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    In this study, municipal plastic waste is used in producing paving blocks. Binders in the form of melted waste plastic bottles (Polyethelene Terephthalate (PET)) and water sachets (High Density Polyethylene (HDPE) with river sand, were... more
    In this study, municipal plastic waste is used in producing paving blocks. Binders in the form of melted waste plastic bottles (Polyethelene Terephthalate (PET)) and water sachets (High Density Polyethylene (HDPE) with river sand, were used in making the blocks. Mix ratios; 1:1, 1:1.5 and 1:2 of sand-plastic waste were considered. Sand-cement mixes were adopted as the controls. 230mm x 140mm x 55mm blocks were cast, cured in water at ambient temperature and tested for 72-hours for water absorption and 21 days compressive strength. 3 specimen were prepared for each mixture. Sand-HDPE mix produced stronger blocks than sand-PET and sand-cement mixes. Topmost compressive strength of 17N/mm2 was generated from sand-HDPE mix of 1:2. Sand-PET blocks should be avoided since they generate very low strengths. Sand-plastic waste blocks melt faster at higher temperatures. Therefore, plastic paving blocks can only be used for light load pavements not subjected to high temperature.
    Background We aimed to characterize etanercept (ETN) use in juvenile idiopathic arthritis (JIA) patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. Methods The CARRA Registry is a convenience... more
    Background We aimed to characterize etanercept (ETN) use in juvenile idiopathic arthritis (JIA) patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. Methods The CARRA Registry is a convenience cohort of patients with paediatric onset rheumatic diseases, including JIA. JIA patients treated with ETN for whom the month and year of ETN initiation were available were included. Patterns of ETN and methotrexate (MTX) use were categorized as follows: combination therapy (ETN and MTX started concurrently), step-up therapy (MTX started first and ETN added later), switchers (MTX started and then stopped when or before ETN started), MTX add-on (ETN started first and MTX added later), and ETN only (no MTX use). Data were described using parametric and non-parametric statistics as appropriate. Results Two thousand thirty-two of the five thousand six hundred forty-one patients with JIA met inclusion criteria (74% female, median age at diagnosis 6.0 year...
    Background Social determinants of health (SDH) greatly influence outcomes during the first year of treatment in rheumatoid arthritis, a disease similar to polyarticular juvenile idiopathic arthritis (pJIA). We investigated the correlation... more
    Background Social determinants of health (SDH) greatly influence outcomes during the first year of treatment in rheumatoid arthritis, a disease similar to polyarticular juvenile idiopathic arthritis (pJIA). We investigated the correlation of community poverty level and other SDH with the persistence of moderate to severe disease activity and functional disability over the first year of treatment in pJIA patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance Registry. Methods In this cohort study, unadjusted and adjusted generalized linear mixed effects models analyzed the effect of community poverty and other SDH on disease activity, using the clinical Juvenile Arthritis Disease Activity Score-10, and disability, using the Child Health Assessment Questionnaire, measured at baseline, 6, and 12 months. Results One thousand six hundred eighty-four patients were identified. High community poverty (≥20% living below the federal poverty level) was associated with ...
