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Material Safety Data Sheet

Phenolphthalein Solution, 1% MSDS
Section 1: Chemical Product and Company Identification
Product Name: Phenolphthalein Solution, 1% Catalog Codes: SLP4165 CAS#: Mixture. RTECS: Not applicable. TSCA: TSCA 8(b) inventory: Water; Isopropyl alcohol; Phenolphthalein, powder CI#: Not applicable. Synonym: Phenolphthalein Solution, 1% in 95% Isopropyl alcohol Chemical Name: Not applicable. Chemical Formula: Not applicable. Contact Information: Sciencelab.com, Inc. 14025 Smith Rd. Houston, Texas 77396 US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 Order Online: ScienceLab.com

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Fire Re a c t iv it y P e rs o n a l P ro t e c t io n

CHEMTREC (24HR Emergency Telephone), call: 1-800-424-9300 International CHEMTREC, call: 1-703-527-3887 For non-emergency assistance, call: 1-281-441-4400

Section 2: Composition and Information on Ingredients

Composition: Name Water Isopropyl alcohol Phenolphthalein, powder CAS # 7732-18-5 67-63-0 77-09-8 % by Weight 4 95 1

Toxicological Data on Ingredients: Isopropyl alcohol: ORAL (LD50): Acute: 5045 mg/kg [Rat]. 3600 mg/kg [Mouse]. 6410 mg/kg [Rabbit]. DERMAL (LD50): Acute: 12800 mg/kg [Rabbit]. Phenolphthalein, powder LD50: Not available. LC50: Not available.

Section 3: Hazards Identification

Potential Acute Health Effects: Hazardous in case of eye contact (irritant), of ingestion, . Slightly hazardous in case of skin contact (irritant, sensitizer, permeator). Non-corrosive for skin. Non-corrosive to the eyes. Non-corrosive for lungs. Potential Chronic Health Effects: CARCINOGENIC EFFECTS: Classified A4 (Not classifiable for human or animal.) by ACGIH, 3 (Not classifiable for human.) by IARC [Isopropyl alcohol]. Classified 1 (Clear evidence.) by NTP [Phenolphthalein, powder]. Classified 2B (Possible for human.) by IARC [Phenolphthalein, powder]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. p. 1

[Phenolphthalein, powder]. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Development toxin [POSSIBLE] [Isopropyl alcohol]. The substance may be toxic to kidneys, liver, skin, central nervous system (CNS). Repeated or prolonged exposure to the substance can produce target organs damage.

Section 4: First Aid Measures

Eye Contact: Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention. Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used. Serious Skin Contact: Not available. Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention if symptoms appear. Serious Inhalation: Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Seek medical attention. Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: Flammable. Auto-Ignition Temperature: The lowest known value is 399C (750.2F) (Isopropyl alcohol). Flash Points: The lowest known value is CLOSED CUP: 11.7C (53.1F). (TAG). OPEN CUP: 23C (73.4F). (Cleveland). (Isopropyl alcohol) Flammable Limits: The greatest known range is LOWER: 2% UPPER: 12.7% (Isopropyl alcohol) Products of Combustion: These products are carbon oxides (CO, CO2). Fire Hazards in Presence of Various Substances: Highly flammable in presence of open flames and sparks, of heat. Flammable in presence of oxidizing materials. Nonflammable in presence of shocks, of reducing materials, of combustible materials, of organic materials, of metals, of acids, of alkalis, of moisture. Explosion Hazards in Presence of Various Substances: Slightly explosive in presence of oxidizing materials. Non-explosive in presence of open flames and sparks, of shocks. Fire Fighting Media and Instructions: Flammable liquid, soluble or dispersed in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use alcohol foam, water spray or fog. Special Remarks on Fire Hazards: Vapor may travel considerable distance to source of ignition and flash back. CAUTION: MAY BURN WITH NEAR INVISIBLE FLAME (Isopropyl alcohol) Special Remarks on Explosion Hazards: Secondary alcohols are readily autooxidized in contact with oxygen or air, forming ketones and hydrogen peroxide. It can become potentially explosive. Explosive in the form of vapor when exposed to heat or flame. May form explosive mixtures with p. 2

air. Isopropyl alcohol + phosgene forms isopropyl chloroformate and hydrogen chloride. In the presence of iron salts, thermal decompositon can occur, whicn in some cases can become explosive. A homogeneous mixture of oncentrated peroxides + isopropyl alcohol are capable of detonation by shock or heat. Barium perchlorate + isopropyl alcohol gives the highly explosive alkyl perchlorates. (Isopropyl alcohol)

Section 6: Accidental Release Measures

Small Spill: Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container. Large Spill: Flammable liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers, basements or confined areas; dike if needed. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.

Section 7: Handling and Storage

Precautions: Keep locked up.. Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Avoid contact with eyes. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents, acids. Storage: Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed and sealed until ready for use. Avoid all possible sources of ignition (spark or flame).

Section 8: Exposure Controls/Personal Protection

Engineering Controls: Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location. Personal Protection: Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves (impervious). Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure Limits: Isopropyl alcohol TWA: 983 STEL: 1230 (mg/m3) [Australia] TWA: 200 STEL: 400 (ppm) from ACGIH (TLV) [United States] [1999] TWA: 980 STEL: 1225 (mg/m3) from NIOSH TWA: 400 STEL: 500 (ppm) from NIOSH TWA: 400 STEL: 500 (ppm) [United Kingdom (UK)] TWA: 999 STEL: 1259 (mg/m3) [United Kingdom (UK)] TWA: 400 STEL: 500 (ppm) from OSHA (PEL) [United States] TWA: 980 STEL: 1225 (mg/m3) from OSHA (PEL) [United States]Consult local authorities for acceptable exposure limits.

