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Material Safety Data Sheet

p-Xylene MSDS

Section 1: Chemical Product and Company Identification

Product Name: p-Xylene Contact Information:

Catalog Codes: SLX1120 Sciencelab.com, Inc.
14025 Smith Rd.
CAS#: 106-42-3 Houston, Texas 77396
RTECS: ZE2625000 US Sales: 1-800-901-7247
International Sales: 1-281-441-4400
TSCA: TSCA 8(b) inventory: p-Xylene
Order Online: ScienceLab.com
CI#: Not applicable.
CHEMTREC (24HR Emergency Telephone), call:
Synonym: p-Methyltoluene 1-800-424-9300
Chemical Name: 1,4-Dimethylbenzene International CHEMTREC, call: 1-703-527-3887
Chemical Formula: C6H4(CH3)2 For non-emergency assistance, call: 1-281-441-4400

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

{p-}Xylene 106-42-3 100

Toxicological Data on Ingredients: p-Xylene: ORAL (LD50): Acute: 5000 mg/kg [Rat.]. DERMAL (LD50): Acute: 12400 mg/
kg [Rabbit.]. VAPOR (LC50): Acute: 4550 ppm 4 hour(s) [Rat].

Section 3: Hazards Identification

Potential Acute Health Effects:

Very hazardous in case of skin contact (irritant), of eye contact (irritant). Slightly hazardous in case of skin contact (permeator),
of ingestion, of inhalation. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is
characterized by itching, scaling, reddening, or, occasionally, blistering.
Potential Chronic Health Effects:
Hazardous in case of skin contact (irritant), of eye contact (irritant). Slightly hazardous in case of skin contact (permeator), of
ingestion, of inhalation. CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC
EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to blood, kidneys, the nervous
system, liver. Repeated or prolonged exposure to the substance can produce target organs damage.

Section 4: First Aid Measures

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Eye Contact: Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention.
Skin Contact:
After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running
water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an
emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing.
Serious Skin Contact:
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical
attention.
Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
Serious Inhalation: Not available.
Ingestion:
Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that
the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen tight clothing such as a collar,
tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.
Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: Flammable.

Auto-Ignition Temperature: 527°C (980.6°F)
Flash Points: CLOSED CUP: 25°C (77°F). OPEN CUP: 28.9°C (84°F) (Cleveland).
Flammable Limits: LOWER: 1.1% UPPER: 7%
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances: Highly flammable in presence of open flames and sparks, of heat.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in
presence of static discharge: Not available.
Fire Fighting Media and Instructions:
Flammable liquid, insoluble in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray or fog. Cool
containing vessels with water jet in order to prevent pressure build-up, autoignition or explosion.
Special Remarks on Fire Hazards:
Explosive in the form of vapor when exposed to heat or flame. Vapor may travel considerable distance to source of ignition
and flash back. When heated to decomposition it emits acrid smoke and irritating fumes.
Special Remarks on Explosion Hazards: Not available.

Section 6: Accidental Release Measures

Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal.
Large Spill:
Toxic flammable liquid, insoluble or very slightly soluble in water. Keep away from heat. Keep away from sources of ignition.
Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material. Do not get water inside container.
Do not touch spilled material. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition
sources. Call for assistance on disposal. Be careful that the product is not present at a concentration level above TLV. Check
TLV on the MSDS and with local authorities.

Section 7: Handling and Storage

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Precautions:
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not
breathe gas/fumes/ vapour/spray. If ingested, seek medical advice immediately and show the container or the label. Avoid
contact with skin and eyes Keep away from incompatibles such as oxidizing agents.
Storage:
Flammable materials should be stored in a separate safety storage cabinet or room. Keep away from heat. Keep away from
sources of ignition. Keep container tightly closed. Keep in a cool, well-ventilated place. Ground all equipment containing
material. A refrigerated room would be preferable for materials with a flash point lower than 37.8°C (100°F).

