-
Article
Open AccessT. gondii excretory proteins promote the osteogenic differentiation of human bone mesenchymal stem cells via the BMP/Smad signaling pathway
Bone defects, resulting from substantial bone loss that exceeds the natural self-healing capacity, pose significant challenges to current therapeutic approaches due to various limitations. In the quest for alt...
-
Article
Open AccessCan holographic optical storage displace Hard Disk Drives?
Cloud data workloads require both high capacity at low cost and high access rates. Hard Disk Drives are the dominant media in this application as they are low cost, however, Hard Disk Drive technology is seein...
-
Article
Diabetes, glycemic control and arterial stiffness: a real-world cohort study in the context of predictive, preventive, and personalized medicine
Arterial stiffness is a major contributor to morbidity and mortality worldwide. Although several metabolic markers associated with arterial stiffness have been developed, there is limited data regarding whethe...
-
Article
Open AccessIdentification and evaluation of circulating exosomal miRNAs for the diagnosis of postmenopausal osteoporosis
Postmenopausal osteoporosis (PMOP) is a common condition that leads to a loss of bone density and an increased risk of fractures in women. Recent evidence suggests that exosomal miRNAs are involved in regulati...
-
Article
Open AccessInhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis
Osteoarthritis (OA) is an inflammatory disease of the joints that causes progressive disability in the elderly. Reactive oxygen species (ROS) play an important role in OA development; they may activate the NLR...
-
Article
Aloin promotes osteogenesis of bone-marrow-derived mesenchymal stem cells via the ERK1/2-dependent Runx2 signaling pathway
Osteoporosis is characterized by low bone mass and the degeneration of bone structure, conditions which increase the risk of fracture. Aloin has been shown to affect bone metabolism, but its role in osteogenic...
-
Article
Open AccessOff-axis points encoding/decoding with orbital angular momentum spectrum
Encoding/decoding off-axis points with discrete orbital angular momentum (OAM) modes is investigated. On-axis Laguerre-Gaussian (LG) beams are expanded into off-axis OAM spectra, with which off-axis points are...
-
Article
Erratum to: Glycogen synthase kinase 3 (GSK3)-inhibitor SB216763 promotes the conversion of human umbilical cord mesenchymal stem cells into neural precursors in adherent culture
-
Article
Glycogen synthase kinase 3 (GSK3)-inhibitor SB216763 promotes the conversion of human umbilical cord mesenchymal stem cells into neural precursors in adherent culture
The ability to generate neural progenitor cells from human umbilical cord mesenchymal stem cells (hUC-MSCs) has provided an option to treat neurodegenerative diseases. To establish a method for this purpose, w...