I. Bilge
Koç University, Pediatric Nephrology & rheumatology, Faculty Member
Research Interests:
Secondary hyperparathyroidism (SHPT) has been better treated over the last decades, but the rate of metastatic calcifications, which were rarely seen before, was significantly increased in dialysis patients. The presence of uncontrolled... more
Secondary hyperparathyroidism (SHPT) has been better treated over the last decades, but the rate of metastatic calcifications, which were rarely seen before, was significantly increased in dialysis patients. The presence of uncontrolled SHPT, disorders of calcium (Ca) and phosphorus homeostasis and the common usage of large doses of vitamin D and Ca- containing phosphate binders may all contribute to the metastatic calcifications of soft tissues and vasculature leading to some life-threatening complications. Although the metastatic lung, heart, kidney, intestinal wall, skin, eye and soft tissue calcifications have been commonly reported in adults and also in children undergoing dialysis, the central nervous system calcification is a very rare condition. We report here a pediatric hemodialysis patient who presented with severe neurological findings due to the metastatic brain calcification secondary to his uncontrolled hyperparathyroidism.
Research Interests:
Renal candidiasis in the neonate is encountered infrequently. We report a newborn with ichthyosis, who during the hospital course had five episodes of culture-proven sepsis, probably due to skin lesions. For these infections various... more
Renal candidiasis in the neonate is encountered infrequently. We report a newborn with ichthyosis, who during the hospital course had five episodes of culture-proven sepsis, probably due to skin lesions. For these infections various antibiotic combinations were used. During the therapy of the last sepsis attack, unilateral hydronephrosis developed secondary to renal candidiasis. Percutaneous nephrostomy with amphotericin B irrigation, coupled with five weeks of intravenous amphotericin B therapy was successful. We believe that with this approach the mortality and morbidity of renal candidiasis could be reduced.
Research Interests:
Research Interests: Pediatrics, Adolescent, Humans, Child, Female, and 3 moreMale, Methylprednisolone, and Child preschool
Research Interests:
... Mecmuasl 63:1, 2000 BOBREK TRANSPLANTASYONU YAPIL1\/us en: 0LG_U]_)A TAC_RQLIMUSv(FK506) _KULLANIMINA_BAGLI (;1_1<;1c_1 INSULINE BAGIMLI nntnnrns MELLITUS GELI$IMI Ilmay BiLGE, Faruk OKTEM, Firdevs BA§, Aydan §iRiN, Seving EMRE,... more
... Mecmuasl 63:1, 2000 BOBREK TRANSPLANTASYONU YAPIL1\/us en: 0LG_U]_)A TAC_RQLIMUSv(FK506) _KULLANIMINA_BAGLI (;1_1<;1c_1 INSULINE BAGIMLI nntnnrns MELLITUS GELI$IMI Ilmay BiLGE, Faruk OKTEM, Firdevs BA§, Aydan §iRiN, Seving EMRE, Ahmet ...
Background: We aimed to review our experience with childhood lupus nephritis (LN) in respect to the analysis of the clinical and histopathological presentation of LN and prognostic factors affecting the kidney and patient outcomes.... more
Background: We aimed to review our experience with childhood lupus nephritis (LN) in respect to the analysis of the clinical and histopathological presentation of LN and prognostic factors affecting the kidney and patient outcomes. Method: Forty-three children (39 girls, 4 boys) ...