    Chikoko mud is abundant in the mangrove swamps of the Niger Delta area of Nigeria. Its utilization in concrete production is traceable to its pozzolanic properties. In this paper, a regression model is developed to predict and optimize... more
    Chikoko mud is abundant in the mangrove swamps of the Niger Delta area of Nigeria. Its utilization in concrete production is traceable to its pozzolanic properties. In this paper, a regression model is developed to predict and optimize the flexural strength of chikoko pozzolana blended cement concrete using Osadebe’s regression function. The results obtained from the derived regression model are very close to those obtained from experiment. The model was tested for adequacy using a Fisher test at 5% level of significance and was found to be adequate. A computer program coded in basic language was used to select the mix ratios that would optimize the flexural strength of chikoko pozzolana blended cement concrete. The computer program is user-friendly and can be used to select the mix ratios corresponding to a desired strength value with reasonable accuracy and without waste of time. http://dx.doi.org/10.4314/njt.v36i3.8
    The study aims at comparing two methods of concrete mix design; The British Department of Environment Method and The American Concrete Institute Method, using the crushed and uncrushed coarse aggregates at various target strengths. A... more
    The study aims at comparing two methods of concrete mix design; The British Department of Environment Method and The American Concrete Institute Method, using the crushed and uncrushed coarse aggregates at various target strengths. A total of Forty-Five cubes were produced. Fifteen concrete cubes were produced with crushed aggregates (Granite) using the DOE method. Another fifteen cubes were produced with uncrushed coarse aggregates (Gravel) using the DOE method, while the remaining fifteen concrete cubes were produced with crushed aggregates using the ACI method. Each of these cube were produced at different mix strength M20, M30 and M50, according to IS 456:2000 and tested at different curing days; 7days, 14days and 24days respectively. The compressive strength values were determined at ages 7, 14 and 28 days curing periods respectively. Results obtained showed that the uncrushed aggregates gave a higher 28days compressive strength compared to that obtained from the crushed aggreg...
    Background: Diabetes is a metabolic disorder with a highly complex, multifaceted and intricate etiologies and thus may require management options that proffers multimodal mechanism of action. This present study evaluated the antidiabetic... more
    Background: Diabetes is a metabolic disorder with a highly complex, multifaceted and intricate etiologies and thus may require management options that proffers multimodal mechanism of action. This present study evaluated the antidiabetic and antioxidant potential of the methanolic extract/fractions of leaves of Ocimum canum. Methods: The antidiabetic potential was evaluated and using STZ-induced diabetic Wistar rat model (in vivo) and inhibition of α-amylase and α-glucosidase activity (in vitro). Antioxidant activity was assessed in vitro by free radical scavenging and reducing power assays and in vivo via monitoring SOD and CAT activities; GSH and MDA levels. Results: The total phenolic content (221.0±3.0 mg catechol/g of sample) and tannins (146.0±4.0 mg tannic acid/g of sample) of the crude extract; and flavonoid of the aqueous-methanol fraction (216.0.0±1.0 mg of rutin/g of sample) were found to be significantly higher relative to others. The crude extract and the aqueous-methan...
    In the earlier paper, a simple probabilistic model was formulated to predict the reliability of concrete in a structure during construction, a case study of laboratory block for College of Continuing Education, University of Port... more
    In the earlier paper, a simple probabilistic model was formulated to predict the reliability of concrete in a structure during construction, a case study of laboratory block for College of Continuing Education, University of Port Harcourt, Rivers State. In this paper, the reliability of the structure is predicted using decision theory based criteria as a tool. The net probability of failure of the structure after assessment was 1.4898E -3 which exceeded the target value of probability of failure of 3.931E -6 for slabs, 4.78E -7 for beams in  exure, 1.591E -4 for beams in shear and 4.8E -5 for columns subjected to both dead and live-load combination.[1] Showing that the structure is not safe and can result in uncommon accidents to persons and damage to properties on collapse. Keywords: probabilistic model, decision theory based criteria, target value, uncommon accidents, collapse
    In this paper, a mathematical model is formulated f or the prediction of optimum mortar joint thickness in brickmortar couplet. The brick-mortar couplet is assume d to be sandwiched between two mortar joints and lo aded in compression.... more
    In this paper, a mathematical model is formulated f or the prediction of optimum mortar joint thickness in brickmortar couplet. The brick-mortar couplet is assume d to be sandwiched between two mortar joints and lo aded in compression. The predicted curves agreed favorably with those of the experimental values. It was sho wn that the optimum mortar thickness for both the predicted and experimental curves was 10mm. The correlation coe fficient between the experimental and predicted values was h(0.945) showing the efficacy of the formulated model in the analysis and design of brick-mortar couplet under c ompressive loading.
