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      AgingCell SignalingMuscle PhysiologyCancer cachexia
Submitted by Prof. Anthony James MSc.(Clinical Herbology), DNM(C), ND(T), MD(AM), DOM(Acu), DPHC(h.c.), PhD(IM), PhD(Hospitallar Medicine h.c.), DMM, RAAP, UTTS, MSGR./CHEV., Ordained Native Monsignor Native Bishop, Eastern Orthodox... more
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    •   9  
      Native American StudiesThai StudiesIntegrative AyurvedaPalliative Medicine
Cachexia affects the majority of patients with advanced cancer. It leads to poor surgical and oncological outcomes, and negatively affects quality of life. It has long been reported that components of the host immune system, including... more
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    •   4  
      MacrophagesCancer cachexiaImmunotherapyInterleukins
Cancer cachexia remains a challenging clinical problem with complex pathophysiology and unreliable diagnostic tools. A blood test to detect this metabolic derangement would aid in early treatment of these patients. A 1H NMR-based... more
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    •   13  
      Analytical ChemistryStatistical AnalysisMetabolomicsCancer cachexia
Background Cachexia is a syndrome which is a common feature in more than 80% of patients with advanced cancer and globally accounts for over two million deaths per annum. At present there are no standard treatment guidelines for cancer... more
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    •   5  
      Qualitative ResearchCancer cachexiaSymbolic InteractionismMulti professional care
There is a paucity of research studies in palliative care with less than 1% of clinical trials being relevant to the hospice and palliative care setting.1 Difficulties in conducting studies with this client group such as recruitment,... more
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    •   8  
      NursingPalliative CareCancerHospice & Palliative Care Nursing
Cachexia is among the most debilitating and life-threatening aspects of cancer, especially in the palliative care setting. It represents a metabolic syndrome affecting essential functional circuits involved in the regulation of... more
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    •   6  
      Palliative CareCancer cachexiaHospice and Palliative careCachexia
Approximately half of all cancer patients present with cachexia, a condition in which disease-associated metabolic changes lead to a severe loss of skeletal muscle mass. Working toward an integrated and mechanistic view of cancer... more
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    •   18  
      OncologySkeletal muscle biologyCancerNuclear Magnetic Resonance
Backgrounds: There has been no prospective study to investigate the effect of nutritional support for advanced cancer patients in inpatient hospices. Therefore, we conducted a prospective observational study to explore the feasibility of... more
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      Cancer cachexiaFeasibilityNutritional SupportAdvanced cancer patient
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    •   18  
      ImmunologyCancerSurvival AnalysisCancer Biology
Background The prevalence of nutritional derangements in patients with cancer is high. This survey assessed patients' awareness of cancer‐related nutritional issues and evaluated how important they perceive the impact of nutrition on... more
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      Nutrition and DieteticsNutritionCancerCancer cachexia
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    •   18  
      ImmunologyCancerSurvival AnalysisCancer Biology
The enzyme fatty acid amide hydrolase (FAAH) catalyzes the in vivo degradation of the endocannabinoid anandamide, thus controlling its action at receptors. A novel FAAH inhibitor, AM3506, normalizes the elevated blood pressure and cardiac... more
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    •   14  
      BiochemistryObesityDiabetesFood and Nutrition