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Material Safety Data Sheet

Acetophenone MSDS
Section 1: Chemical Product and Company Identification
Product Name: Acetophenone Catalog Codes: SLA2425 CAS#: 98-86-2 RTECS: AM5250000 TSCA: TSCA 8(b) inventory: Acetophenone CI#: Not applicable. Synonym: Ketone methyl phenyl Chemical Name: 1-Phenyl-ethanone Chemical Formula: C6H5COCH4 Contact Information: Sciencelab.com, Inc. 14025 Smith Rd. Houston, Texas 77396 US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 Order Online: ScienceLab.com

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Fire Re a c t iv it y P e rs o n a l P ro t e c t io n

CHEMTREC (24HR Emergency Telephone), call: 1-800-424-9300 International CHEMTREC, call: 1-703-527-3887 For non-emergency assistance, call: 1-281-441-4400

Section 2: Composition and Information on Ingredients

Composition: Name Acetophenone CAS # 98-86-2 % by Weight 100

Toxicological Data on Ingredients: Acetophenone: ORAL (LD50): Acute: 815 mg/kg [Rat.]. 740 mg/kg [Mouse]. DERMAL (LD50): Acute: 15900 mg/kg [Rabbit].

Section 3: Hazards Identification

Potential Acute Health Effects: Very hazardous in case of eye contact (irritant). Hazardous in case of skin contact (irritant). Slightly hazardous in case of ingestion, of inhalation. Inflammation of the eye is characterized by redness, watering, and itching. Potential Chronic Health Effects: Very hazardous in case of eye contact (irritant). Hazardous in case of skin contact (irritant). Slightly hazardous in case of ingestion, of inhalation. CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available.

Section 4: First Aid Measures

Eye Contact: p. 1

Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention immediately. Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical attention. Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Serious Inhalation: Not available. Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: Combustible. Auto-Ignition Temperature: 570C (1058F) Flash Points: CLOSED CUP: 77C (170.6F). OPEN CUP: 82.2C (180F) (Cleveland). Flammable Limits: Not available. Products of Combustion: These products are carbon oxides (CO, CO2). Fire Hazards in Presence of Various Substances: Flammable in presence of open flames and sparks, of heat, of oxidizing materials. Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in presence of static discharge: Not available. Fire Fighting Media and Instructions: SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Special Remarks on Fire Hazards: Store away from direct sunlight. When heated to decomposition it emits acrid smoke and fumes. Special Remarks on Explosion Hazards: Not available.

Section 6: Accidental Release Measures

Small Spill: Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large Spill: Combustible material. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. If the product is in its solid form: Use a shovel to put the material into a convenient waste disposal container. If the product is in its liquid form: p. 2

Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.

Section 7: Handling and Storage

Precautions: Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as oxidizing agents, reducing agents, alkalis. Storage: Keep container in a cool, well-ventilated area. Keep container tightly closed and sealed until ready for use. Avoid all possible sources of ignition (spark or flame).

Section 8: Exposure Controls/Personal Protection

Engineering Controls: Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location. Personal Protection: Splash goggles. Lab coat. Gloves. Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure Limits: Not available.

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid. (Liquid.) Odor: Not available. Taste: Not available. Molecular Weight: 120.16 g/mole Color: Colorless to light yellow. pH (1% soln/water): 7 [Neutral.] Boiling Point: 201.7C (395.1F) Melting Point: 19.7C (67.5F) Critical Temperature: Not available. Specific Gravity: 1.03 (Water = 1) Vapor Pressure: 0.1 kPa (@ 20C) Vapor Density: 4.1 (Air = 1) Volatility: Not available. Odor Threshold: Not available. Water/Oil Dist. Coeff.: Not available. Ionicity (in Water): Not available. Dispersion Properties: See solubility in water, methanol, diethyl ether. p. 3

Solubility: Soluble in methanol, diethyl ether. Partially soluble in cold water, hot water.

Section 10: Stability and Reactivity Data

Stability: The product is stable. Instability Temperature: Not available. Conditions of Instability: Not available. Incompatibility with various substances: Reactive with oxidizing agents, reducing agents, alkalis. Corrosivity: Non-corrosive in presence of glass. Special Remarks on Reactivity: Not available. Special Remarks on Corrosivity: Not available. Polymerization: Will not occur.

Section 11: Toxicological Information

Routes of Entry: Eye contact. Toxicity to Animals: Acute oral toxicity (LD50): 740 mg/kg [Mouse]. Acute dermal toxicity (LD50): 15900 mg/kg [Rabbit]. Chronic Effects on Humans: Not available. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant). Slightly hazardous in case of ingestion, of inhalation. Special Remarks on Toxicity to Animals: Not available. Special Remarks on Chronic Effects on Humans: 0900 Detected in maternal milk in human. Special Remarks on other Toxic Effects on Humans: Material is irritating to mucous membranes and upper respiratory tract. Narcotic in high concentrations. Hypnotic.

Section 12: Ecological Information

Ecotoxicity: Not available. BOD5 and COD: Not available. Products of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. Toxicity of the Products of Biodegradation: The products of degradation are more toxic. Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal:

Section 14: Transport Information

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DOT Classification: CLASS 3: Combustible liquid Identification: : FLAMMABLE LIQUIDS, N.O.S. UNNA: UN1993 PG: Not available. Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information

Federal and State Regulations: Pennsylvania RTK: Acetophenone Massachusetts RTK: Acetophenone TSCA 8(b) inventory: Acetophenone SARA 313 toxic chemical notification and release reporting: Acetophenone CERCLA: Hazardous substances.: Acetophenone Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). Other Classifications: WHMIS (Canada): CLASS B-3: Combustible liquid with a flash point between 37.8C (100F) and 93.3C (200F). CLASS D-2B: Material causing other toxic effects (TOXIC). DSCL (EEC): R22- Harmful if swallowed. R38- Irritating to skin. R41- Risk of serious damage to eyes. HMIS (U.S.A.): Health Hazard: 1 Fire Hazard: 2 Reactivity: 0 Personal Protection: j National Fire Protection Association (U.S.A.): Health: 1 Flammability: 2 Reactivity: 0 Specific hazard: Protective Equipment: Gloves. Lab coat. Wear appropriate respirator when ventilation is inadequate. Splash goggles.

Section 16: Other Information

References: -Hawley, G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987. -SAX, N.I. Dangerous Properties of Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984. -The Sigma-Aldrich Library of Chemical Safety Data, Edition II. Other Special Considerations: Not available. Created: 10/09/2005 03:36 PM Last Updated: 11/01/2010 12:00 PM The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or for p. 5

lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.com has been advised of the possibility of such damages.

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