second period
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The second period of datataking at the Large Hadron Collider (LHC) has provided a large dataset of proton–proton collisions that is unprecedented in terms of its centre-of-mass energy of 13 TeV and integrated luminosity of almost 140 fb[Formula: see text]. These data constitute a formidable laboratory for the search for new particles predicted by models of supersymmetry. The analysis activity is still ongoing, but a host of results on supersymmetry had already been released by the general purpose LHC experiments ATLAS and CMS. In this paper, we provide a map into this remarkable body of research, which spans a multitude of experimental signatures and phenomenological scenarios. In the absence of conclusive evidence for the production of supersymmetric particles we discuss the constraints obtained in the context of various models. We finish with a short outlook on the new opportunities for the next runs that will be provided by the upgrade of detectors and accelerator.

Background: Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide. With the emergence of penicillin-resistant S. pneumoniae (PRSP), treatment has become challenging. The Clinical and Laboratory Standards Institute (CLSI) in 2008 revised its guidelines for S. pneumoniae and recommended separate penicillin breakpoints for meningeal and non-meningeal strains. Similar to penicillin’s, resistance to other classes of antibiotics has emerged globally. Objective: The objective of this study is to determine the trend of resistance to antimicrobials in S. pneumoniae infections and the impact of new CLSI guidelines on penicillin susceptibility among meningeal isolates. Methodology: Twenty-four years (1993-2016) data from S. pneumoniae isolates and their antimicrobial susceptibility was retrieved from the computerized database. Data was divided into two groups for analysis, pre-2008 and post 2008. Results: Penicillin resistance remained unchanged in non-meningeal isolates during both study periods. A significant rise in penicillin resistance in meningeal isolates was observed in the second period 2008-2016 (2.9% vs 36.2%). High resistance rates were observed for co-trimoxazole, tetracycline and erythromycin. Increased trend of multi-drug resistant (MDR) strains were also noted, from 11% in 1999 to 36% in 2016.  Conclusion: The emergence of MDR strains is evident from our dataset. It seems like the rise in PRSP in meningeal isolates is due to revised CLSI guidelines. Overall low resistance to penicillin in non-meningeal isolates and no resistance to ceftriaxone is encouraging and will assist in drafting local guidelines. Cautious use of antimicrobials are essential to reduce further emergence of antimicrobial resistance in indigenous isolates.  

Fresh agricultural produce is almost the staple food and necessity of people's daily diet all over the world. However, natural perishability and freshness affect the demand for fresh agricultural produce. Due to the change of freshness, the retailer has to adopt a multi-period dynamic pricing strategy to deal with unsold products. The research object of this paper is the retailer's two-echelon supply chain of fresh agricultural produce, and the aim is to achieve the optimal two-period coordination and ordering through options and wholesale contracts in the supply chain. In the case of two-period pricing, we find that the optimal wholesale order quantity increases with the decline of the price in the first period and tends to be stable with the decline of the price in the second period. In contrast, the price change in the first period has a greater impact on the retailer's optimal order quantity. The profits of both the retailer and the supplier increase significantly with the increase of the price in the first period, while the impact of the change of the price in the second period is not obvious. Meanwhile, decentralized decision-making can only be coordinated in the supply chain through the original option contract at the first-period price. In the second period, the cost-sharing contract is introduced to coordinate the supply chain, increase orders, and increase the profits of both the retailer and the supplier. These findings are of great significance for both the retailer and the supplier in the multi-period dynamic pricing of fresh produce under the option contract.

