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1995, Schizophrenia Research
Brain Research
Electrical sensitization of the meso-limbic dopaminergic system in rats: a pathogenetic model for schizophrenia1993 •
Thalamus and Related Systems
Effects of acute amphetamine in the mediodorsal nucleus of the thalamus: possible relevance for psychiatric disorders Amphetamine administration alters thalamic activity2002 •
1995 •
Molecular Brain Research
Comparison of the effects of an ampakine with those of methamphetamine on aggregate neuronal activity in cortex versus striatum1997 •
The present study used in situ hybridization to c-fos mRNA to compare the effects of an 'ampakine' (a positive modulator of AMPA type glutamate receptors) with those of methamphetamine on the balance of aggregate neuronal activity in the cortex versus striatum. Methamphetamine (n = 11) induced a marked increase in c-fos mRNA in the dorsomedial quadrant of the striatum and a 21% smaller, but still reliable, increase in the ventrolateral quadrant. The drug also elevated c-fos mRNA levels in the ventral and medial segments of the orbitofrontal cortex but had no detectable effects in motor and somatosensory neocortices. The ampakine (n = 11) caused a near inverse pattern of changes; i.e. a sizable increase in somatosensory labeling and a significant decrease in striatal labeling with statistically insignificant effects in motor and orbitofrontal cortex. Within-rat cortical and striatal values were correlated in both the vehicle (n = 11) and ampakine groups, and appropriate comparisons established that the ampakine caused 27-55% increases in the ratio of cortical to striatal labeling. These results are in accord with the idea that facilitation of glutamatergic transmission has 'network level' effects that are opposite in nature to those resulting from enhanced dopaminergic transmission. The potential relevance of ampakines alone or in conjunction with dopamine antagonists for the treatment of schizophrenia is discussed.
European Journal of Neuroscience
Compartment-specific changes in striatal neuronal activity during expression of amphetamine sensitization are the result of drug hypersensitivity2002 •
Archives of General Psychiatry
Increased Synaptic Dopamine Function in Associative Regions of the Striatum in Schizophrenia2010 •
The Journal of Neuroscience : The Official Journal of the Society for Neuroscience
Repeated treatment with haloperidol and clozapine exerts differential effects on dye coupling between neurons in subregions of striatum and nucleus accumbens2014 •
Scottish Historical Review
Katherine Beaumont, Countess of Atholl, and the Second Scottish War of Independence (c. 1327–c. 1336)2023 •
2023 •
2012 •
2023 •
Early Childhood Education Journal
"Treat Them Like Human Beings": Black Children's Experiences with Racial Microaggressions in Early Childhood Education During COVID-192023 •
2013 •
Physical Review A
Nonadiabatic transition probabilities in the presence of strong dissipation at an avoided-level crossing point2002 •
The Journal of Thoracic and Cardiovascular Surgery
Outcome of aortic arch reconstruction in infants with coarctation: Importance of operative approach2016 •
2018 •
International journal of culture and religious studies
Matt 25:14-30: A Critical Look at the ‘Third Servant Syndrome’ in the Light of Theological Studies in Nigeria2023 •
Journal of Biotechnology
Mutational approach for enhancement of artemisinin in Artemisia annua2010 •
DergiPark (Istanbul University)
Türkiye’de Yayımlanan Eleştirel Pedagoji Araştırmaları Üzerine Bir Bibliyografik Çözümleme2023 •
Libyan journal of medical research
Development and validation of questionnaire regarding KAP survey on pulmonary and systemic TB2023 •
2019 •
The American journal of tropical medicine and hygiene
{"__content__"=>"Therapeutic Response to Dihydroartemisinin-Piperaquine for and Nine Years after Its Introduction in Southern Papua, Indonesia.", "i"=>[{"__content__"=>"P. falciparum"}, {"__content__"=>"P. vivax"}]}2018 •