Extended Data Figure 8: GDF15 and GLP1 activate independent pathways. | Nature

Extended Data Figure 8: GDF15 and GLP1 activate independent pathways.

From: Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15

Extended Data Figure 8

a, Body weight reduction after an injection of recombinant Fc–GDF15 or vehicle in wild-type (Glp1r+/+) or knockout (Glp1r−/−) mice. n = 6 animals. b, Body weight reduction after daily injections of GLP1 (Victoza) in wild-type (Gfral+/+) or knockout (Gfral−/−) mice. n = 9 animals per group. All data are mean ± s.e.m.

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