Section 8: Exposure Controls/Personal Protection

Engineering Controls:
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective
threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.
Personal Protection:
Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
product.
Exposure Limits:
TWA: 100 STEL: 150 (ppm) from ACGIH (TLV) TWA: 434 STEL: 651 (mg/m3) from ACGIHConsult local authorities for
acceptable exposure limits.

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid. (Liquid.)

Odor: Not available.
Taste: Not available.
Molecular Weight: 106.17 g/mole
Color: Colorless.
pH (1% soln/water): Not applicable.
Boiling Point: 138°C (280.4°F)
Melting Point: 12°C (53.6°F)
Critical Temperature: Not available.
Specific Gravity: 0.86 (Water = 1)
Vapor Pressure: 9 mm of Hg (@ 20°C)
Vapor Density: 3.7 (Air = 1)
Volatility: Not available.
Odor Threshold: 0.62 ppm
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water, methanol, diethyl ether.

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Solubility:
Easily soluble in methanol, diethyl ether. Insoluble in cold water, hot water.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.
Conditions of Instability: Not available.
Incompatibility with various substances: Reactive with oxidizing agents.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: No.

Section 11: Toxicological Information

Routes of Entry: Eye contact.

Toxicity to Animals:
WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE. Acute oral
toxicity (LD50): 5000 mg/kg [Rat.]. Acute dermal toxicity (LD50): 12400 mg/kg [Rabbit.]. Acute toxicity of the vapor (LC50):
4550 ppm 4 hour(s) [Rat].
Chronic Effects on Humans: The substance is toxic to blood, kidneys, the nervous system, liver.
Other Toxic Effects on Humans:
Very hazardous in case of skin contact (irritant). Slightly hazardous in case of skin contact (permeator), of ingestion, of
inhalation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans:
0347 Animal: embryotoxic, foetotoxic, passes through the placental barrier. 0900 Detected in maternal milk in human. Narcotic
effect; may cause nervous system disturbances.
Special Remarks on other Toxic Effects on Humans: Material is irritating to mucous membranes and upper respiratory
tract.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are more toxic.
Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

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Waste Disposal:

Section 14: Transport Information

DOT Classification: Class 3: Flammable liquid.

Identification: : Xylene : UN1307 PG: III
Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information

Federal and State Regulations:

Pennsylvania RTK: p-Xylene Florida: p-Xylene Massachusetts RTK: p-Xylene New Jersey: p-Xylene TSCA 8(b) inventory: p-
Xylene SARA 313 toxic chemical notification and release reporting: p-Xylene CERCLA: Hazardous substances.: p-Xylene
Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
Other Classifications:
WHMIS (Canada):
CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F). CLASS D-2B: Material causing other toxic effects
(TOXIC).
DSCL (EEC):
R10- Flammable. R38- Irritating to skin. R41- Risk of serious damage to eyes. R48/20- Harmful: danger of serious damage to
health by prolonged exposure through inhalation.
HMIS (U.S.A.):
Health Hazard: 2
Fire Hazard: 3
Reactivity: 0
Personal Protection: h
National Fire Protection Association (U.S.A.):
Health: 2
Flammability: 3
Reactivity: 0
Specific hazard:
Protective Equipment:
Gloves. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator
when ventilation is inadequate. Splash goggles.

Section 16: Other Information

References:
-Hawley, G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987. -Material safety
data sheet emitted by: la Commission de la Santé et de la Sécurité du Travail du Québec. -SAX, N.I. Dangerous
Properties of Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984. -The Sigma-Aldrich Library of Chemical Safety
Data, Edition II. -Guide de la loi et du règlement sur le transport des marchandises dangeureuses au canada. Centre de
conformité internatinal Ltée. 1986.

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Other Special Considerations: Not available.
Created: 10/10/2005 08:33 PM
Last Updated: 05/21/2013 12:00 PM

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