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2011, Journal of Sol-Gel Science and Technology
ABSTRACTObjectiveTo determine the impact of a digital sepsis alert on patient outcomes in a UK multi-site hospital network.MethodsA natural experiment utlising the phased introduction of a digital sepsis alert into a multi-site hospital network. Sepsis alerts were either visible to clinicans (the ‘intervention’ group) or running silently and not visible (the control group). Inverse probability of treatment weighted multivariable logistic regression was used to estimate the effect of the intervention on patient outcomes.Outcomes: In-hospital 30-day mortality (all inpatients), prolonged hospital stay (≥7 days) and timely antibiotics (≤60 minutes of the alert) for patients who alerted in the Emergency Department.ResultsThe introduction of the alert was associated with lower odds of death (OR:0.76; 95%CI:(0.70, 0.84) n=21,183); lower odds of prolonged hospital stay ≥7 days (OR:0.93; 95%CI:(0.88, 0.99) n=9988); and in patients who required antibiotics, an increased odds of receiving time...
Australian Journal of Education
Digital Natives? New and Old Media and Children's Outcomes2011 •
The current generation of young children has been described as ‘digital natives’, having been born into a ubiquitous digital media environment. They are envisaged as educationally independent of the guided interaction provided by ‘digital immigrants’: parents and teachers. This article uses data from the Longitudinal Study of Australian Children (LSAC) to study the development of vocabulary and traditional literacy in children aged from 0 to 8 years; their access to digital devices; parental mediation practices; children's use of digital devices as recorded in time-diaries; and, finally, the association between patterns of media use and family contexts on children's learning. The analysis shows the importance of the parental context in framing media use for acquiring vocabulary, and suggests that computer (but not games) use is associated with more developed language skills. Independently of these factors, raw exposure to television is not harmful to learning.
We have developed Digital Spatial Profiling (DSP), a non-destructive method for high-plex spatial profiling of proteins and RNA, using oligonucleotide detection technologies with unlimited multiplexing capability. The key breakthroughs underlying DSP are threefold: (1) multiplexed readout of proteins/RNA using oligo-tags; (2) oligo-tags attached to affinity reagents (antibodies/RNA probes) through a photocleavable (PC) linker; (3) photocleaving light projected onto the tissue sample to release PC-oligos in any spatial pattern. Here we show precise analyte reproducibility, validation, and cellular resolution using DSP. We also demonstrate biological proof-of-concept using lymphoid, colorectal tumor, and autoimmune tissue as models to profile immune cell populations, stroma, and cancer cells to identify factors specific for the diseased microenvironment. DSP utilizes the unlimited multiplexing capability of modern genomic approaches, while simultaneously providing spatial context of p...
SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging
Dental education at the crossroads2000 •
2007 •
isara solutions
EBIT -EPS Analysis of Shriram Properties LtdCompanion to Aesthetics
Twentieth-century Anglo-American Analytic Aesthetics2009 •
2014 •
L'architettura delle città. the journal of the Scientific Society Ludovico Quaroni
Historical analysis of a Roman urban center. Hispellum as a case study2024 •
2017 •
2024 •
Academia Revista Sobre Ensenanza Del Derecho De Buenos Aires
Vicisitudes de la reforma de la reforma curricular en la Facultad de Ciencias Jurídicas y Sociales de la Universidad de San Carlos de Guatemala2009 •
Asian journal of research in medical and pharmaceutical sciences
Evaluation of Stability and TLC Fingerprinting of the Artemether Component in Artemether-Lumefantrine Combination Suspension Formulations Available in Nigeria Pharmaceutical Market2023 •
Journal of Applied Psychology
Voluntary survey completion among team members: Implications of noncompliance and missing data for multilevel research2013 •