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Open AccessEffect of oral administration of microcin Y on growth performance, intestinal barrier function and gut microbiota of chicks challenged with Salmonella Pullorum
The lasso peptide microcin Y (MccY) effectively inhibits various serotypes of Salmonella in vitro, but the antibacterial effect against S. Pullorum in poultry is still unclear. This study was the first to evaluat...
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Article
Open AccessHydrogen gas inhalation ameliorates LPS-induced BPD by inhibiting inflammation via regulating the TLR4–NFκB–IL6/NLRP3 signaling pathway in the placenta
Hydrogen (H2) is regarded as a novel therapeutic agent against several diseases owing to its inherent biosafety. Bronchopulmonary dysplasia (BPD) has been widely considered among adverse pregnancy outcomes, witho...
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Open AccessCorrection: A risk prediction model for postoperative recovery of closed calcaneal fracture: a retrospective study
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Open AccessLongitudinal changes in body mass index, height, and weight in children with acute myeloid leukemia
This study reported height prediction and longitudinal growth changes in Chinese pediatric patients with acute myeloid leukemia (AML) during and after treatment and their associations with outcomes.
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Article
Open AccessArthroscopic surgery for ankle gouty arthritis: a retrospective analysis of clinical outcomes at six month follow-up based on a novel classification system
This study aimed to evaluate the clinical outcomes, patient-reported outcomes, and recurrence rate of patients diagnosed with ankle gouty arthritis who underwent arthroscopic surgery based on the new classific...
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Article
A comparison of the postoperative outcomes between intraoperative leak testing and no intraoperative leak testing for gastric cancer surgery: a systematic review and meta-analysis
Postoperative anastomotic leakage (PAL) is a serious complication of gastric cancer surgery. Although perioperative management has made considerable progress, anastomotic leakage (AL) cannot always be avoided....
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Article
A nomogram based on 4-lncRNAs signature for improving prognostic prediction of hepatocellular carcinoma
Long noncoding RNAs (lncRNAs) with abnormal expression are frequently seen in hepatocellular cancer patients (HCC). Previous studies have reported the correlation between lncRNA and prognosis processes of HCC ...
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Article
A potential novel biomarker: comprehensive analysis of prognostic value and immune implication of CES3 in colonic adenocarcinoma
Colon cancer is the most common malignant tumor in the intestine. Abnormal Carboxylesterases 3 (CES3) expression had been reported to be correlated to multiple tumor progression. However, the association among...
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Article
Nd-Mn Molecular Cluster with Searched Targets for Oral Cancer Imaging
In this research, we designed a novel NIR II luminescence imaging probe with targeting effect to accurately track oral squamous cell carcinoma (OSCC) cells. Massive gene expression data were processed by weigh...
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Article
Open AccessPatient-reported outcome measures in functional dyspepsia: a systematic review and COSMIN analysis
Functional dyspepsia (FD) as a type of disorders of brain-gut interaction (DBGI), patient self-reporting of its symptoms becomes an important component of clinical outcome assessment. We performed a systematic...
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Article
Open AccessCharacteristics of brittle cornea syndrome by multimodal imaging modalities: a case report
A report of a Brittle cornea syndrome (BCS) case with bluish scleral discoloration, keratoglobus, and myopia based on multimodal imaging modalities including in vivo confocal microscopy (IVCM), high-definition...
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Open AccessHeavy metals in drinking water and periodontitis: evidence from the national oral health survey from China
Periodontitis has become an increasingly important public health issue, coupled with a high economic burden for prevention and treatment. Exposure to essential trace heavy metals has been associated with vario...
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Article
Open AccessA risk prediction model for postoperative recovery of closed calcaneal fracture: a retrospective study
To explore the risk factors for postoperative recovery of closed calcaneal fracture and develop a prediction model.
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Article
Open AccessKnowledge fields and emerging trends about extracellular matrix in carotid artery disease from 1990 to 2021: analysis of the scientific literature
Stroke is a heavy burden in modern society, and carotid artery disease is a major cause. The role of the extracellular matrix (ECM) in the development and progression of carotid artery disease has become a pop...
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Article
Open AccessEtiological and clinical characteristics of severe pneumonia in pediatric intensive care unit (PICU)
To analyze the etiological distribution characteristics of pediatric patients with severe pneumonia admitted to the Pediatric Intensive Care Unit (PICU), in order to provide a reference for the rational use of...
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Article
Open AccessRisk factors for perioperative acute heart failure in older hip fracture patients and establishment of a nomogram predictive model
This study aims to explore the risk factors for perioperative acute heart failure in older patients with hip fracture and establish a nomogram prediction model.
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Article
Open AccessVortioxetine hydrobromide inhibits the growth of gastric cancer cells in vivo and in vitro by targeting JAK2 and SRC
Gastric cancer is the fourth leading cause of cancer deaths worldwide. Most patients are diagnosed in the advanced stage. Inadequate therapeutic strategies and the high recurrence rate lead to the poor 5-year ...
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Article
Eltrombopag in severe immune thrombocytopenia secondary to connective tissue disease: a report of 17 patients and literature review
To assess the remission rate of eltrombopag in the treatment of severe immune thrombocytopenia (ITP) secondary to connective tissue disease (CTD) and to explore factors related to drug efficacy in the context ...
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Article
Global status and trends in gout research from 2012 to 2021: a bibliometric and visual analysis
Gout is the most common inflammatory arthritis with an increasing prevalence and incidence across the globe. We aimed to provide a comprehensive and systematic knowledge map of gout research to determine its c...
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Article
Open AccessImpact of dysautonomic symptom burden on the quality of life in Neuromyelitis optica spectrum disorder patients
This study aimed to investigate the clinical risk factors of dysautonomic symptom burden in neuromyelitis optica spectrum disorder (NMOSD) and its impact on patients’ quality of life.