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    Pato

    Uploaded by

    John Bisnar
    The document outlines the physiological effects of reduced circulating blood volume, including vasoconstriction of multiple organs, adrenal hormone production and release, impaired detoxification and metabolic deficiencies, intestinal and myocardial injury, changes in cardiac output, oxygen and carbon dioxide exchange, oxygen carrying capacity, sodium and water retention, proliferation of bacteria and endotoxins in the blood, changes in blood pressure, pulse, respiration and mental state, and cellular hypoxia, acidosis, and damage leading to coagulation abnormalities and potential bleeding.

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    Pato

    Uploaded by

    John Bisnar
    25 views3 pages
    The document outlines the physiological effects of reduced circulating blood volume, including vasoconstriction of multiple organs, adrenal hormone production and release, impaired detoxification and metabolic deficiencies, intestinal and myocardial injury, changes in cardiac output, oxygen and carbon dioxide exchange, oxygen carrying capacity, sodium and water retention, proliferation of bacteria and endotoxins in the blood, changes in blood pressure, pulse, respiration and mental state, and cellular hypoxia, acidosis, and damage leading to coagulation abnormalities and potential bleeding.

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    The document outlines the physiological effects of reduced circulating blood volume, including vasoconstriction of multiple organs, adrenal hormone production and release, impaired detoxification and metabolic deficiencies, intestinal and myocardial injury, changes in cardiac output, oxygen and carbon dioxide exchange, oxygen carrying capacity, sodium and water retention, proliferation of bacteria and endotoxins in the blood, changes in blood pressure, pulse, respiration and mental state, and cellular hypoxia, acidosis, and damage leading to coagulation abnormalities and potential bleeding.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    25 views3 pages

    Pato

    Uploaded by

    John Bisnar
    The document outlines the physiological effects of reduced circulating blood volume, including vasoconstriction of multiple organs, adrenal hormone production and release, impaired detoxification and metabolic deficiencies, intestinal and myocardial injury, changes in cardiac output, oxygen and carbon dioxide exchange, oxygen carrying capacity, sodium and water retention, proliferation of bacteria and endotoxins in the blood, changes in blood pressure, pulse, respiration and mental state, and cellular hypoxia, acidosis, and damage leading to coagulation abnormalities and potential bleeding.

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    Download as DOCX, PDF, TXT or read online from Scribd
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    Reduced circulating blood volume Sympathetic response Tissue perfusion to multiple organs

    Kidneys

    Adrenals

    Liver

    GI

    Vasoconstriction

    Lungs

    Acute tubular necrosis

    Production & release of mineralocorticoids & glucocorticoids

    Metabolic deficiencies

    Impaired ability to detoxify

    Intestinal injury

    Myocardial depressant factor release from pancreas

    Cardiac output

    O2/CO2 exchange

    O2 carrying capacity

    Aldosterone

    Na & H2O retention

    Proliferation of bacteria / virus and endotoxins in the blood

    BP

    Weak, thready, rapid pulse

    Sympathetic stimulation

    Oliguria or anuria

    Intravascular volume

    Capillary permeability Pulse pressure Blood to the brain Anxiousness, nervousness, irritability HR

    Adrenal hemorrhage RR Dizziness, fainting, &/or unconsciousness Apathy, confusion, restlessness O2 to tissues

    Respiratory alkalosis

    Cellular hypoxia

    Cell death

    Anaerobic metabolism

    Release of cellular enzymes

    Lactic acid accumulation

    Capillary permeability

    Metabolic acidosis

    Hypercoagulable blood + precipitating factor

    Tissue damage

    Endothelial damage

    Increased tissue thomboplastin

    Intrinsic pathway of coagulation

    Extrinsic pathway of coagulation Fresh frozen plasma Intravascular coagulation (production of microthrombi) Platelets

    Production of thrombi

    Consumption of clotting factors

    Activation of fibrinolytic system Cryoprecipitate Factor VIII Digestion of fibrin clots Blood Transfusion

    Decreased clotting factors

    Thrombocytopenia

    Inhibition of platelet function

    Extensive Bleeding

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