    In this paper, the reliability analysis of a solid timber column subjected to both axial and lateral loading in accordance with the design requirements of Eurocode 5 using interaction formula is reported. The First Order Reliability... more
    In this paper, the reliability analysis of a solid timber column subjected to both axial and lateral loading in accordance with the design requirements of Eurocode 5 using interaction formula is reported. The First Order Reliability Method (FORM) which was written in FORTRAN language was invoked in the estimation of reliability levels. The effect of changing load ratios as well as the slenderness ratio of the timber column was examined. The results obtained showed that changing load ratios has effects on the reliability of timber columns. The obtained results also showed that the reliability of such a column can be improved by choosing adequate suitable dimensions in order to have a low slenderness ratio.
    Background The impact of social determinants of health on children with polyarticular juvenile idiopathic arthritis (pJIA) is poorly understood. Prompt initiation of treatment for pJIA is important to prevent disease morbidity; however, a... more
    Background The impact of social determinants of health on children with polyarticular juvenile idiopathic arthritis (pJIA) is poorly understood. Prompt initiation of treatment for pJIA is important to prevent disease morbidity; however, a potential barrier to early treatment of pJIAs is delayed presentation to a pediatric rheumatologist. We examined the impact of community poverty level, a key social determinant of health, on time from patient reported symptom onset to first pediatric rheumatology visit among pJIA patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. Methods This is a cohort study of pJIA patients in the CARRA registry who lived in the United States from July 2015–February 2020. The primary exposure was community poverty level derived by geocoding patient addresses. The primary outcome was time to first rheumatology appointment. Kaplan-Meier analysis was performed to analyze time to first rheumatologist visit, stratified b...
    Urban flooding has become a monumental yearly disaster in many of the world’s cities and Gombe town in particular. This paper focused on some hydro-geomorphological characteristics that influence flooding in Gombe town. Statistical... more
    Urban flooding has become a monumental yearly disaster in many of the world’s cities and Gombe town in particular. This paper focused on some hydro-geomorphological characteristics that influence flooding in Gombe town. Statistical methods and geographic information techniques were used for the assessment. The result revealed that the highest API of 166.62 mm occurred on the 5/9/2014. The rainfall amount was 92.5mm for a duration 48 minutes, average rainfall intensity was 115.63, stage height (1.42m), average flow velocity (0.98m/s), and instantaneous discharge of 9.47m3 /s. This corresponds with the flood disaster that occurred in Gombe town on the same date (5/9/2014). On the other hand, the least API of 18.12 mm occurred on the 18/6/2014. The rainfall amount was 1.2mm for 62 minutes, average rainfall intensity was 1.16, stage height (0.30m), average flow velocity (0.24m/s), and instantaneous discharge of 0.49m3 /s. findings also showed that very steep slope covered 2.4537km2 (1.7...
    Down syndrome–associated arthritis (DA) is underrecognized, and current therapies used for juvenile idiopathic arthritis (JIA) appear to be poorly tolerated and less effective in patients with DA. The objective of this study was to... more
    Down syndrome–associated arthritis (DA) is underrecognized, and current therapies used for juvenile idiopathic arthritis (JIA) appear to be poorly tolerated and less effective in patients with DA. The objective of this study was to characterize clinical manifestations and therapeutic preferences in DA compared to JIA, using the new Childhood Arthritis and Rheumatology Research Alliance (nCARRA) registry.
    An analytical study was carried out to investigate the structural properties of palmnut fibre reinforced cement-based composites. Explicit expressions were derived for the flexural, compressive and elongation behavior of composites using... more
    An analytical study was carried out to investigate the structural properties of palmnut fibre reinforced cement-based composites. Explicit expressions were derived for the flexural, compressive and elongation behavior of composites using a two-phase constitutive model and verified using results obtained from literature. The predicated and measured values were found to agree favourably. Both the predicted and measured composite specimens showed increasing flexural strength up to the optimum fibre volume fraction while the compressive strength decreases with increase in fibre volume fraction. The correlation coefficients were high showing the effectiveness of the two-phase constitutive models in the analysis and design of palmnut fibre-reinforced cement composites.
