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796 Result(s)
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Article
Open AccessDuck CD40L as an adjuvant enhances systemic immune responses of avian flavivirus DNA vaccine
Under the dual pressure of emerging zoonoses and the difficulty in eliminating conventional zoonoses, the strategic management of bird diseases through vaccination represents a highly efficacious approach to d...
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Diagnostic performance of radiomics for predicting arterial plaque vulnerability: a systematic review and meta-analysis
Radiomics, in which medical images are analysed by extracting a large number of quantitative features, and is being increasingly applied in clinical research regarding medical imaging analysis. The aim of this...
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Open AccessA cellular senescence-related signature for predicting prognosis, immunotherapy response, and candidate drugs in patients treated with transarterial chemoembolization (TACE)
Cellular senescence is essential to TME development, progression, and remodeling. Few studies have examined cellular senescence in HCC after TACE. Investigating the relationship between cellular senescence, po...
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Enhanced neurovascular dynamic model for exploring vasoconstriction induced by febrile seizures
Neurovascular coupling is a fundamental concept that elucidates how neuronal electrical activity regulates vascular function, ensuring optimal blood flow to active regions of the brain and optimizing neural fu...
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MET overexpression correlated with prognosis of EGFR-mutant treatment‑naïve advanced lung adenocarcinoma: a real‑world retrospective study
About 50–60% treatment-naïve advanced non-small-cell lung cancers were coexistence of epidermal growth factor receptor (EGFR) and mesenchymal epithelial transition (MET) overexpression. However, few studies de...
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Numerical modeling of ground surface settlement due to tunneling in urban areas
The rise in urban traffic challenges has spurred the expansion of subterranean transportation systems within metropolitan areas. In densely populated regions, surface settlement has emerged as a pivotal factor...
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Open AccessOptimal antiplatelet therapy after revascularization of left subclavian artery during TEVAR
Thoracic endovascular aortic repair (TEVAR) is a minimally invasive technique used to treat type B aortic dissections. Left subclavian artery (LSA) reconstruction is required when treating patients with involv...
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Open AccessDuck STING mediates antiviral autophagy directing the interferon signaling pathway to inhibit duck plague virus infection
Migratory birds are important vectors for virus transmission, how migratory birds recognize viruses and viruses are sustained in birds is still enigmatic. As an animal model for waterfowl among migratory birds...
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Open AccessReproductive concerns and its correlation with fear of recurrence and level of family support in patients of childbearing age with gynecologic malignancies
To discuss the current status of reproductive concerns and its correlation with fear of recurrence and level of family support in patients of childbearing age with gynecologic malignancies.
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Author Correction: Topological Wannier cycles induced by sub-unit-cell artificial gauge flux in a sonic crystal
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Rational design of biodegradable semiconducting polymer nanoparticles for NIR-II fluorescence imaging-guided photodynamic therapy
Semiconducting polymer nanoparticles (SPNs) have shown great promise in second near-infrared window (NIR-II) phototheranostics. However, the issue of long metabolic time significantly restricts the clinical ap...
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Open AccessMRI quantitative hemodynamic parameter histogram assement of hepatocellular carcinoma development in a rabbit VX2 liver cancer model
Nowadays, liver cancer is the second leading cause of cancer death in the world. Therefore, it is very important to understand tumor progression and evaluate tumor microcirculation for treatment strategy.
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Article
MYEOV with High Frequencies of Mutations in Head and Neck Cancers Facilitates Cancer Cell Malignant Behaviors
Cancer driver genes (CDGs) and the driver mutations disrupt the homeostasis of numerous critical cell activities, thereby playing a critical role in tumor initiation and progression. In this study, integrative...
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Article
Neuronal avalanche dynamics regulated by spike-timing-dependent plasticity under different topologies and heterogeneities
Neuronal avalanches, a critical state of network self-organization, have been widely observed in electrophysiological records at different signal levels and spatial scales of the brain, which has significant i...
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Open AccessThe value of lipid accumulation products in predicting type 2 diabetes mellitus: a cross-sectional study on elderlies over 65 in Shanghai
As lifestyle changes, there is an increasing number of type 2 diabetes mellitus (T2DM) patients in China. The present study aimed to investigate the predictive value of the lipid accumulation product (LAP) for...
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Open AccessHSP70 positively regulates translation by interacting with the IRES and stabilizes the viral structural proteins VP1 and VP3 to facilitate duck hepatitis A virus type 1 replication
The maintenance of viral protein homeostasis depends on the interaction between host cell proteins and viral proteins. As a molecular chaperone, heat shock protein 70 (HSP70) has been shown to play an importan...
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Open AccessInvestigation of the epidemiology, pathogenicity and immunogenicity of Bordetella bronchiseptica isolated from cats and dogs in China from 2021 to 2023
Bordetella bronchiseptica (Bb) is recognized as a leading cause of respiratory diseases in dogs and cats. However, epidemiological data on Bb in dogs and cats in China are still limited, and there is no commercia...
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Open AccessSequential glycosylations at the multibasic cleavage site of SARS-CoV-2 spike protein regulate viral activity
The multibasic furin cleavage site at the S1/S2 boundary of the spike protein is a hallmark of SARS-CoV-2 and plays a crucial role in viral infection. However, the mechanism underlying furin activation and its...
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Dynamical switchable quantum nonreciprocity induced by off-resonant chiral two-photon driving
Optical nonreciprocity, which refers to the direction-dependent emission, scattering and absorption of photons, plays a very important role in quantum engineering and quantum information processing. Here, we p...
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Multi-scale-space Grillage Mixed Method of Mechanical Behavior of Composite Box Beams with Finite Element Method (FEM)
Due to different composition materials, steel–concrete composite box beams have interface slip, shear deformation, and other characteristics. Composite box beams have significant spatial effects and complex me...