Roger Binny

The importance of antioxidant constituents in maintenance of health attracted research in plant based antioxidants. Presence of amino acid argenine and secondary metabolites like flavonoids and phenolic compounds and antibacterial activity leads for the evaluation of antioxidant activity of Sebastiania chamaelea leaf aqueous extracts. In-vitro free radical scavenging LC 50 at 100-90 µg/ml, and r educing ability EC50 at 175µg/ml are closely resembled to that of the standard drug ascorbic acid. The antioxidant activity also supported by the evaluation of the total phenolic compounds 235 µg/ml Gallic acid equivalent and flavonoids 210µg/ml as Quercetin Equivalent. S. chamaelea antioxidant activity may also support the herbal usage against vertigo, astringent, remedy for syphilis and diarrhoea.

Sri Venkateswara Zoological Park is a protected area of an ex-situ conservation for certain fauna and in-situ conservation of natural floral biodiversity comes under Sri Venkateswara Biospere Reserve Forest situated in the Seshachalam Hill ranges of Southern Eastern Ghats of Peninsular India. Floristic studies of protected areas is very much essential to enumerate the plant species for future generations and to maintain Sustainable Biodiversity Conservation. The systematic florist studies for three years resulted a total of 802 plant species include Bryophytes (2), Pteridophytes (13), Gymnosperms (5) along with major taxa of angiosperms (782) includes dicotyledons 639 and monocotyledons 143. Distribution of species to that of the other districts and regional floras showed a great diversity in the ratio of dicots to monocots equally to that of Kurnool and Chittoor Districts floras. Species diversity is closely related with Anantapur, Kurnool, Chittoor districts as the largest genera Euphorbia (15), Justicia (12) and Cyperus (10) and also with largest family Leguminosae (108) (Fabaceae). It also represents red listed species in natural conditions with Pterocarpus santalinus, Santalum album along with 11 other threatened category species in the zoo park. Hence, it is very essential to enumerate and enlist the flora of a protected area for the sustainable conservation for future generation.

Objectives: Many of the Fabaceae members are possessing anthelmintic property may be due to the presence of Phytoconstituents like tannins and phenolic compounds which acts as astringents against worm infestation. Hence A.aspera and A.indica were screened for their helminthic activity as used by the local herbalists. Materials and Methods: Plant materials A.aspera and A.indica were collected from Renigunta Mandal of Chittoor Dt, and identified as per Jain and Rao. Anthelmintic bioassay was carried out as per the Gosh method against Pheretima posthuma with leaf extracts. Results: A.aspera and A.indica leaf alcohol, methanol and aqueous extracts showed most effective anthelmintic activity than the standard drug Albendazole as in the time taken for paralysis and death. Out of all extracts A.aspera alcohol and methanol at 5, 10 and 15 mg proved its efficiency with in short time for paralysis 10-6 min and 20-11 min for death. Conclusion: A.aspera and A.indica aqueous, alcohol and methano...

The importance of antioxidant constituents in maintenance of health attracted research in plant based antioxidants. Presence of amino acid argenine and secondary metabolites like flavonoids and phenolic compounds and antibacterial activity leads for the evaluation of antioxidant activity of Sebastiania chamaelea leaf aqueous extracts. In-vitro free radical scavenging LC 50 at 100-90 µg/ml, and r educing ability EC50 at 175µg/ml are closely resembled to that of the standard drug ascorbic acid. The antioxidant activity also supported by the evaluation of the total phenolic compounds 235 µg/ml Gallic acid equivalent and flavonoids 210µg/ml as Quercetin Equivalent. S. chamaelea antioxidant activity may also support the herbal usage against vertigo, astringent, remedy for syphilis and diarrhoea.

The herbal medicinal plant Pittosporum floribundum is a rare mountain tree species of Seshachalam Hill Ranges of Eastern Ghats. Local herbalists use this species in healing skin diseases, arthritis, inflammation, bronchitis, leprosy, narcotic and antidote to snake venom. Phytochemical screening reveals the presence of tannins, alkaloids, saponins, glycosides, fixed oils, steroids, flavonoids and phenols mainly in water, alcohol and methanol extracts of leaf, bark, seed and fruit. Methanol extracts of bark showed more effective inhibition zones against all selected bacterial strains and two fungal strains at 20-30mg/ml with 16-25mm Zone of Inhibition than leaf, seed and fruit. Minimum Inhibitory Concentration ranges between 0.312- 1.25 mg against all microbial strains.

Objective:For the past one decade herbal drugs have been played an important role in the pharmacognostic validation to prove their therapeutic efficiencies. Pharmaceutical industries are interested in the formulations of the drug designing and in the collection of the crude drugs. Hence every herbal drug has to be analyzed pharmacognostically for their authentication and by which adulteration and the purity of the drug may be checked properly. Herbal medicine Sebastiania chamaelea (Euphorbiaceae) is very much important in various drug formulations due to the presence of bioactive constituents like Alkaloids, tannins, lignins, phenols, flavonoids, terpenoids and glycosides by which showing effective antibacterial, antifungal, antioxidant, antidiarrhoeal, antidiabetic, anthelmintic and also proved no toxic on wistar albino rats. Hence the crude drug S.chamaelea has to be evaluated pharmacognostically for future design of drugs. Methods: Various parts like leaves, stem, root and fruits...