CTI

From proactive detection of cyberattacks to the identification of key actors, analyzing contents of the Dark Web plays a significant role in deterring cybercrimes and understanding criminal minds. Researching in the Dark Web proved to be an essential step in fighting cybercrime, whether with a standalone investigation of the Dark Web solely or an integrated one that includes contents from the Surface Web and the Deep Web. In this review, we probe recent studies in the field of analyzing Dark Web content for Cyber Threat Intelligence (CTI), introducing a comprehensive analysis of their techniques, methods, tools, approaches, and results, and discussing their possible limitations. In this review, we demonstrate the significance of studying the contents of different platforms on the Dark Web, leading new researchers through state-of-the-art methodologies. Furthermore, we discuss the technical challenges, ethical considerations, and future directions in the domain.

Introducao: As incompatibilidades medicamentosas quando ocorrem sao consideradas erro de medicacao, e o produto resultante pode afetar a eficacia e a seguranca da terapia, sendo que conhecer seus fundamentos pode ajudar a prevenir sua ocorrencia diminuindo, assim, seus riscos. Objetivo: Identificar e quantificar as incompatibilidades fisico-quimicas entre medicamentos administrados atraves da via intravenosa em pacientes internados no Centro de Tratamento Intensivo (CTI) do Hospital de Clinicas de Porto Alegre (HCPA), observar a possibilidade de orientacoes farmaceuticas para a administracao dos medicamentos incompativeis. Metodologia: Estudo transversal, no qual foram avaliadas as prescricoes de Marco a Maio de 2010, a partir dos prontuarios eletronicos, verificando a ocorrencia de incompatibilidades medicamentosas entre as formas farmaceuticas intravenosas. Foi realizada uma intervencao farmaceutica por meio de orientacoes quanto a administracao dos medicamentos identificados como...

We investigated the long-term efficacy of cryo ablation for treatment of atrial flutter.To our knowledge, no study has assessed the long-term efficacy of cryo ablation by assessing both symptom and conduction recurrence.A total of 45 consecutive patients with symptomatic atrial flutter were ablated with a 7-F, 6-mm-tip, quadripolar cryo catheter (Freezor Xtra, CryoCath Technologies Inc., Kirkland, Canada). Electrophysiologic studies (EPS) were performed with diagnostic catheters. Cryo ablation was at −75°C for 4 min, beginning at the inferior rim of the coronary sinus os and creating a posterior line to the Eustachian ridge. Safety, bi-directional isthmus block at intervention, and recurrence at three, six, and nine months post procedure were assessed.There were no adverse events reported. All patients were free of discomfort on cryo energy delivery. The acute success rate at intervention was 87%. Follow-up data from 39 acutely successful patients showed 27 (69%) without conduction recurrence on repeat EPS at three months, and none (0%) had symptom recurrence documented by Holter monitoring, electrocardiogram, and/or patient diary records at three, six, and nine months follow-up.Our experience with a new 7-F, 6-mm-tip, quadripolar cryo catheter yielded a fairly high success rate at intervention, an excellent safety profile, and a good chronic success rate in terms of symptom recurrence. However, further monitoring is necessary to determine whether all asymptomatic patients continue to remain free of symptoms, given the small pool of patients demonstrated to have conduction recurrence.