Double Blind
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Recent papers in Double Blind
Background: The double-blind, placebo-controlled food challenge (DBPCFC) is the “gold standard” for diagnosis of food hypersensitivity. Skin prick tests and RASTs are sensitive indicators of food-specific IgE antibodies but poor... more
Psoriatic arthritis (PsA), an inflammatory arthritis associated with psoriasis usually seronegative for rheumatoid factor, has emerged as a more common and severe disease than previously appreciated. The disease is multifaceted. Thus the... more
Background: Evidence-based pharmacological treatment options for patients with persistent inguinal postherniorrhaphy pain are lacking. Methods: Twenty-one male patients, with severe, unilateral, persistent inguinal postherniorrhaphy pain,... more
Objective In spite of interventions being put in place to reduce the burden of maternal anaemia and malaria in Ghana, these problems continue to impact negatively on pregnancy outcomes. It is unclear whether there are some other factors... more
To date, antidepressant drugs show limited efficacy, leaving a large number of patients experiencing severe and persistent symptoms of major depression. Previous open-label clinical trials have reported significant sustained improvements... more
Elevated blood pressure, particularly systolic blood pressure, increases the risk of cardiovascular and renal complications in patients with diabetes. Current national guidelines set the blood pressure goal for those with diabetes at <... more
El uso de placebos y diseños a doble ciego ha cumplido un papel crucial en la investigación clínica en Medicina. Su aplicación a la investigación de resultados en psicoterapia ha sido controversial. Muchos autores niegan la posibilidad de... more
Technological advancements has offered many solutions to the important current issues such as the growing numbers of run away children, wandering Alzheimer’s patients and lost pets in the society, yet most branches of current technologies... more
BackgroundLithium and quetiapine are considered standard maintenance agents for bipolar disorder yet it is unclear how their efficacy compares with each other.AimsTo investigate the differential effect of lithium and quetiapine on... more
Evaluate the efficacy and safety/tolerability of cryoneurolysis for reduction of pain and symptoms associated with knee osteoarthritis (OA). Randomized, double-blind, sham-controlled, multicenter trial with a 6-month follow-up in patients... more