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    Free T3

    Uploaded by

    Jason Roy Edward Nathan
    This document provides information about a test to measure free triiodothyronine (FT3) levels. FT3 is the fraction of the thyroid hormone T3 that is unbound to proteins and able to influence metabolism. Elevated FT3 levels are effective at detecting hyperthyroidism, while decreased levels are less useful for diagnosing hypothyroidism. FT3 measurements are not affected by thyroid binding protein levels and can be used along with free T4 and TSH assays to evaluate thyroid function. The test uses a patient's serum sample and an enhanced chemiluminescence method to measure FT3 levels.

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    © All Rights Reserved
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    Free T3

    Uploaded by

    Jason Roy Edward Nathan
    75 views1 page
    This document provides information about a test to measure free triiodothyronine (FT3) levels. FT3 is the fraction of the thyroid hormone T3 that is unbound to proteins and able to influence metabolism. Elevated FT3 levels are effective at detecting hyperthyroidism, while decreased levels are less useful for diagnosing hypothyroidism. FT3 measurements are not affected by thyroid binding protein levels and can be used along with free T4 and TSH assays to evaluate thyroid function. The test uses a patient's serum sample and an enhanced chemiluminescence method to measure FT3 levels.

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    describes about T3 hormone

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    Free_T3

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    This document provides information about a test to measure free triiodothyronine (FT3) levels. FT3 is the fraction of the thyroid hormone T3 that is unbound to proteins and able to influence metabolism. Elevated FT3 levels are effective at detecting hyperthyroidism, while decreased levels are less useful for diagnosing hypothyroidism. FT3 measurements are not affected by thyroid binding protein levels and can be used along with free T4 and TSH assays to evaluate thyroid function. The test uses a patient's serum sample and an enhanced chemiluminescence method to measure FT3 levels.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    75 views1 page

    Free T3

    Uploaded by

    Jason Roy Edward Nathan
    This document provides information about a test to measure free triiodothyronine (FT3) levels. FT3 is the fraction of the thyroid hormone T3 that is unbound to proteins and able to influence metabolism. Elevated FT3 levels are effective at detecting hyperthyroidism, while decreased levels are less useful for diagnosing hypothyroidism. FT3 measurements are not affected by thyroid binding protein levels and can be used along with free T4 and TSH assays to evaluate thyroid function. The test uses a patient's serum sample and an enhanced chemiluminescence method to measure FT3 levels.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    TEST: T3, FREE

    PRINCIPLE:
    The free fraction of the circulating triiodothyronine (T3) is considered to exert the main
    influence on metabolic control. In hyperthyroidism, FT3 concentrations are generally
    elevated and give efficient discrimination at the euthyroid/toxic borderline, providing an
    effective method for confirming hyperthyroidism and monitoring of its treatment. In
    hypothyroidism, FT3 concentrations tend to be lower, but the decrease is insufficient to
    give clear diagnostic information. FT3 concentrations are independent of the
    concentration of thyroid hormone-binding proteins, and may be measured in patients with
    elevated or reduced binding protein concentrations without the need for additional tests of
    binding capacity. FT3 determinations should be used as part of a thyroid test strategy,
    which may include free T4 and high sensitivity TSH assays.

    SPECIMEN REQUIREMENTS:
    2ml serum collected in a red top tube with no additive or in a serum separator tube (gel
    barrier). Store in the refrigerator at 2-8 for up to 7 days. For long term storage, freeze at
    -20 C or below. Avoid thaw freeze cycles.

    METHOD: Enhanced Chemiluminescence

    REFERENCES:
    1. Robbins J , Rall J E. Interactions of thyroid hormones and proteins in biological fluids.
    Recent Prog Horm Res 13: 161-202; 1957.
    2. Lewis M. Measurement of free thyroid hormones in health and disease. In Ekins R et
    al (eds), International Symposium on Free Thyroid Hormones. Venice. Excerpta
    Medica:167-180; 1979.
    3. Pinchera A et al. Free thyroid hormones in thyroid disease and effect of thyroid
    replacement therapy: observations by frequent sampling. In Ekins R et al (eds),
    International Symposium on Free Thyroid Hormones. Venice. Excerpta Medica:208-220;
    1979.
    4. Avalos E et al. Diagnostic value of free triiodothyronine in serum. J Nucl Med
    27:1702-1705;1986.

    Normal Range: 2.77-5.27 pg/ml


    Turnaround Time: 1 day

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