This study was undertaken to compare the cost effectiveness of two vacuum-assisted breast biopsy devices, the Mammotome and Vacora systems. Between January and June 2006, 238 vacuum-assisted breast biopsies were performed at our radiology... more
This study was undertaken to compare the cost effectiveness of two vacuum-assisted breast biopsy devices, the Mammotome and Vacora systems. Between January and June 2006, 238 vacuum-assisted breast biopsies were performed at our radiology department. Five out of 238 lesions were excluded because of inadequate sampling. The Mammotome system was used in 108/233 lesions and the Vacora system in 125/233. Fifty-eight lesions underwent ultrasound-guided breast biopsy, and 50 lesions underwent mammography-guided biopsy with both Mammotome and Vacora devices. Magnetic-resonance-guided biopsy was possible with the Vacora system only (17/125 lesions). All procedures were successfully completed. No significant differences were found between the results of the Mammotome and Vacora biopsies in terms of effectiveness: sensitivity was 84.4% and 86.2%, respectively, and specificity 100%. In terms of cost, the Mammotome system has higher costs per procedure compared with the Vacora. Our clinical results confirm the diagnostic accuracy of both the Mammotome and Vacora systems, whereas our cost analysis shows that there is a considerable difference, mostly related to the initial investment.
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Il presente studio si propone di individuare un protocollo analitico per la validazione dei procedimenti di restauro conservativo della pergamena, che vede l'azione congiunta di conservatori, restauratori e ricercatori. Il metodo... more
Il presente studio si propone di individuare un protocollo analitico per la validazione dei procedimenti di restauro conservativo della pergamena, che vede l'azione congiunta di conservatori, restauratori e ricercatori. Il metodo adottato consiste in un esame multiscala basato su indagini non-invasive e micro-invasive per caratterizzare le proprietà morfologiche, strutturali e fisico-chimiche della pergamena nuova e di quella sottoposta a trattamenti di invecchiamento artificiale seguiti da operazioni di restauro conservativo come umidificazione diretta con soluzioni idroalcoliche di differenti concentrazioni; ammorbidimento con polietilenglicole e con soluzione acquosa di alcol etilico, urea e cloruro sodico, con crema protettiva a base di lanolina e Bibliobalsamo®crema Frati&Livi, ecc. Le pergamene nuove ottenute presso INCDTP-ICPI di Bucarest sono state precedentemente sottoposte a trattamenti termici mediante radiazione (flussi di calore: 20kW/m 2 e 80 kW/m 2) e convezione (...
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Micro DSC measurements were used to investigate the synergistic effects of temperature and relative humidity on deterioration of parchment. Samples were obtained by exposing new parchments to various temperature and relative humidity... more
Micro DSC measurements were used to investigate the synergistic effects of temperature and relative humidity on deterioration of parchment. Samples were obtained by exposing new parchments to various temperature and relative humidity atmospheres for increasing times in controlled test chambers. The impact of this accelerated ageing was assessed by measuring the thermodynamic parameters associated with the thermal denaturation of fibrillar collagen: variation of denaturation temperature. T-max, indicated changes in collagen thermal stability, increases of DSC peak half-width, Delta T-1/2, revealed greater thermal heterogeneity and structural disorder, whereas parallel decrease of denaturation enthalpy Delta H, and DSC peak maximum height, C-p(ex) max, measured the loss of fibrillar structure. Deconvolution of DSC denaturation peaks provided a valuable illustration of both the dynamics and the pattern of the deterioration of fibrillar collagen. Impact of temperature and relative humid...
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In the last decade differential scanning calorimetry (DSC) has emerged as a powerful technique for minimally invasive characterisation of damage and quantification of environmental risk in parchment historical and archaeological... more
In the last decade differential scanning calorimetry (DSC) has emerged as a powerful technique for minimally invasive characterisation of damage and quantification of environmental risk in parchment historical and archaeological artefacts. The possibility to determine which objects are most environmentally sensitive and to quantify deterioration from samples as small as a very few square millimeters, i.e. corresponding to 2-4 mg of material, has opened systematic studies on the effects of degrading environment as well as on individual historical objects and entire collections of objects, thus significantly impacting our understanding of parchments deterioration and alerting conservators to their susceptibility to indoor factors. Following our particular interest along the last decade on the physical-chemical assessment of parchment, we review and complete the DSC data on new, artificially aged and historical parchments and highlight the mechanisms and dynamics of their artificial an...
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