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    The cutting resistance of sugar cane was determined by use of a new-type manually operated agricultural test machine using two sugar cane varieties Noble (A) and Indigenous canes (B). The moisture content of the sugar cane used in the... more
    The cutting resistance of sugar cane was determined by use of a new-type manually operated agricultural test machine using two sugar cane varieties Noble (A) and Indigenous canes (B). The moisture content of the sugar cane used in the study was determined by the oven dry method. The cutting force and power required were determined using the test machine. The results showed that the average liquid content for variety A and B were 80% and 75% respectively. The cutting resistant for variety A and B were 3.93 kN/m and 5.5 kN/m respectively. The average applied cutting force of 147.3 N for variety B was higher than 130.7 N for variety A. The average power requirement for cutting variety A and B were 8.28W and 9.89W respectively. An analysis of the results using ANOVA at p ≤ 0.05 showed that there was no significant difference in the measured parameters for the two varieties of sugar cane used in this study. The results obtained will be useful in the design and manufacturing process of cu...
    The two studied, 34 and 52 km long parallel profiles are located over a gradually deepening sedimentary basin (Fig. 1). Northward these profiles terminale near the Raba Line which separates the East Alpian tectonic unit from that of the... more
    The two studied, 34 and 52 km long parallel profiles are located over a gradually deepening sedimentary basin (Fig. 1). Northward these profiles terminale near the Raba Line which separates the East Alpian tectonic unit from that of the Transdanubian Central Range and the profiles are nearly perpendicular to its strike direction. Magnetotelluric profiles measured earlier over the latter tectonic unit have revealed a conductive zone within the crust.
    Limited information is available on the contemporary and potentially changing trends in the incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction (STEMI). We queried the 2003-2010... more
    Limited information is available on the contemporary and potentially changing trends in the incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction (STEMI). We queried the 2003-2010 Nationwide Inpatient Sample databases to identify all patients ≥ 40 years of age with STEMI and cardiogenic shock. Overall and age-, sex-, and race/ethnicity-specific trends in incidence of cardiogenic shock, early mechanical revascularization, and intra-aortic balloon pump use, and inhospital mortality were analyzed. From 2003 to 2010, among 1 990 486 patients aged ≥ 40 years with STEMI, 157 892 (7.9%) had cardiogenic shock. The overall incidence rate of cardiogenic shock in patients with STEMI increased from 6.5% in 2003 to 10.1% in 2010 (P(trend)<0.001). There was an increase in early mechanical revascularization (30.4% to 50.7%,…
    ... However, T-DNA from A. vilis strain CG49 transferred to V. riparia cells at a lower rate than to V. vinifera cells, as determined by evaluation of uìdA gene (GUS) expression. ... After 3 days, the in vivo GUS (^-glucuroni-dase) assay... more
    ... However, T-DNA from A. vilis strain CG49 transferred to V. riparia cells at a lower rate than to V. vinifera cells, as determined by evaluation of uìdA gene (GUS) expression. ... After 3 days, the in vivo GUS (^-glucuroni-dase) assay (1,7) was performed. ...
    Our understanding of the biological pathogenesis of systemic lupus erythematosus (SLE) is rapidly expanding. Although biologic research is vital, studies that address the importance of socioeconomic factors that contribute to the... more
    Our understanding of the biological pathogenesis of systemic lupus erythematosus (SLE) is rapidly expanding. Although biologic research is vital, studies that address the importance of socioeconomic factors that contribute to the causation of the outcome of SLE are necessary to understand the full scope of the disease.Studies of social factors in SLE usually include ethnicity, gender and socioeconomic status (SES) as categorical variables. One hypothesis is that these variables exert their effect through a biologic or genetic factor. However, there is growing evidence to suggest a more direct psychological or sociological impact of these variables on disease. Although in research studies it may be difficult to tease out the biological and sociological impacts of these variables, the eventual understanding of these diverse roles will help in the design of eventual therapeutic interventions.