Glomerular Basement Membrane
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Recent papers in Glomerular Basement Membrane
RPS19 (ribosomal protein S19), a component of the 40S small ribosomal subunit, has recently been identified to bind the pro-inflammatory cytokine macrophage MIF (migration inhibitory factor). In vitro experiments identify RPS19 as the... more
Background. In small vessel vasculitis and its renal- limited form, idiopathic crescentic glomerulonephritis, renal damage is characterized by pauci-immune necro- tizing crescentic glomerulonephritis (CGN) without histological evidence of... more
Vascular endothelial growth factor, which is critical for blood vessel formation, is regulated by hypoxia inducible transcription factors (HIFs). A component of the E3 ubiquitin ligase complex, von Hippel-Lindau (VHL) facilitates... more
Summary Mac-1 ( a m b 2 ), a leukocyte adhesion receptor, has been shown in vitro to functionally interact with Fc g receptors to facilitate immune complex (IC)-stimulated polymorphonuclear neutro- phil (PMN) functions. To investigate the... more
An association between low nephron number and subsequent development of hypertension in later life has been demonstrated. The underlying pathomechanisms are unknown, but glomerular and postglomerular changes have been discussed. We... more
Immunoglobulin A nephropathy (IgAN) is associated with mucosal IgA defect. Probiotics regulate specific and innate immunity. We evaluated the effect of Saccharomyces boulardii on experimental IgAN in mice. Four groups of BALB/c mice... more
The glomerular filtration barrier prevents large serum proteins from being lost into the urine. It is not known, however, why the filter does not routinely clog with large proteins that enter the glomerular basement membrane (GBM). Here,... more
Intrauterine growth restriction (IUGR) can reduce glomerutar number and increase blood pressure in rats. The aim of this study was to assess the effects of maternal undernutrition during late gestation on-glomerutar ultrastructure in... more
For the purpose of studying renal side effects induced by anticancer drugs, we inspected glomerular damage as well as tubular damage of patients with anticancer chemotherapy. Thirty patients medicated with anticancer drugs, which are... more