Histidin

l-Histidin
	; Rumus rangka histidin (wangun zwitterionik)
Modél bal jeung tongkat	Modél ngeusi rohang
Wasta
	Wasta IUPAC Histidin
	Wasta lian Asam 2-amino-3-(1H-imidazol-4-il)propanoat
Pananda
Nomer CAS	71-00-1 ;
Modél 3D (JSmol)	Gambar interaktif; Zwitterion: Gambar interaktif; Protonated zwitterion: Gambar interaktif;
ChEBI	CHEBI:15971 ;
ChEMBL	ChEMBL17962 ;
ChemSpider	6038 ;
DrugBank	DB00117 ;
ECHA InfoCard	100.000.678
IUPHAR/BPS	3310;
KEGG	D00032 ;
PubChem CID	6274;
UNII	4QD397987E ;
CompTox Dashboard (EPA)	DTXSID9023126 ;
	InChI InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1 Key: HNDVDQJCIGZPNO-YFKPBYRVSA-N ;
	SMILES O=C([C@H](CC1=CNC=N1)N)O; Zwitterion: O=C([C@H](CC1=CNC=N1)[NH3+])[O-]; Protonated zwitterion: O=C([C@H](CC1=CNC=[NH1+]1)[NH3+])[O-];
Sipat
Rumus kimia	C6H9N3O2
Massa molar	155157 g·mol−1
Kelarutan dina cai	4.19g/100g @ 25 °C
Baya
NFPA 704	1 1 0
	Iwal disebutkeun séjén, data nu dipidangkeun keur matéri dina kaayaan baku (dina 25 °C, 100 kPa).
	Rujukan kotak info

Histidin (lambang His atawa H)^[2] nyaéta asam α-amino ésénsial anu dipaké dina biosintésis protéin. Histidin ngandung gugus α-amino (wangun –NH₃⁺ diprotonasi dina kaayaan biologis), gugus asam karboksilat (wangun –COO⁻ deprotonasi dina kaayaan biologis), jeung ranté gigir imidazol (diprotonasi parsial), kaasup golongan asam amino muatan positip dina pH pisiologis. Mimitina dianggap ésénsial ukur keur orok, kadieunakeun kapanggih ésénsial ogé pikeun sawawa.^[3] Kode genetikna disandi ku kodon CAU jeung CAC.

Histidin munggaran diisolasi ku dokter Jérman Albrecht Kossel jeung Sven Gustaf Hedin taun 1896.^[4], mangrupakeun prékursor histamin, agén inflamatori pital dina réspon imun.

Baca ogé

Rujukan

↑ http://prowl.rockefeller.edu/aainfo/solub.htm Citakan:Full citation needed
↑ "Nomenclature and Symbolism for Amino Acids and Peptides". IUPAC-IUB Joint Commission on Biochemical Nomenclature. 1983. Diarsipkan dari versi asli tanggal 9 October 2008. Diakses tanggal 5 March 2018. Archived 9 Oktober 2008 di Wayback Machine
↑ Kopple, J D; Swendseid, M E (1975). "Evidence that histidine is an essential amino acid in normal and chronically uremic man". Journal of Clinical Investigation 55 (5): 881–91. doi:10.1172/JCI108016. PMC 301830. PMID 1123426. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=301830.
↑ Vickery, Hubert Bradford; Leavenworth, Charles S. (1928-08-01). "On the Separation of Histidine and Arginine" (dalam bahasa en). Journal of Biological Chemistry 78 (3): 627–635. doi:10.1016/S0021-9258(18)83967-9. ISSN 0021-9258. http://www.jbc.org/content/78/3/627.full.pdf.

Tutumbu kaluar

Histidine MS Spectrum

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[1] ttp://prowl.rockefeller.edu/aainfo/solub.htm Citakan:Full citation needed

[2] "Nomenclature and Symbolism for Amino Acids and Peptides". IUPAC-IUB Joint Commission on Biochemical Nomenclature. 1983. Diarsipkan dari versi asli tanggal 9 October 2008. Diakses tanggal 5 March 2018. Archived 9 Oktober 2008 di Wayback Machine

[3] Kopple, J D; Swendseid, M E (1975). "Evidence that histidine is an essential amino acid in normal and chronically uremic man". Journal of Clinical Investigation 55 (5): 881–91. doi:10.1172/JCI108016. PMC 301830. PMID 1123426. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=301830.

[4] Vickery, Hubert Bradford; Leavenworth, Charles S. (1928-08-01). "On the Separation of Histidine and Arginine" (dalam bahasa en). Journal of Biological Chemistry 78 (3): 627–635. doi:10.1016/S0021-9258(18)83967-9. ISSN 0021-9258. http://www.jbc.org/content/78/3/627.full.pdf.

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