ASAIO journal (American Society for Artificial Internal Organs : 1992)
Cardiopulmonary bypass causes a systemic inflammatory reaction. Activation of leukocytes is an im... more Cardiopulmonary bypass causes a systemic inflammatory reaction. Activation of leukocytes is an important part of this process, and is known to directly contribute to the development of postoperative coagulopathy, and thus hemorrhage. The removal of leukocytes from the cardiopulmonary bypass circulation, using specialized filters, has been proposed as one method for attenuating this inflammatory response. However, there is no consensus on its effectiveness. We used meta-analytical techniques to systematically assess the literature reporting on the potential effect of systemic leukofiltration on perioperative hemorrhage. Random effects modeling was used to calculate overall estimate, and heterogeneity was assessed. Systemic leukofiltration made no significant impact on chest tube drainage in the first 24 hours (weighted mean difference [WMD], x23.9 ml; 95% confidence interval [CI], x95.48-47.61; p = 0.51) or on the total packed red cell transfusion requirements of each patient (WMD, 7...
... Alison Walker, BSc(Hons), MbChB, MRCPCH, Mark Davidson, MBChB, Mrcpch, BSc(Med Sci), Elizabet... more ... Alison Walker, BSc(Hons), MbChB, MRCPCH, Mark Davidson, MBChB, Mrcpch, BSc(Med Sci), Elizabeth Chalmers, MChB, MD, MRCP, FRCPath, Royal ... Accessed March 18, 2010 3. Spenceley N, Krahn G, Skippen PW, et al: Evaluation of a pediatric central venous oxim-etry ...
... Trainees and junior faculty will also benefit from a number of “how to” chapters focused on d... more ... Trainees and junior faculty will also benefit from a number of “how to” chapters focused on data presentation, critical reading, writing papers, and submitting grants. ... Timothy M. Pawlik, MD, MPH,. Steven Leach MD. Johns Hopkins University. ...
... Research: Concepts and Methodology Mohammed Shamim Rahman, Sana Usman, Oliver Warren, and Tha... more ... Research: Concepts and Methodology Mohammed Shamim Rahman, Sana Usman, Oliver Warren, and Thanos Athanasiou 36 ... Disproportionate sampling does not follow equal weighting and allows over sam-pling of a small but important stratum. ...
ASAIO journal (American Society for Artificial Internal Organs : 1992)
Cardiopulmonary bypass causes a systemic inflammatory reaction. Activation of leukocytes is an im... more Cardiopulmonary bypass causes a systemic inflammatory reaction. Activation of leukocytes is an important part of this process, and is known to directly contribute to the development of postoperative coagulopathy, and thus hemorrhage. The removal of leukocytes from the cardiopulmonary bypass circulation, using specialized filters, has been proposed as one method for attenuating this inflammatory response. However, there is no consensus on its effectiveness. We used meta-analytical techniques to systematically assess the literature reporting on the potential effect of systemic leukofiltration on perioperative hemorrhage. Random effects modeling was used to calculate overall estimate, and heterogeneity was assessed. Systemic leukofiltration made no significant impact on chest tube drainage in the first 24 hours (weighted mean difference [WMD], x23.9 ml; 95% confidence interval [CI], x95.48-47.61; p = 0.51) or on the total packed red cell transfusion requirements of each patient (WMD, 7...
... Alison Walker, BSc(Hons), MbChB, MRCPCH, Mark Davidson, MBChB, Mrcpch, BSc(Med Sci), Elizabet... more ... Alison Walker, BSc(Hons), MbChB, MRCPCH, Mark Davidson, MBChB, Mrcpch, BSc(Med Sci), Elizabeth Chalmers, MChB, MD, MRCP, FRCPath, Royal ... Accessed March 18, 2010 3. Spenceley N, Krahn G, Skippen PW, et al: Evaluation of a pediatric central venous oxim-etry ...
... Trainees and junior faculty will also benefit from a number of “how to” chapters focused on d... more ... Trainees and junior faculty will also benefit from a number of “how to” chapters focused on data presentation, critical reading, writing papers, and submitting grants. ... Timothy M. Pawlik, MD, MPH,. Steven Leach MD. Johns Hopkins University. ...
... Research: Concepts and Methodology Mohammed Shamim Rahman, Sana Usman, Oliver Warren, and Tha... more ... Research: Concepts and Methodology Mohammed Shamim Rahman, Sana Usman, Oliver Warren, and Thanos Athanasiou 36 ... Disproportionate sampling does not follow equal weighting and allows over sam-pling of a small but important stratum. ...
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