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid. Odor: Alcohol like. Taste: Not available. p. 3

Molecular Weight: Not applicable. Color: Clear Colorless. pH (1% soln/water): 8 [Basic.] Boiling Point: The lowest known value is 82.5C (180.5F) (Isopropyl alcohol). Weighted average: 83.21C (181.8F) Melting Point: May start to solidify at -88.5C (-127.3F) based on data for: Isopropyl alcohol. Critical Temperature: The lowest known value is 235C (455F) (Isopropyl alcohol). Specific Gravity: Weighted average: 0.8 (Water = 1) Vapor Pressure: The highest known value is 4.4 kPa (@ 20C) (Isopropyl alcohol). Weighted average: 4.32 kPa (@ 20C) Vapor Density: The highest known value is 2.07 (Air = 1) (Isopropyl alcohol). Weighted average: 2.01 (Air = 1) Volatility: Not available. Odor Threshold: The highest known value is 22 ppm (Isopropyl alcohol) Water/Oil Dist. Coeff.: The product is equally soluble in oil and water. Ionicity (in Water): Not available. Dispersion Properties: See solubility in water, diethyl ether, acetone. Solubility: Easily soluble in cold water, hot water, diethyl ether, acetone.

Section 10: Stability and Reactivity Data

Stability: The product is stable. Instability Temperature: Not available. Conditions of Instability: Heat, ignition sources (sparks, flames), incompatible materials Incompatibility with various substances: Reactive with oxidizing agents, acids. Corrosivity: Non-corrosive in presence of glass. Special Remarks on Reactivity: Reactcs violently with hydrogen-palladium combination. Incompatible with acetaldehyde, chlorine, ethylene oxide, isocyanates. (Isopropyl alcohol) Special Remarks on Corrosivity: Not available. Polymerization: Will not occur.

Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Eye contact. Inhalation. Ingestion. Toxicity to Animals: Acute oral toxicity (LD50): 3600 mg/kg [Mouse]. (Isopropyl alcohol). Acute dermal toxicity (LD50): 12800 mg/kg [Rabbit]. (Isopropyl alcohol). Chronic Effects on Humans: CARCINOGENIC EFFECTS: Classified A4 (Not classifiable for human or animal.) by ACGIH, 3 (Not classifiable for human.) by IARC [Isopropyl alcohol]. Classified 1 (Clear evidence.) by NTP [Phenolphthalein, powder]. Classified 2B (Possible for human.) by IARC [Phenolphthalein, powder]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. [Phenolphthalein, powder]. DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female, Development toxin [POSSIBLE] [Isopropyl alcohol]. Contains material which may cause damage to the following organs: kidneys, liver, skin, central nervous system (CNS). p. 4

Other Toxic Effects on Humans: Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant, sensitizer, permeator). Special Remarks on Toxicity to Animals: Not available. Special Remarks on Chronic Effects on Humans: Maycauseadversereproductive/teratogeniceffects(fertility,fetoxicity,developm e n t a l abnormalities(developmental toxin)) based on animal studies. Detected in maternal milk in human. (Isopropyl alcohol) Contains Phenolphthalein which may affect genetic material and cause cancer based on animal data Special Remarks on other Toxic Effects on Humans:

Section 12: Ecological Information

Ecotoxicity: Not available. BOD5 and COD: Not available. Products of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic. Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.

Section 14: Transport Information

DOT Classification: CLASS 3: Flammable liquid. Identification: : Isopropanol, Solution (Isopropyl alcohol) UNNA: 1219 PG: II Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information

Federal and State Regulations: California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer, birth defects or other reproductive harm, which would require a warning under the statute: Phenolphthalein, powder California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: Phenolphthalein, powder Rhode Island RTK hazardous substances: Isopropyl alcohol Pennsylvania RTK: Isopropyl alcohol Florida: Isopropyl alcohol Minnesota: Isopropyl alcohol Massachusetts RTK: Isopropyl alcohol New Jersey: Isopropyl alcohol TSCA 8(b) inventory: Water; Isopropyl alcohol; Phenolphthalein, powder Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). Other Classifications: WHMIS (Canada): Not controlled under WHMIS (Canada). DSCL (EEC): R11- Highly flammable. R36- Irritating to eyes. R45- May cause cancer. S2- Keep out of the reach of children. S46- If swallowed, seek medical advice immediately and show this container or label. S53- Avoid exposure - obtain special instructions before use. p. 5

HMIS (U.S.A.): Health Hazard: 2 Fire Hazard: 3 Reactivity: 0 Personal Protection: j National Fire Protection Association (U.S.A.): Health: 1 Flammability: 3 Reactivity: 0 Specific hazard: Protective Equipment: Gloves (impervious). Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Splash goggles.

Section 16: Other Information

References: Not available. Other Special Considerations: Not available. Created: 10/10/2005 11:18 AM Last Updated: 05/21/2013 12:00 PM The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.com has been advised of the possibility of such damages.

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