine addiction was observed with 183 patients of whom 181 were men and alcoholism with 134 patients of whom 122 were men. Renal affections were chronic renal failure (51%), arterial hypertension (30, 36%), chronic kidney disease (8, 09%), intense renal failure (7,59%), urinary infections (1,65%), intense kidney disease (0,99%) and kidney cancer (0,33%). Among them, 130 deaths were observed (21, 45%). According to the period going on before the medical check up, 24 death occured 2 weeks after the first symptom, and 106 after more than a mouth. Considering the hours, 33 death (25, 38%) occured between 8 a.m. and 4 p.m. and 63 deaths (48, 47%) between 4 p.m. and 8 a.m.; in 34 cases, the hour was not specified. Mortality was due to chronic renal failure in 97 cases (74,61%), to arterial hypertension in 19 cases (14,62%) and to other affections in 14 cases (0,77%). Infections, diabetis, arterial hypertension and sicklemia were renal risk factors. Morbidity and mortality factors were numerous and varied: medical check up delay, traditional cure, patients 'weak turnover, lack of medical care, lack of required equipment and the absence of popular health education.