Long covid: coding is caring

Journal of Clinical Medicine

↔This study aims to compare the characteristics, in-hospital data and rehabilitation needs between those who tested positive versus negative for COVID-19 during hospitalisation with suspected COVID-19. In this cross-sectional study, a convenience sample of adults admitted to Western Australian tertiary hospitals with suspected COVID-19 was recruited. Participants were grouped according to their polymerase chain reaction (PCR) test result into COVID-19 positive (COVID+) and COVID-19 negative (COVID−) groups. Between-group comparisons of characteristics of the participants and hospital admission data were performed. Sixty-five participants were included (38 COVID+ and 27 COVID−; 36 females [55%]). Participants in the COVID+ group had greater acute hospital length of stay (LOS) (median [25–75th percentile] 10 [5–21] vs. 3 [2–5] days; p < 0.05] and only those with COVID+ required mechanical ventilation (8 [21%] participants). Twenty-one percent of the COVID+ participants were dischar...

medRxiv (Cold Spring Harbor Laboratory), 2022

2021

SummaryObjectivesTo investigate the experience of people who continue to be unwell after acute COVID-19, often referred to as ‘long COVID’, both in terms of their symptoms and their interactions with healthcare.DesignWe conducted a mixed-methods analysis (quantitative and qualitative) of responses to a survey accessed through a UK online post-COVID support and information hub between April 2020 and December 2020 about people’s experiences after having acute COVID-19.ParticipantsOf 3290 respondents, 78% were female, median age range 45-54 years, 92.1% reported white ethnicity; 12.7% had been hospitalised. 494 respondents (16.5%) completed the survey between 4 and 8 weeks of the onset of their symptoms, 641 (21.4%) between 8 and 12 weeks and 1865 (62.1%) more than 12 weeks after.ResultsThe ongoing symptoms most frequently reported were; breathing problems (92.1%), fatigue (83.3%), muscle weakness or joint stiffness (50.6%), sleep disturbances (46.2%), problems with mental abilities (4...

BMJ Open, 2020

ObjectivesTo describe the characteristics and outcomes of hospitalised patients with COVID-19 from UK in the highest decile of health and gross regional products per capita.DesignProspective cohort study.SettingRecruited all adult inpatients with laboratory-confirmed COVID-19 symptoms admitted to a single Surrey centre between March and April 2020. Extensive demographic details were documented.Outcome measureCOVID-19 status of alive/dead and intensive care unit (ICU) status of yes/no.ParticipantsPatients with COVID-19 from Surrey centre UK (n=429).Results429 adult inpatients (mean age 70±18 years; men 56.4%) were included in this study, of whom, 19.1% required admission to ICU and 31.9% died. Adverse outcomes were associated with age (OR with each decade of years: 1.78, 95% CI 1.53 to 2.11, p<0.001 for mortality); male gender (OR=1.08, 95% CI 0.72 to 1.63, p=0.72, present in 70.7%, of admissions to ICU versus 53% of other cases, p=0.004); cardiac disease (OR=3.43, 95% CI 2.10 to ...

The Lancet Respiratory Medicine, 2021

Clinical Microbiology and Infection, 2020

Molecules are chemical structures composed of atoms, and in order to improve the understanding of the classical organic chemistry concepts it is necessary to have accessible mathematical models that contain all the important structural elements of a molecule. An interesting tool for organic chemistry is represented by the prediction of the number of π-bonds, σ-bonds, single, double and triple bonds for organic compounds based on their molecular formulas in order to solve different kinds of problems regarding the representation of molecules. In this manuscript we try to present a simple method comprised of multiple empirical equations for two important classes of organic molecules that can have a significant impact on their rapid calculation of chemical bonds. Therefore, our new mathematical model that will be presented enable an easy calculation of the number of π-bonds, σ-bonds, single, double and triple bonds for graphical representations of the molecular structures that corresponds to open chain alcohols and cycloamines using their molecular formulas.

INAC, 2022

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