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Article
Mediating role of root-exuded secondary metabolites in intraspecific interactions with Haloxylon ammodendron
Root exudates are pivotal in soil carbon and nutrient cycling, enhancing nutrient availability and plant resource utilization efficiency under stress. Despite challenges in obtaining accurate soil-borne signal...
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Article
3D-QSAR modeling of Phosphodiesterase-5 inhibitors: evaluation and comparison of the receptor- and ligand-based alignments
Phosphodiesterase-5 (PDE5) inhibitors can be used as clinical agents for the treatment of erectile dysfunction and pulmonary hypertension. A series of aryl-chromeno-pyrrol derivatives were previously identifie...
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Article
Docking-assisted 3D-QSAR studies on xanthones as α-glucosidase inhibitors
Recently, a series of xanthone analogues has been identified as α-glucosidase inhibitors. To provide deeper insight into the three-dimensional (3D) structural requirements for the activities of these molecules, C...
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Article
Efficient preparation of trans-α,β-unsaturated aldehydes from saturated aldehydes by oxidative enamine catalysis
A mild and highly efficient amine-catalyzed, IBX-mediated oxidation of aldehydes to (E) selective α,β-unsaturated aldehydes has been achieved in good yields. The process features a new oxidation of enamines to im...