Location via proxy:   [ UP ]  
[Report a bug]   [Manage cookies]                
Skip to main content

Suha Al-Naimi

Giardia is a major cause of parasitic diarrhoea and inhabits the upper small intestine. It is transmitted by faecal-oral route. Trophozoites attach to the intestinal epithelium, inducing giardiasis. Two genetically distinct lineages... more
Giardia is a major cause of parasitic diarrhoea and inhabits the upper small intestine. It is transmitted by faecal-oral route. Trophozoites attach to the intestinal epithelium, inducing giardiasis. Two genetically distinct lineages (assemblages) cause the human disease. Our work suggests that Giardia supernatant influences the short circuit current (Isc) of Colorectal Adenocarcinoma cell line (CaCo-2). The loss of transepithelial flux in response to different inhibitors has raised the possibility of Giardia-secreted mediators. By Differential Interference Contrast microscopy (DIC), we observed a concordant modification of the CaCo-2 cells morphology after 24 hours incubation with Giardia supernatants at different dilutions. The intestinal cell size significantly decreased when incubated with parasite supernatant, with significant effects being mediated even at high dilution. SDS-PAGE analyses of supernatants identified a number of secreted proteins; showing a majority of such proteins conserved between the two assemblages but also a few assemblage A-specific soluble proteins. Proteomic identification of these potential mediators of pathology is now underway.
Our results show that Giardia secretes soluble mediators which may be able to exert effects even at low concentration and at sites such as the colon which are distal to the infection.
 MySpira is the world first augmented reality (AR) asthma inhaler training app; it enables children to learn asthma keywords, types of inhalers, the preparation of the inhaler and spacer, asthma triggers, and develop skills on how to use... more
 MySpira is the world first augmented reality (AR) asthma inhaler training app; it enables children to learn asthma keywords, types of inhalers, the preparation of the inhaler and spacer, asthma triggers, and develop skills on how to use an asthma inhaler effectively. All of these are compiled into an enjoyable 20-minute experience, introducing likable characters and tactile interactions, which incentivise the child to progress all the way through the learning experience. This  study aimed to compare the efficacy of the MySpira application to traditional educational material (e.g. leaflets and videos) to improve asthma treatment compliance, technique and user engagement amongst 110 schoolchildren, aged 6 to 13. The findings indicate that MySpira surpasses the traditional educational materials, specifically in terms of enjoyment rating, the use of different inhalers’ techniques, particularly in the younger group (aged 6-9 years). Therefore, MySpira may enhance the level of available ...
Background: The prevalence rate of children with Autism Spectrum Disorder (ASD) has increased significantly worldwide from 1/10000 in the early 90’s to 1/150 in 2009. The rise in ASD rate has concomitantly raised the awareness about the... more
Background: The prevalence rate of children with Autism Spectrum Disorder (ASD) has increased significantly worldwide from 1/10000 in the early 90’s to 1/150 in 2009. The rise in ASD rate has concomitantly raised the awareness about the disorder, and increased the demands for more research, support services, recreational resources and highly trained special education professionals. Moreover, it brought the call to action in individual countries to further investigate the local prevalence rate as well as the detailed demographic distribution of children with ASD within each country. In developing countries, this is still a challenging task. No information about ASD rate or distribution is available in the Gulf countries, including Qatar. Despite the fact that the state of Qatar has started the initiative of setting the world autism awareness day (WAAD), rate and demographic distribution of children with ASD in Qatar is yet to be established. There is no central ASD database to quanti...
The electrical conduction of pristine (undoped) and iodine doped vacuum deposited films of the novel donors, dibenzodithiotetra-thionaphthalene and dibenzodithiotetraselenonaphthalene were measured. The electronic structures of these... more
The electrical conduction of pristine (undoped) and iodine doped vacuum deposited films of the novel donors, dibenzodithiotetra-thionaphthalene and dibenzodithiotetraselenonaphthalene were measured. The electronic structures of these donor compounds were examined experimentally by ultraviolet photoelectron spectroscopy and theoretically by semiempirical MO calculations and compared with the corresponding data of tetrathiotetracene.