Joko Widodo (Jokowi) is the first Indonesian Democratic President elected by the peripheral people and not the elite. Jokowi is the only Indonesian President that is not the leader of any political party. Therefore, the President was faced with the issues of power consolidation in the initial administrative years. Some professional elites failed the President because they assumed a possible overthrown. During the presidential election in 2019 with Prabowo Subianto, Jokowi took K. H. Ma'ruf Amien as a vice presidential candidate and was attacked by China and the Indonesian Communist Party (ICP/PKI). However, Jokowi was re-elected for the second period (2019-2024) due to his close relationship with Indonesians, which is different from other presidents.   Received: 23 August 2021 / Accepted: 24 November 2021 / Published: 3 January 2022

 Fractal dimension of the chaotic attractor for earthquake sequence in Nurek dam based on 22.000 earthquakes detected during the period 1976-87 has been studied for this total period of observations as well as for the period from December 1977 to December 1987. The second period excluded increased seismic activity during second stage of filling the reservoir. Large fractal dimensions of the chaotic at tractor of 8.3 and 7.3 were found for the respective period which suggests the complexity of earthquake .dynamics in this region as compared to Koyna reservoir.  

95 years ago, namely on October 12, 1926, through the efforts of 27 founders, including professors G.I. Turner, A.L. Polenov, R.R. Vreden and G.A. Albrecht, the first scientific society of orthopedic surgeons of Leningrad and the Leningrad region was created in our country, which continues to be an indispensable platform for the training of scientific personnel, the exchange of practical experience and research results directed by authoritative figures of domestic traumatology and orthopedics, the successors of the Leningrad school of orthopedic surgeons. The article summarizes the results of the societys work during four periods of its activity: the first period of formation (19261933), the second period work in the pre-war, war and post-war years (19341950), the third period the intensive development of traumatology and orthopedics (19501990) and the fourth period the modern rapid development of the specialty (since 1990). The main aim of the current activity and new areas of work are formulated.

В статье рассматривается творчество ленинградско-петербургского художника Александра Николаевича Рычкова-Галактионова (р. 1948), живописца и графика, выпускника Института имени И.Е. Репина Российской академии художеств (1973). Особенностью его творческого пути стало обоснование им в 1990 году собственного творческого метода, названного «энергетизм», и изобразительной манеры «еxtantion». Его творчество условно делится на три периода, первый из которых — нащупывание своего авторского «я» (1970–1980-е годы). Второй период связан со временем исторической эпохи «перестройки», некоторые стороны которой художник стремился передать метафизическим изобразительным языком, отходя от прежней реалистической живописной манеры. Этот период может быть назван переходным к следующему, полуфигуративному этапу творчества, на котором художник окончательно формулирует свое творческое кредо. The article examines the work of the Leningrad-Petersburg artist Alexander Rychkov-Galaktionov (b. 1948), a painter and graphic artist, a native of the I.E. Repin Institute of the Russian Academy of Arts (1973). A feature of his creative path was the substantiation by him in 1990 of his own creative method, called “energetism”, and the pictorial manner of “extantion”. His work is conventionally divided into three periods, the first of which is the groping of his author's self (1970s – 1980s). The second period is associated with the time of the historical era of "perestroika", some aspects of which the artist strove to convey in metaphysical pictorial language, departing from the previous realistic painting manner. This period can be called a transitional to the next, semi-figurative stage of creativity, at which the artist finally formulates his creative credo.

Introduction: Some of the practices in medicine are carried out of habit without proven benefits. This is the case of premature babies from 31 to 34 weeks of gestation who are always given parenteral fluids, even though this practice has been associated with an increase incidence of infection. In 2017, we started a protocol of parenteral fluid restriction. To administer nutrition/fluids, we used oral fluids by suction if this was possible or otherwise by oral/nasogastric tube at volumes of 15-20 mL intake every 3 hours, with 5 mL increments every 12-24 hours until 200 mL/K/day was achieved, always using breast milk when possible.Material and methods: The present study sought to compare cases before and after this new policy. For this work, we review all premature babies between 31-34 weeks of gestation discharged home in two periods of time, the first from 01/01/2012 to 12/31/2017 and the second from 01/01/2018 to 08/31/2021. The number of cases with and without parenteral fluids (PF), the incidence of infection, the weight at admission and discharge, and the fall in the weight Z score between birth and discharge were compared. Both the anthropometric and outcome variables were compared using the different statistical methods according to each variable.Results: 725 cases were found with the described characteristics. The groups before and after the intervention did not show significant differences in their general demographic characteristics. A lower use of PF was observed in the second period from 348 cases (79%) to 70 (24%), p <0.001 and fewer days of use (4.1 days/case vs 1.3, p <0.0001) of PF. The weight at discharge and the change in weight Z-score were the same in both groups. Infections went from three cases to zero but it was not statistically significant. There were no complications due to less use of PF.Discussion: This study showed that the use of PF is not associated with significant changes in outcomes of interest, which reinforces that its use does not generate any benefit for the patient. Larger number of cases is required to detect differences in low incidence events such as infections.

