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Open AccessLow-density lipoprotein receptor promotes crosstalk between cell stemness and tumor immune microenvironment in breast cancer: a large data-based multi-omics study
Tumor cells with stemness in breast cancer might facilitate the immune microenvironment’s suppression process and led to anti-tumor immune effects. The primary objective of this study was to identify potential...
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Open AccessSelf-adaptive subgradient extragradient method with inertial modification for solving monotone variational inequality problems and quasi-nonexpansive fixed point problems
In this paper, we introduce a new algorithm with self-adaptive method for finding a solution of the variational inequality problem involving monotone operator and the fixed point problem of a quasi-nonexpansiv...
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Open AccessTranscriptomic but not genomic variability confers phenotype of breast cancer stem cells
Breast cancer stem cells (BCSCs) are considered responsible for cancer relapse and drug resistance. Understanding the identity of BCSCs may open new avenues in breast cancer therapy. Although several discoveri...
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Open AccessNew insights from the widening homogeneity perspective to target intratumor heterogeneity
Precision medicine has shed new light on the treatment of heterogeneous cancer patients. However, intratumor heterogeneity strongly constrains the clinical benefit of precision medicine. Thus, rethinking thera...