Bridging the Gap: Integrating 3D Bioprinting and Microfluidics for Advanced Multi-Organ Models in Biomedical Research
Abstract
:1. Introduction
2. The Promise of 3D Bioprinting
3. Main Limitations of 3D Bioprinting Technology
4. Microfluidic Lab-on-Chip Systems
5. Main Limitations of Microfluidic Lab-on-Chip Systems
6. Integration of 3D Bioprinting and Microfluidics
6.1. Advantages of Integration
6.2. Principles and Underlying Mechanisms
6.3. Examples of Applications
6.4. Mechanistic Insights
7. Reducing Animal Models in Research
7.1. Scientific Limitations
7.2. Ethical Considerations
8. Challenges and Future Directions
8.1. Technical and Practical Challenges in the Integration of Technologies
8.2. Potential Future Developments and Innovations
8.3. Long-Term Impact on Biomedical Research and Clinical Applications
9. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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De Spirito, M.; Palmieri, V.; Perini, G.; Papi, M. Bridging the Gap: Integrating 3D Bioprinting and Microfluidics for Advanced Multi-Organ Models in Biomedical Research. Bioengineering 2024, 11, 664. https://doi.org/10.3390/bioengineering11070664
De Spirito M, Palmieri V, Perini G, Papi M. Bridging the Gap: Integrating 3D Bioprinting and Microfluidics for Advanced Multi-Organ Models in Biomedical Research. Bioengineering. 2024; 11(7):664. https://doi.org/10.3390/bioengineering11070664
Chicago/Turabian StyleDe Spirito, Marco, Valentina Palmieri, Giordano Perini, and Massimiliano Papi. 2024. "Bridging the Gap: Integrating 3D Bioprinting and Microfluidics for Advanced Multi-Organ Models in Biomedical Research" Bioengineering 11, no. 7: 664. https://doi.org/10.3390/bioengineering11070664