346 Result(s)
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Open AccessHypothesis paper: GDF15 demonstrated promising potential in Cancer diagnosis and correlated with cardiac biomarkers
Cardiovascular toxicity represents a significant adverse consequence of cancer therapies, yet there remains a paucity of effective biomarkers for its timely monitoring and diagnosis. To give a first evidence a...
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Probing dark matter particles from evaporating primordial black holes via electron scattering in the CDEX-10 experiment
Dark matter (DM) is a major constituent of the Universe. However, no definite evidence of DM particles (denoted as “χ”) has been found in DM direct detection (DD) experiments to date. There is a novel concept of ...
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Open AccessA novel protein encoded by circCOPA inhibits the malignant phenotype of glioblastoma cells and increases their sensitivity to temozolomide by disrupting the NONO–SFPQ complex
Glioblastoma (GBM) represents a primary malignant brain tumor. Temozolomide resistance is a major hurdle in GBM treatment. Proteins encoded by circular RNAs (circRNAs) can modulate the sensitivity of multiple ...
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Open AccessSpatial patterns of Geological Culture Villages (Towns) and their influential factors in China
Geological Culture Villages Towns (GCV(T)s) serve as rich repositories of geological resources, embodying significant historical and cultural values that mirror the dynamic interplay between Earth's evolution ...
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Open AccessBiologically interpretable multi-task deep learning pipeline predicts molecular alterations, grade, and prognosis in glioma patients
Deep learning models have been developed for various predictions in glioma; yet, they were constrained by manual segmentation, task-specific design, or a lack of biological interpretation. Herein, we aimed to ...
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Combined transcriptome and proteome analysis reveals MSN and ARFIP2 as biomarkers for trastuzumab resistance of breast cancer
HER2-positive breast cancer (BC) accounts for 20–30% of all BC subtypes and is linked to poor prognosis. Trastuzumab (Tz), a humanized anti-HER2 monoclonal antibody, is a first-line treatment for HER2-positive...
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Efficacy of antibiotic prophylaxis for reducing capsular contracture in prosthesis-based breast surgery: a systemic review and meta-analysis
Antibiotics Prophylaxis to prevent capsular contracture in prosthesis-based breast surgery is common in clinical practice. However, there is currently a dearth of high-quality evidence concerning the effective...
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Risk factors of missed early gastric cancer in endoscopic resected population: a retrospective, case–control study
Missed early gastric cancer (MEGC) is prevalent during esophagogastroduodenoscopy (EGD), which is the first-line recommended strategy for detecting early gastric cancer (EGC). Hence, we explored the risk facto...
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Open AccessA multi-Task Learning based applicable AI model simultaneously predicts stage, histology, grade and LNM for cervical cancer before surgery
To build an Mult-Task Learning (MTL) based Artificial Intelligence(AI) model that can simultaneously predict clinical stage, histology, grade and LNM for cervical cancer before surgery.
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Joint MEC selection and wireless resource allocation in 5G RAN
With the vigorous development of the Internet of Things (IoT), the demand for user equipment (UE) computing capacity is increasing. Multiaccess edge computing (MEC) provides users with high-performance and low...
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Open AccessMMP-3 mediates copper oxide nanoparticle-induced pulmonary inflammation and fibrosis
The increasing production and usage of copper oxide nanoparticles (Nano-CuO) raise human health concerns. Previous studies have demonstrated that exposure to Nano-CuO could induce lung inflammation, injury, an...
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Open AccessReversible modulation of superconductivity in thin-film NbSe2 via plasmon coupling
In recent years, lightwave has stood out as an ultrafast, non-contact control knob for developing compact superconducting circuitry. However, the modulation efficiency is limited by the low photoresponse of su...
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Quantitative trait locus analysis of gray leaf spot resistance in the maize IBM Syn10 DH population
The exploration and dissection of a set of QTLs and candidate genes for gray leaf spot disease resistance using two fully assembled parental genomes may help expedite maize resistance breeding.
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Open AccessMetagenomic next-generation sequencing promotes diagnosis and treatment of Pneumocystis jirovecii pneumonia in non-HIV infected children: a retrospective study
Metagenomic next-generation sequencing (mNGS) excels in diagnosis of infection pathogens. We aimed to evaluate the performance of mNGS for the diagnosis of Pneumocystis jirovecii pneumonia (PJP) in non-HIV infect...
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Open AccessIntercropping improves faba bean photosynthesis and reduces disease caused by Fusarium commune and cinnamic acid-induced stress
Modern intensive cropping systems often contribute to the accumulation of phenolic acids in the soil, which promotes the development of soilborne diseases. This can be suppressed by intercropping. This study a...
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Surface Anion Effects in Aqueous Hydrogen Ion Batteries
Aqueous hydrogen ion batteries possess the advantages of sustainability, low cost, and high safety, which makes them an ideal choice for grid-level energy storage. Although some anions show strong interaction ...
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Topological Kerr effects in two-dimensional magnets with broken inversion symmetry
The whorls of localized moments in chiral magnetic structures, such as skyrmions, lead to a quantized topological charge, which may make them useful as next-generation information bits. So far, the most reliab...
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Open AccessSimultaneous application of oral and intravaginal probiotics for Helicobacter pylori and its antibiotic-therapy-induced vaginal dysbacteriosis
Helicobacter pylori is a prevalent bacterial pathogen globally, implicated in various gastrointestinal disorders. Current recommended antibiotic therapies for H. pylori infection have been proven to be therapeuti...
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Open AccessCompletion rates and myelosuppression degrees of cancer patients receiving radiotherapy or chemoradiotherapy unchanged regardless of delay duration after Omicron infection
This study aimed to investigate impacts of Omicron infection on cancer patients in China. A retrospective study was conducted, including 347 cancer patients undergoing radiotherapy or chemoradiotherapy between...
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From Waste to Wealth: Current Advances in Recycling Technologies for Metal Recovery from Vanadium-Titanium Magnetite Tailings
The burgeoning accumulation of vanadium-titanium magnetite tailings (VTMT) presents a dual challenge of environmental hazard and loss of valuable metal resources. This review arrives at a crucial juncture in g...