Capítulo do livro "Cultura, Memória e Poder: História e Historiografia", organizado pelos Profess... more Capítulo do livro "Cultura, Memória e Poder: História e Historiografia", organizado pelos Professores Antônio Fernando de Araújo Sá e Bruno Gonçalves Alvaro e publicado pela Editora da UFPE. Analiso, sob o ponto de vista do paradigma indiciário, uma querela historiográfica que ocorreu no início do século XX nos quadros do IHGSP (Instituto Histórico e Geográfico de São Paulo) e que girou em torno da assinatura de João Ramalho conforme ficou grafada nas Atas da Câmara Municipal de Santo André, preservadas no período de 22 de julho de 1555 a 31 de março de 1558. A conclusão pode trazer alguma surpresa.
Revista Do Instituto De Medicina Tropical De Sao Paulo, 1998
A clinical trial pilot study, double-blinded, randomized, and controlled with a placebo to assess... more A clinical trial pilot study, double-blinded, randomized, and controlled with a placebo to assess the effectiveness of oral doxycycline (200 mg, single dose) in preventing leptospirosis after high exposure to potentially contaminated water was performed in São Paulo, SP, Brazil. Confirmed cases were defined as those with leptospira IgM antibody and symptoms; asymptomatic cases were those presenting with IgM antibodies but no symptoms; and suspected cases were individuals with symptoms but no IgM antibody. Forty subjects were given doxycycline and 42 were given placebo. In the drug-treated group there were 2 confirmed cases, 11 asymptomatic cases, and 6 suspected cases. In the placebo group there were 5 confirmed, 6 symptomatic, and 5 suspected cases. Even though we found a protective association of doxycycline for confirmed leptospirosis cases (RR = 2.3) and seroconversion only (RR = 2.0), the association was not statistically significant because of the small number of individuals enrolled in this pilot study. We observed that the 22% of the volunteers already had IgM antibodies to leptospirosis at the first sampling. Finally, the attack rate to confirmed, asymptomatic, and suspected cases of Leptospirosis was 8.5%, 22%, and 13%, respectively, in this population.
Capítulo do livro "Cultura, Memória e Poder: História e Historiografia", organizado pelos Profess... more Capítulo do livro "Cultura, Memória e Poder: História e Historiografia", organizado pelos Professores Antônio Fernando de Araújo Sá e Bruno Gonçalves Alvaro e publicado pela Editora da UFPE. Analiso, sob o ponto de vista do paradigma indiciário, uma querela historiográfica que ocorreu no início do século XX nos quadros do IHGSP (Instituto Histórico e Geográfico de São Paulo) e que girou em torno da assinatura de João Ramalho conforme ficou grafada nas Atas da Câmara Municipal de Santo André, preservadas no período de 22 de julho de 1555 a 31 de março de 1558. A conclusão pode trazer alguma surpresa.
Revista Do Instituto De Medicina Tropical De Sao Paulo, 1998
A clinical trial pilot study, double-blinded, randomized, and controlled with a placebo to assess... more A clinical trial pilot study, double-blinded, randomized, and controlled with a placebo to assess the effectiveness of oral doxycycline (200 mg, single dose) in preventing leptospirosis after high exposure to potentially contaminated water was performed in São Paulo, SP, Brazil. Confirmed cases were defined as those with leptospira IgM antibody and symptoms; asymptomatic cases were those presenting with IgM antibodies but no symptoms; and suspected cases were individuals with symptoms but no IgM antibody. Forty subjects were given doxycycline and 42 were given placebo. In the drug-treated group there were 2 confirmed cases, 11 asymptomatic cases, and 6 suspected cases. In the placebo group there were 5 confirmed, 6 symptomatic, and 5 suspected cases. Even though we found a protective association of doxycycline for confirmed leptospirosis cases (RR = 2.3) and seroconversion only (RR = 2.0), the association was not statistically significant because of the small number of individuals enrolled in this pilot study. We observed that the 22% of the volunteers already had IgM antibodies to leptospirosis at the first sampling. Finally, the attack rate to confirmed, asymptomatic, and suspected cases of Leptospirosis was 8.5%, 22%, and 13%, respectively, in this population.
Uploads
Papers by Marcos Silva
Books by Marcos Silva