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Material Safety Data Sheet

1,2,4-Trichlorobenzene MSDS

Section 1: Chemical Product and Company Identification

Product Name: 1,2,4-Trichlorobenzene Contact Information:

Catalog Codes: SLT3619 Sciencelab.com, Inc.
14025 Smith Rd.
CAS#: 120-82-1 Houston, Texas 77396
RTECS: DC2100000 US Sales: 1-800-901-7247
International Sales: 1-281-441-4400
TSCA: TSCA 8(b) inventory: 1,2,4-Trichlorobenzene
Order Online: ScienceLab.com
CI#: Not applicable.
CHEMTREC (24HR Emergency Telephone), call:
Synonym: 1-800-424-9300
Chemical Name: 1,2,4,-Trichlorobenzene International CHEMTREC, call: 1-703-527-3887
Chemical Formula: C6H3Cl3 For non-emergency assistance, call: 1-281-441-4400

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

{1,2,4-}Trichlorobenzene 120-82-1 100

Toxicological Data on Ingredients: 1,2,4-Trichlorobenzene: ORAL (LD50): Acute: 756 mg/kg [Rat.]. 300 mg/kg [Mouse].
DERMAL (LD50): Acute: 6139 mg/kg [Rat.].

Section 3: Hazards Identification

Potential Acute Health Effects:

Extremely hazardous in case of skin contact (irritant, permeator), of eye contact (irritant). Very hazardous in case of ingestion,
of inhalation. Slightly hazardous in case of skin contact (sensitizer). Inflammation of the eye is characterized by redness,
watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to blood, kidneys, liver, upper respiratory tract. Repeated
or prolonged exposure to the substance can produce target organs damage.

Section 4: First Aid Measures

Eye Contact: Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention.

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Skin Contact:
After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running
water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an
emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing.
Serious Skin Contact:
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical
attention.
Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
Serious Inhalation:
Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If
breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medical
attention.
Ingestion:
Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that
the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen tight clothing such as a collar,
tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.
Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: 571C (1059.8F)
Flash Points: CLOSED CUP: 110C (230F).
Flammable Limits: LOWER: 2.5% UPPER: 6.6%
Products of Combustion: These products are carbon oxides (CO, CO2), halogenated compounds.
Fire Hazards in Presence of Various Substances:
Flammable in presence of open flames and sparks, of oxidizing materials. Slightly flammable to flammable in presence of
heat, of reducing materials, of combustible materials. Non-flammable in presence of moisture.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in
presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Keep container tightly closed.
Special Remarks on Explosion Hazards: Not available.

Section 6: Accidental Release Measures

Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal.
Large Spill:
If the product is in its solid form: Use a shovel to put the material into a convenient waste disposal container. If the product is
in its liquid form: Absorb with an inert material and put the spilled material in an appropriate waste disposal. Be careful that the
product is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.

Section 7: Handling and Storage

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Precautions:
Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under
a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapour/spray. In case
of insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical advice immediately and show the
container or the label. Avoid contact with skin and eyes Keep away from incompatibles such as oxidizing agents, reducing
agents, organic materials, metals, acids, alkalis.
Storage:
Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in a
cool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizing
agents.

Section 8: Exposure Controls/Personal Protection

Engineering Controls:
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective
threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.
Personal Protection:
Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
product.
Exposure Limits:
TWA: 5 (ppm) TWA: 37 (mg/m3) Consult local authorities for acceptable exposure limits.

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid. (Liquid.)

Odor: Pungent. (Slight.)
Taste: Toxic by ingestion.
Molecular Weight: 181.46 g/mole
Color: Colorless.
pH (1% soln/water): Not applicable.
Boiling Point: 213C (415.4F)
Melting Point: 17C (62.6F)
Critical Temperature: Not available.
Specific Gravity: 1.45 (Water = 1)
Vapor Pressure: Not available.
Vapor Density: 6.26 (Air = 1)
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water, methanol, diethyl ether, n-octanol.

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Solubility:
Easily soluble in diethyl ether. Soluble in methanol, n-octanol. Insoluble in cold water, hot water.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.
Conditions of Instability: Not available.
Incompatibility with various substances:
Highly reactive with oxidizing agents. Reactive with reducing agents, organic materials, metals, acids, alkalis.
Corrosivity:
Slightly corrosive to corrosive in presence of steel, of copper. Non-corrosive in presence of glass.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: No.

Section 11: Toxicological Information

Routes of Entry: Dermal contact. Eye contact. Inhalation. Ingestion.

Toxicity to Animals:
Acute oral toxicity (LD50): 300 mg/kg [Mouse]. Acute dermal toxicity (LD50): 6139 mg/kg [Rat.].
Chronic Effects on Humans: The substance is toxic to blood, kidneys, liver, upper respiratory tract.
Other Toxic Effects on Humans:
Extremely hazardous in case of skin contact (irritant, permeator). Very hazardous in case of ingestion, of inhalation. Slightly
hazardous in case of skin contact (sensitizer).
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Can cause gastrointestinal disturbances.
Special Remarks on other Toxic Effects on Humans: Exposure can cause nausea, headache and vomiting.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are more toxic.
Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal:

Section 14: Transport Information

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DOT Classification: CLASS 6.1: Poisonous material.
Identification: : Trichlorobenzene : UN2321 PG: III
Special Provisions for Transport: Marine Pollutant

Section 15: Other Regulatory Information

Federal and State Regulations:

Pennsylvania RTK: 1,2,4-Trichlorobenzene Florida: 1,2,4-Trichlorobenzene Minnesota: 1,2,4-Trichlorobenzene Massachusetts
RTK: 1,2,4-Trichlorobenzene New Jersey: 1,2,4-Trichlorobenzene TSCA 8(b) inventory: 1,2,4-Trichlorobenzene SARA
313 toxic chemical notification and release reporting: 1,2,4-Trichlorobenzene CERCLA: Hazardous substances.: 1,2,4-
Trichlorobenzene
Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
Other Classifications:
WHMIS (Canada):
CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC). CLASS D-2B: Material causing other toxic effects
(TOXIC).
DSCL (EEC):
R38- Irritating to skin. R41- Risk of serious damage to eyes.
HMIS (U.S.A.):
Health Hazard: 2
Fire Hazard: 1
Reactivity: 0
Personal Protection: h
National Fire Protection Association (U.S.A.):
Health: 2
Flammability: 1
Reactivity: 0
Specific hazard:
Protective Equipment:
Gloves. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator
when ventilation is inadequate. Splash goggles.

Section 16: Other Information

References:
-Material safety data sheet emitted by: la Commission de la Sant et de la Scurit du Travail du Qubec. -Hawley,
G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987. -The Sigma-Aldrich Library
of Chemical Safety Data, Edition II.
Other Special Considerations: Not available.
Created: 10/10/2005 08:31 PM
Last Updated: 05/21/2013 12:00 PM

The information above is believed to be accurate and represents the best information currently available to us. However, we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume

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no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for
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