Research Interests:
Research Interests: Functional Analysis, Computational Biology, Cercopithecus aethiops, Cell line, Humans, and 15 moreChild, Computer Simulation, Kidney, Animals, Negative Feedback, Endoplasmic Reticulum, Pediatric Nephrology, Pediatric, Chronic Renal Failure, Congenital Anomalies, Transfection, Subcellular Fractions, Lysosomes, Epitopes, and Paediatrics and reproductive medicine
Research Interests: Turkey, Adolescent, Biopsy, Humans, Child, and 14 moreFemale, Male, Infant, Pediatric Nephrology, Serum Creatinine, Chronic Renal Failure, Nordic countries, Retrospective Studies, Chronic Kidney Failure, Vesicoureteral Reflux, Age at Onset, Glomerular Filtration Rate, Child preschool, and Paediatrics and reproductive medicine
Research Interests:
Research Interests: Humans, Child, Female, Male, Polymerase Chain Reaction, and 14 moreInfant, Pediatric Nephrology, Risk factors, Renal Function, Gene Polymorphism, Prognosis, Genetic Polymorphism, Disease Progression, Risk Factors, Angiotensin Converting Enzyme, Nephrotic syndrome, Focal Segmental Glomerulosclerosis, Child preschool, and Paediatrics and reproductive medicine
Research Interests: Adolescent, STEROIDS, Fibrinogen, Humans, Child, and 15 moreDeep Vein Thrombosis, Female, Drug Resistance, Male, Infant, Pediatric Nephrology, Thromboembolism, Hemostasis, Proteinuria, Renal disease, Control Group, Nephrotic syndrome, Serum albumin, Child preschool, and Paediatrics and reproductive medicine
Research Interests: Phosphorus, Humans, Magnesium, Female, Male, and 14 morePediatric Nephrology, Parathyroid Hormone, Alkaline phosphatase, Recurrence, Biological markers, Bone Formation, Bone and Bones, Glucocorticoids, Nephrotic syndrome, Cumulant, Glomerular Filtration Rate, Child preschool, Prednisone, and Paediatrics and reproductive medicine
Renal manifestations associated with infective endocarditis (IE) may present with different clinical patterns, and the most common renal histopathological finding is diffuse proliferative and exudative type of glomerulonephritis, leading... more
Renal manifestations associated with infective endocarditis (IE) may present with different clinical patterns, and the most common renal histopathological finding is diffuse proliferative and exudative type of glomerulonephritis, leading to hematuria and/or proteinuria. Renal failure due to crescentic glomerulonephritis (CGN) in children with IE is a very rare condition. We report here a 6-year-old boy, who had a history of cardiac surgery for pulmonary atresia and ventricular septal defect, presenting with the clinical findings of IE and hematuria associated with renal failure due to CGN. He was treated with a combination of intravenous (IV) methylprednisolone pulses and appropriate antibiotics, but also received one dose of IV cyclophosphamide. Complete serological, biochemical, and clinical improvement was achieved after 2 months of follow-up. Antibiotic therapy is the essential part of the treatment of IE-associated glomerulonephritis; however, this case also highlights the importance of aggressive immunosuppressive therapy to suppress the immunological process related with infection in this life-threatening condition leading to renal failure.
Research Interests:
... Page 2. Bilge I., Kiyak A., Naylr A., Ozgelik G., Kozok Y., Emre S., fiirin A. mg/dl, alkalen fosfataz: 1482 IU, parathor-mon: 792,7 ng/ml). ... Page 4. Bilge I., Kiyak A., Naylr A., Dzcelik G., Kozok Y.,Emre S., Sirin A. agir formu... more
... Page 2. Bilge I., Kiyak A., Naylr A., Ozgelik G., Kozok Y., Emre S., fiirin A. mg/dl, alkalen fosfataz: 1482 IU, parathor-mon: 792,7 ng/ml). ... Page 4. Bilge I., Kiyak A., Naylr A., Dzcelik G., Kozok Y.,Emre S., Sirin A. agir formu olan brown tfimorii dahi gortile-bilir (12). ...
Research Interests: Medical Genetics, Adolescent, Biological Sciences, Humans, Child, and 15 moreMutation, genetic Counselling, Female, Male, Infant, Aged, Middle Aged, Adult, Cohort Studies, Medical, Focal Segmental Glomerulosclerosis, DNA mutational analysis, Child preschool, Medical and Health Sciences, and Environmental factor
Research Interests: Adolescent, Prospective studies, Humans, Child, Europe, and 15 moreFemale, Male, Infant, Antibiotic Prophylaxis, Registries, Clinical Sciences, Odds ratio, Peritoneal Dialysis, Age Factors, Combination drug therapy, Chi Square Distribution, Peritonitis, Logistic Models, Prospective Study, and Child preschool
... (14:44) Kazada hastane masrafı SGK&#x27;dan. (14:36) Kolesterol tedavisinde yeni umut. (14:01) Estetikle güzelleşmenin sırrı &#x27;&#x27;doğallıkta&#x27;&#x27; gizli. ... REVIEW. Childhood Vasculitis And Kidneys... more
... (14:44) Kazada hastane masrafı SGK&#x27;dan. (14:36) Kolesterol tedavisinde yeni umut. (14:01) Estetikle güzelleşmenin sırrı &#x27;&#x27;doğallıkta&#x27;&#x27; gizli. ... REVIEW. Childhood Vasculitis And Kidneys Dr. Ilmay Bilge a a Çocuk Nefrolojisi BD, İstanbul Universitesi,İstanbul Tıp Fakültesi,İSTANBUL. ...