In the article, the periodization of the formation and development of partnership pedagogy has been based on socio-pedagogical prerequisites, clarifying the contribution of prominent philosophers, educator-innovators in the development of theoretical, methodological, and technological aspects of partnership pedagogy. The author divides the formation and development of the pedagogy of partnership into two periods: the preparatory and the development of the ideas of partnership pedagogy.The chronological framework of the preparatory period – from antiquity (V century BC) to the 80s of the XX century has been determined. There are two stages within the preparatory period: the first stage – from antiquity (V century BC) to the 50s of the twentieth century, the second stage – the 50–80s of the twentieth century. It has been established that within the first stage, the studied phenomenon is not the object of purposeful holistic study it appeals to it are spontaneous and unsystematic, knowledge about it is scanty and contradictory. The second stage of the preparatory period (the '50s – the mid-'80s of the twentieth century) has been characterized by a systematic study of certain aspects of the problem, the emergence of theories and concepts of cooperation pedagogy, which in the future form the basis of partnership pedagogy, help determine its formation and development.The peculiarities of the second period of the partnership pedagogy development (from 1986 to the present) have been clarified. Two stages of this period are distinguished by the author: the first – from 1986 to 2016, the second – from 2016 to the present. The first stage begins with the signing by the teachers-innovators of the Manifesto “Pedagogy of Cooperation” (1986) and has been characterized by a thorough scientific study, design of ways and means of development of the cooperation pedagogy. Since 2016, when the Concept of the New Ukrainian School has been adopted, the second stage of the second period of formation of partnership pedagogy begins. The concept of “partnership pedagogy” has been transferred from the world view to the normative plane; research is actively carried out, and ideas of partnership pedagogy are developed. Keywords: partnership pedagogy; cooperation pedagogy; philosophical thought; humanism; teachers-innovators; New Ukrainian School; periodization; formation and development.

Objective Mortality rates of pregnant and postpartum women grew in the second COVID-19 pandemic year. Our objective is to understand this phenomenon to avoid further deaths. Methods We collected data from SIVEP-Gripe, a nationwide Brazilian database containing surveillance data on all severe acute respiratory syndrome caused by COVID-19, between the first notified case (February 2020) until the 17th epidemiological week of 2021. We stratified patients into maternal women (which includes pregnant and postpartum women), non-maternal women and men and divided them by time of diagnosis in two periods: first period (February to December 2020) and second period (the first 17 epidemiological weeks of 2021 before pregnant and postpartum women were vaccinated). Results During the second period, all patients had higher risk of presenting severe COVID-19 cases, but the maternal population was at a higher risk of death (OR of 2.60 CI 95%: 2.28–2.97)–almost double the risk of the two other groups. Maternal women also had a higher risk of needing intensive care, intubation and of presenting desaturation in the second period. Importantly, maternal women presented fewer comorbidities than other patient groups, suggesting that pregnancy and postpartum can be an important risk factor associated with severe COVID-19. Conclusion Our results suggest that the Gama variant, which has been related to greater virulence, transmissibility and mortality rates leads to more severe cases of COVID-19 for pregnant and postpartum women.