Extended Data Figure 4: Comparison of GO enrichment of orthologous transcription-factor pairs. | Nature

Extended Data Figure 4: Comparison of GO enrichment of orthologous transcription-factor pairs.

From: Comparative analysis of regulatory information and circuits across distant species

Extended Data Figure 4

A comparison of GO enrichment of orthologous transcription-factor pairs for all contexts in human versus worm (a), human versus fly (b), and worm versus fly (c) is shown. Red boxes indicate level of similar GO enrichment. ‘Plus’ signs mark orthologous transcription-factor pairs with white ‘pluses’ indicating the most significant enrichment for an orthologue pair. d, Orthologous factors are more enriched for matching GO terms than non-orthologous factors.

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