Özet Çalışmanın amacı; son dönem böbrek yetersizliği (SDBY) tanısı ile izlenen ve en az bir yıldır standart oral kalsitiriol tedavisi uygulandığı halde tedaviye dirençli bulunan, semptomatik, persistan sekonder hiperparatiroidizmli (SHPT)... more
Özet Çalışmanın amacı; son dönem böbrek yetersizliği (SDBY) tanısı ile izlenen ve en az bir yıldır standart oral kalsitiriol tedavisi uygulandığı halde tedaviye dirençli bulunan, semptomatik, persistan sekonder hiperparatiroidizmli (SHPT) hemodiyaliz tedavisindeki ...
Akut dissemine ensefalomiyelite bağlı nörojen mesane çocukluk çağında ender görülmektedir. Benzer bulguları verebilen akut transvers miyelit, Guillain-Barre sendromu ile ayırıcı tanısının yapılması tedavi açısından önemlidir. Fonksiyon... more
Akut dissemine ensefalomiyelite bağlı nörojen mesane çocukluk çağında ender görülmektedir. Benzer bulguları verebilen akut transvers miyelit, Guillain-Barre sendromu ile ayırıcı tanısının yapılması tedavi açısından önemlidir. Fonksiyon kaybının olduğu ...
SUMMARY: Sadıkoğlu B, Dolar E, Bilge I, Ertuğrul T, Emre S, Ömeroğlu RE, Şirin A, Dindar A, Kılıçaslan I, Solakoğlu S. (Department of Pediatrics, İstanbul University İstanbul Medical Faculty, İstanbul, Turkey). A juvenile case with... more
SUMMARY: Sadıkoğlu B, Dolar E, Bilge I, Ertuğrul T, Emre S, Ömeroğlu RE, Şirin A, Dindar A, Kılıçaslan I, Solakoğlu S. (Department of Pediatrics, İstanbul University İstanbul Medical Faculty, İstanbul, Turkey). A juvenile case with overlap syndrome consisting of ...
Research Interests:
We evaluated the frequency of renal malformations in relation to nonmosaic 45,X (group A, 45 patients, 54.9%) and mosaic/structural abnormalities of X (group B, 37 patients, 45.1%) in 82 Turkish patients with Turner syndrome (TS).... more
We evaluated the frequency of renal malformations in relation to nonmosaic 45,X (group A, 45 patients, 54.9%) and mosaic/structural abnormalities of X (group B, 37 patients, 45.1%) in 82 Turkish patients with Turner syndrome (TS). Ultrasonography of the kidneys and collecting system was performed in all patients. Of the 82 patients, 31 had different renal malformations (37.8%). Horse-shoe kidney was observed in 9 (29.0%) of the 31 patients, and 17 patients (54.8%) had various collecting system malformations, while 5 (16.2%) had malrotation and other positional abnormalities. The prevalence of renal malformations was significantly higher in group A (51.1%) than group B (21.6%) (2:7.94, P&lt;0.05). Although 8 of the 9 patients with horse-shoe kidney had the 45,X karyotype, collecting system malformations were observed more frequently in group B. Recurrent urinary tract infections (UTIs) were detected during follow-up in 7 patients, and hypertension developed in 3 patients. In patients who had a normal baseline nephrological evaluation, no problem suggesting renal disease developed during follow-up. We conclude that all forms of TS should have routine nephrological screening on diagnosis, since structural malformations of the kidney occur more frequently in nonmosaic 45,X TS, while collecting system malformations are mostly seen in mosaic/structural X forms. Those included in the group for nephrological follow-up had an increased risk for hypertension and/or UTI.