4 Result(s)

Article

Correction: A high-resolution route map reveals distinct stages of chondrocyte dedifferentiation for cartilage regeneration

Yishan Chen, Yeke Yu, Ya Wen, Juan Chen, Junxin Lin, Zixuan Sheng… in Bone Research (2022)

Article

A high-resolution route map reveals distinct stages of chondrocyte dedifferentiation for cartilage regeneration

Articular cartilage damage is a universal health problem. Despite recent progress, chondrocyte dedifferentiation has severely compromised the clinical outcomes of cell-based cartilage regeneration. Loss-of-fun...

Yishan Chen, Yeke Yu, Ya Wen, Juan Chen, Junxin Lin, Zixuan Sheng… in Bone Research (2022)

Article

Engineered adipose-derived stem cells with IGF-1-modified mRNA ameliorates osteoarthritis development

Osteoarthritis (OA), a prevalent degenerative disease characterized by degradation of extracellular matrix (ECM), still lacks effective disease-modifying therapy. Mesenchymal stem cells (MSCs) transplantation ...

Haoyu Wu, Zhi Peng, Ying Xu, Zixuan Sheng, Yanshan Liu… in Stem Cell Research & Therapy (2022)

Article

Classification of four distinct osteoarthritis subtypes with a knee joint tissue transcriptome atlas

The limited molecular classifications and disease signatures of osteoarthritis (OA) impede the development of prediagnosis and targeted therapeutics for OA patients. To classify and understand the subtypes of ...

Chunhui Yuan, Zongyou Pan, Kun Zhao, Jun Li, Zixuan Sheng, Xudong Yao… in Bone Research (2020)